Lipids and cancer: Emerging roles in pathogenesis, diagnosis and therapeutic intervention LM Butler, Y Perone, J Dehairs, LE Lupien, V de Laat, A Talebi, M Loda, ... Advanced drug delivery reviews 159, 245-293, 2020 | 489 | 2020 |
Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity K Vriens, S Christen, S Parik, D Broekaert, K Yoshinaga, A Talebi, ... Nature 566 (7744), 403-406, 2019 | 427 | 2019 |
CRISP-ID: decoding CRISPR mediated indels by Sanger sequencing J Dehairs, A Talebi, Y Cherifi, JV Swinnen Scientific reports 6 (1), 28973, 2016 | 251 | 2016 |
Loss of chromosome 8p governs tumor progression and drug response by altering lipid metabolism Y Cai, J Crowther, T Pastor, LA Asbagh, MF Baietti, M De Troyer, ... Cancer cell 29 (5), 751-766, 2016 | 199 | 2016 |
Non‐small cell lung cancer is characterized by dramatic changes in phospholipid profiles E Marien, M Meister, T Muley, S Fieuws, S Bordel, R Derua, J Spraggins, ... International Journal of Cancer 137 (7), 1539-1548, 2015 | 192 | 2015 |
Low TREM1 expression in whole blood predicts anti-TNF response in inflammatory bowel disease B Verstockt, S Verstockt, J Dehairs, V Ballet, H Blevi, WJ Wollants, ... EBioMedicine 40, 733-742, 2019 | 164 | 2019 |
Human DECR1 is an androgen-repressed survival factor that regulates PUFA oxidation to protect prostate tumor cells from ferroptosis ZD Nassar, CY Mah, J Dehairs, IJG Burvenich, S Irani, MM Centenera, ... Elife 9, e54166, 2020 | 148 | 2020 |
Sustained SREBP-1-dependent lipogenesis as a key mediator of resistance to BRAF-targeted therapy A Talebi, J Dehairs, F Rambow, A Rogiers, D Nittner, R Derua, ... Nature communications 9 (1), 2500, 2018 | 133 | 2018 |
Stearoyl-CoA desaturase-1 impairs the reparative properties of macrophages and microglia in the brain JFJ Bogie, E Grajchen, E Wouters, AG Corrales, T Dierckx, S Vanherle, ... Journal of Experimental Medicine 217 (5), 2020 | 112 | 2020 |
Saturated fatty acids induce NLRP3 activation in human macrophages through K+ efflux resulting from phospholipid saturation and Na, K-ATPase disruption MA Gianfrancesco, J Dehairs, L L'homme, G Herinckx, N Esser, O Jansen, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2019 | 86 | 2019 |
Identification of drugs that restore primary cilium expression in cancer cells NA Khan, N Willemarck, A Talebi, A Marchand, MM Binda, J Dehairs, ... Oncotarget 7 (9), 9975, 2016 | 82 | 2016 |
ELOVL5 is a critical and targetable fatty acid elongase in prostate cancer MM Centenera, JS Scott, J Machiels, ZD Nassar, DC Miller, I Zinonos, ... Cancer research 81 (7), 1704-1718, 2021 | 77 | 2021 |
Expression levels of 4 genes in colon tissue might be used to predict which patients will enter endoscopic remission after vedolizumab therapy for inflammatory bowel diseases B Verstockt, S Verstockt, M Veny, J Dehairs, K Arnauts, G Van Assche, ... Clinical Gastroenterology and Hepatology 18 (5), 1142-1151. e10, 2020 | 74 | 2020 |
Lipidomic profiling of clinical prostate cancer reveals targetable alterations in membrane lipid composition LM Butler, CY Mah, J Machiels, AD Vincent, S Irani, SM Mutuku, ... Cancer research 81 (19), 4981-4993, 2021 | 68 | 2021 |
Phospholipid profiling identifies acyl chain elongation as a ubiquitous trait and potential target for the treatment of lung squamous cell carcinoma E Marien, M Meister, T Muley, TG Del Pulgar, R Derua, JM Spraggins, ... Oncotarget 7 (11), 12582, 2016 | 68 | 2016 |
Fat induces glucose metabolism in nontransformed liver cells and promotes liver tumorigenesis LA Broadfield, JAG Duarte, R Schmieder, D Broekaert, K Veys, M Planque, ... Cancer research 81 (8), 1988-2001, 2021 | 63 | 2021 |
Regulatory T cell differentiation is controlled by αKG-induced alterations in mitochondrial metabolism and lipid homeostasis MI Matias, CS Yong, A Foroushani, C Goldsmith, C Mongellaz, E Sezgin, ... Cell reports 37 (5), 2021 | 58 | 2021 |
ORP5/8 and MIB/MICOS link ER-mitochondria and intra-mitochondrial contacts for non-vesicular transport of phosphatidylserine VF Monteiro-Cardoso, L Rochin, A Arora, A Houcine, E Jääskeläinen, ... Cell reports 40 (12), 2022 | 52 | 2022 |
Endocytosis of very low-density lipoproteins: an unexpected mechanism for lipid acquisition by breast cancer cells [S] LE Lupien, K Bloch, J Dehairs, NA Traphagen, WW Feng, WL Davis, ... Journal of lipid research 61 (2), 205-218, 2020 | 51 | 2020 |
The transfer of sphingomyelinase contributes to drug resistance in multiple myeloma S Faict, I Oudaert, L D’Auria, J Dehairs, K Maes, P Vlummens, ... Cancers 11 (12), 1823, 2019 | 50 | 2019 |