Regulation of PTEN transcription by p53 V Stambolic, D MacPherson, D Sas, Y Lin, B Snow, Y Jang, S Benchimol, ... Molecular cell 8 (2), 317-325, 2001 | 1241 | 2001 |
Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data CM Rudin, JT Poirier, LA Byers, C Dive, A Dowlati, J George, JV Heymach, ... Nature Reviews Cancer 19 (5), 289-297, 2019 | 1037 | 2019 |
High incidence of breast and endometrial neoplasia resembling human Cowden syndrome in pten+/− mice V Stambolic, MS Tsao, D Macpherson, A Suzuki, WB Chapman, TW Mak Cancer research 60 (13), 3605-3611, 2000 | 492 | 2000 |
Cell death attenuation byUsurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex DM Rasper, JP Vaillancourt, S Hadano, VM Houtzager, I Seiden, ... Cell Death & Differentiation 5 (4), 271-288, 1998 | 443 | 1998 |
Cell type-specific effects of Rb deletion in the murine retina D MacPherson, J Sage, T Kim, D Ho, ME McLaughlin, T Jacks Genes & development 18 (14), 1681-1694, 2004 | 270 | 2004 |
miR-17∼ 92 cooperates with RB pathway mutations to promote retinoblastoma K Conkrite, M Sundby, S Mukai, JM Thomson, D Mu, SM Hammond, ... Genes & development 25 (16), 1734-1745, 2011 | 231 | 2011 |
Small cell lung cancer: can recent advances in biology and molecular biology be translated into improved outcomes? PA Bunn Jr, JD Minna, A Augustyn, AF Gazdar, Y Ouadah, MA Krasnow, ... Journal of Thoracic Oncology 11 (4), 453-474, 2016 | 209 | 2016 |
Targeting NOTCH activation in small cell lung cancer through LSD1 inhibition A Augert, E Eastwood, AH Ibrahim, N Wu, E Grunblatt, R Basom, D Liggitt, ... Science signaling 12 (567), eaau2922, 2019 | 199 | 2019 |
p53 Accumulation, defective cell proliferation, and early embryonic lethality in mice lacking tsg101 J Ruland, C Sirard, A Elia, D MacPherson, A Wakeham, L Li, ... Proceedings of the National Academy of Sciences 98 (4), 1859-1864, 2001 | 186 | 2001 |
Conditional Mutation of Rb Causes Cell Cycle Defects without Apoptosis in the Central Nervous System D MacPherson, J Sage, D Crowley, A Trumpp, RT Bronson, T Jacks Molecular and cellular biology 23 (3), 1044-1053, 2003 | 185 | 2003 |
New approaches to SCLC therapy: from the laboratory to the clinic JT Poirier, J George, TK Owonikoko, A Berns, E Brambilla, LA Byers, ... Journal of thoracic oncology 15 (4), 520-540, 2020 | 169 | 2020 |
Crebbp Loss Drives Small Cell Lung Cancer and Increases Sensitivity to HDAC Inhibition D Jia, A Augert, DW Kim, E Eastwood, N Wu, AH Ibrahim, KB Kim, ... Cancer discovery 8 (11), 1422-1437, 2018 | 164 | 2018 |
Lung cancer subtypes generate unique immune responses SE Busch, ML Hanke, J Kargl, HE Metz, D MacPherson, AMG Houghton The Journal of Immunology 197 (11), 4493-4503, 2016 | 161 | 2016 |
Defective apoptosis and B‐cell lymphomas in mice with p53 point mutation at Ser 23 D MacPherson, J Kim, T Kim, BK Rhee, CTM van Oostrom, RA DiTullio Jr, ... The EMBO journal 23 (18), 3689-3699, 2004 | 153 | 2004 |
PTEN is a potent suppressor of small cell lung cancer M Cui, A Augert, M Rongione, K Conkrite, S Parazzoli, AY Nikitin, ... Molecular Cancer Research 12 (5), 654-659, 2014 | 140 | 2014 |
The comparative pathology of genetically engineered mouse models for neuroendocrine carcinomas of the lung AF Gazdar, TK Savage, JE Johnson, A Berns, J Sage, RI Linnoila, ... Journal of thoracic oncology 10 (4), 553-564, 2015 | 128 | 2015 |
Genetic requirement for Mycl and efficacy of RNA Pol I inhibition in mouse models of small cell lung cancer DW Kim, N Wu, YC Kim, PF Cheng, R Basom, D Kim, CT Dunn, AY Lee, ... Genes & development 30 (11), 1289-1299, 2016 | 111 | 2016 |
Small cell lung cancer exhibits frequent inactivating mutations in the histone methyltransferase KMT2D/MLL2: CALGB 151111 (Alliance) A Augert, Q Zhang, B Bates, M Cui, X Wang, G Wildey, A Dowlati, ... Journal of Thoracic Oncology 12 (4), 704-713, 2017 | 95 | 2017 |
Murine bilateral retinoblastoma exhibiting rapid‐onset, metastatic progression and N‐myc gene amplification D MacPherson, K Conkrite, M Tam, S Mukai, D Mu, T Jacks The EMBO journal 26 (3), 784-794, 2007 | 89 | 2007 |
MYCN drives chemoresistance in small cell lung cancer while USP7 inhibition can restore chemosensitivity E Grunblatt, N Wu, H Zhang, X Liu, JP Norton, Y Ohol, P Leger, JB Hiatt, ... Genes & Development 34 (17-18), 1210-1226, 2020 | 81 | 2020 |