The mechanisms of Hedgehog signalling and its roles in development and disease J Briscoe, PP Thérond Nature reviews Molecular cell biology 14 (7), 416-429, 2013 | 1960 | 2013 |
A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube J Briscoe, A Pierani, TM Jessell, J Ericson Cell 101 (4), 435-445, 2000 | 1474 | 2000 |
Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling J Ericson, P Rashbass, A Schedl, S Brenner-Morton, A Kawakami, ... Cell 90 (1), 169-180, 1997 | 1235 | 1997 |
The protein tyrosine kinase JAK1 complements defects in interferon-α/β and-γ signal transduction M Müller, J Briscoe, C Laxton, D Guschin, A Ziemiecki, O Silvennoinen, ... Nature 366 (6451), 129-135, 1993 | 956 | 1993 |
Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling J Briscoe, L Sussel, P Serup, D Hartigan-O'Connor, TM Jessell, ... Nature 398 (6728), 622-627, 1999 | 921 | 1999 |
Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional network E Dessaud, AP McMahon, J Briscoe Oxford University Press for The Company of Biologists Limited 135 (15), 2489 …, 2008 | 869 | 2008 |
Specification of neuronal fates in the ventral neural tube J Briscoe, J Ericson Current opinion in neurobiology 11 (1), 43-49, 2001 | 685 | 2001 |
Interpretation of the sonic hedgehog morphogen gradient by a temporal adaptation mechanism E Dessaud, LL Yang, K Hill, B Cox, F Ulloa, A Ribeiro, A Mynett, ... Nature 450 (7170), 717-720, 2007 | 650 | 2007 |
A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin‐6. D Guschin, N Rogers, J Briscoe, B Witthuhn, D Watling, F Horn, ... The EMBO journal 14 (7), 1421-1429, 1995 | 624 | 1995 |
The interpretation of morphogen gradients HL Ashe, J Briscoe Oxford University Press for The Company of Biologists Limited 133 (3), 385-394, 2006 | 603 | 2006 |
Neural crest development is regulated by the transcription factor Sox9 M Cheung, J Briscoe Oxford University Press for The Company of Biologists Limited 130 (23), 5681 …, 2003 | 565 | 2003 |
The transcriptional control of trunk neural crest induction, survival, and delamination M Cheung, MC Chaboissier, A Mynett, E Hirst, A Schedl, J Briscoe Developmental cell 8 (2), 179-192, 2005 | 504 | 2005 |
Morphogen rules: design principles of gradient-mediated embryo patterning J Briscoe, S Small Development 142 (23), 3996-4009, 2015 | 497 | 2015 |
Complementation of a mutant cell line: central role of the 91 kDa polypeptide of ISGF3 in the interferon‐alpha and‐gamma signal transduction pathways. M Müller, C Laxton, J Briscoe, C Schindler, T Improta, JE Darnell Jr, ... The EMBO journal 12 (11), 4221-4228, 1993 | 494 | 1993 |
Gene regulatory logic for reading the Sonic Hedgehog signaling gradient in the vertebrate neural tube N Balaskas, A Ribeiro, J Panovska, E Dessaud, N Sasai, KM Page, ... Cell 148 (1), 273-284, 2012 | 478 | 2012 |
A hedgehog-insensitive form of patched provides evidence for direct long-range morphogen activity of sonic hedgehog in the neural tube J Briscoe, Y Chen, TM Jessell, G Struhl Molecular cell 7 (6), 1279-1291, 2001 | 477 | 2001 |
Graded sonic hedgehog signaling and the specification of cell fate in the ventral neural tube J Ericson, J Briscoe, P Rashbass, V Van Heyningen, TM Jessell Cold Spring Harbor symposia on quantitative biology 62, 451-466, 1997 | 439 | 1997 |
SOX9 induces and maintains neural stem cells CE Scott, SL Wynn, A Sesay, C Cruz, M Cheung, MVG Gaviro, S Booth, ... Nature neuroscience 13 (10), 1181-1189, 2010 | 417 | 2010 |
In Vitro Generation of Neuromesodermal Progenitors Reveals Distinct Roles for Wnt Signalling in the Specification of Spinal Cord and Paraxial Mesoderm Identity M Gouti, A Tsakiridis, FJ Wymeersch, Y Huang, J Kleinjung, V Wilson, ... PLoS biology 12 (8), e1001937, 2014 | 404 | 2014 |
Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity M Persson, D Stamataki, P te Welscher, E Andersson, J Böse, U Rüther, ... Genes & development 16 (22), 2865-2878, 2002 | 371 | 2002 |