Evaluating cell lines as tumour models by comparison of genomic profiles S Domcke, R Sinha, DA Levine, C Sander, N Schultz Nature communications 4 (1), 2126, 2013 | 1597 | 2013 |
Impact of cytosine methylation on DNA binding specificities of human transcription factors Y Yin, E Morgunova, A Jolma, E Kaasinen, B Sahu, S Khund-Sayeed, ... Science 356 (6337), eaaj2239, 2017 | 1234 | 2017 |
Competition between DNA methylation and transcription factors determines binding of NRF1 S Domcke, AF Bardet, P Adrian Ginno, D Hartl, L Burger, D Schübeler Nature 528 (7583), 575-579, 2015 | 518 | 2015 |
A human cell atlas of fetal chromatin accessibility S Domcke, AJ Hill, RM Daza, J Cao, DR O’Day, HA Pliner, KA Aldinger, ... Science 370 (6518), eaba7612, 2020 | 358 | 2020 |
Molecular mechanisms for the RNA-dependent ATPase activity of Upf1 and its regulation by Upf2 S Chakrabarti, U Jayachandran, F Bonneau, F Fiorini, C Basquin, ... Molecular cell 41 (6), 693-703, 2011 | 298 | 2011 |
Evidence that direct inhibition of transcription factor binding is the prevailing mode of gene and repeat repression by DNA methylation S Kaluscha, S Domcke, C Wirbelauer, MB Stadler, S Durdu, L Burger, ... Nature genetics 54 (12), 1895-1906, 2022 | 116 | 2022 |
A time-resolved, multi-symbol molecular recorder via sequential genome editing J Choi, W Chen, A Minkina, FM Chardon, CC Suiter, SG Regalado, ... Nature 608 (7921), 98-107, 2022 | 113 | 2022 |
A reference cell tree will serve science better than a reference cell atlas S Domcke, J Shendure Cell 186 (6), 1103-1114, 2023 | 74 | 2023 |
Evaluating cell lines as tumour models by comparison of genomic profiles. Nat Commun 4: 2126 S Domcke, R Sinha, DA Levine, C Sander, N Schultz | 29 | 2013 |
DNA sequence and chromatin modifiers cooperate to confer epigenetic bistability at imprinting control regions S Butz, N Schmolka, ID Karemaker, R Villaseñor, I Schwarz, S Domcke, ... Nature genetics 54 (11), 1702-1710, 2022 | 21 | 2022 |
Multiplex, single-cell CRISPRa screening for cell type specific regulatory elements FM Chardon, TA McDiarmid, NF Page, RM Daza, BK Martin, S Domcke, ... Nature Communications 15 (1), 8209, 2024 | 17 | 2024 |
A temporally resolved, multiplex molecular recorder based on sequential genome editing J Choi, W Chen, A Minkina, FM Chardon, CC Suiter, SG Regalado, ... BioRxiv, 2021.11. 05.467388, 2021 | 14 | 2021 |
Multiplex profiling of developmental enhancers with quantitative, single-cell expression reporters JB Lalanne, SG Regalado, S Domcke, D Calderon, B Martin, T Li, ... bioRxiv, 2022.12. 10.519236, 2022 | 12 | 2022 |
Multiplex profiling of developmental cis-regulatory elements with quantitative single-cell expression reporters JB Lalanne, SG Regalado, S Domcke, D Calderon, BK Martin, X Li, T Li, ... Nature Methods, 1-11, 2024 | 7 | 2024 |
Multiplex single-cell chemical genomics reveals the kinase dependence of the response to targeted therapy JL McFaline-Figueroa, S Srivatsan, AJ Hill, M Gasperini, DL Jackson, ... Cell Genomics 4 (2), 2024 | 7 | 2024 |
Non-coding variants are a rare cause of recessive developmental disorders in trans with coding variants J Lord, CJ Oquendo, A Martin-Geary, AJM Blakes, E Arciero, S Domcke, ... medRxiv, 2023.06. 23.23291805, 2023 | 2 | 2023 |
sci-ATAC-seq3 S Domcke, AJ Hill, RM Daza, C Trapnell, DA Cusanovich, J Shendure | 1 | 2020 |
Medical Genetics and Genomics Research C Vanlerberghe, AS Jourdain, F Frenois, E Ait-Yahya, M Bamshad, ... | | 2024 |
Influence of DNA methylation on transcription factor binding S Domcke University_of_Basel, 2017 | | 2017 |
Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science 356: eaaj2239 Y Yin, E Morgunova, A Jolma, E Kaasinen, B Sahu, S Khund-Sayeed, ... | | 2017 |