Time-resolved analysis reveals rapid dynamics and broad scope of the CBP/p300 acetylome BT Weinert, T Narita, S Satpathy, B Srinivasan, BK Hansen, C Schölz, ... Cell 174 (1), 231-244. e12, 2018 | 427 | 2018 |
Pantethine rescues a Drosophila model for pantothenate kinase–associated neurodegeneration A Rana, E Seinen, K Siudeja, R Muntendam, B Srinivasan, ... Proceedings of the National Academy of Sciences 107 (15), 6988-6993, 2010 | 176 | 2010 |
Extracellular 4′-phosphopantetheine is a source for intracellular coenzyme A synthesis B Srinivasan, M Baratashvili, M Van Der Zwaag, B Kanon, C Colombelli, ... Nature chemical biology 11 (10), 784-792, 2015 | 142 | 2015 |
Impaired Coenzyme A metabolism affects histone and tubulin acetylation in Drosophila and human cell models of pantothenate kinase associated … K Siudeja, B Srinivasan, L Xu, A Rana, J de Jong, EAA Nollen, ... EMBO molecular medicine 3 (12), 755-766, 2011 | 98 | 2011 |
Coenzyme A, more than ‘just’a metabolic cofactor B Srinivasan, OCM Sibon Biochemical Society transactions 42 (4), 1075-1079, 2014 | 50 | 2014 |
Acetyl-4′-phosphopantetheine is stable in serum and prevents phenotypes induced by pantothenate kinase deficiency I Di Meo, C Colombelli, B Srinivasan, M De Villiers, J Hamada, SY Jeong, ... Scientific reports 7 (1), 11260, 2017 | 32 | 2017 |
Impaired Coenzyme A metabolism affects histone and tubulin acetylation in Drosophila and human cell models of pantothenate kinase associated neurodegeneration. EMBO Mol Med … K Siudeja, B Srinivasan, L Xu, A Rana, J de Jong, EAA Nollen, ... Srp Arh Celok Lek, 3-4, 2020 | 5 | 2020 |
Compositions and methods useful for treating diseases characterized by insufficient pantothenate kinase activity G Kosec, AP Berke, H Petkovic, OCM Sibon, B Srinivasan, SJ Hayflick US Patent App. 17/340,665, 2022 | | 2022 |
Phosphopantetheine compounds alone or in combination with HMG-CoA reductase inhibitors for lowering serum cholesterol and serum triglicerides G Kosec, S Fujs, H Petkovic, OCM Sibon, B Srinivasan US Patent 10,624,908, 2020 | | 2020 |
Compositions and methods useful for treating diseases characterized by insufficient pantothenate kinase activity G Kosec, AP Berke, H Petkovic, OCM Sibon, B Srinivasan, SJ Hayflick US Patent App. 16/309,983, 2019 | | 2019 |
Stable pantetheine derivatives for the treatment of pantothenate kinase associated neurodegeneration (PKAN) and methods for the synthesis of such compounds B Jenko, G Kosec, H Petkovic, AP BERKE, J Pahor, A Cusak, OCM Sibon, ... US Patent 9,963,472, 2018 | | 2018 |
Stable pantetheine derivatives for the treatment of pantothenate kinase associated neurodegeneration (pkan) and methods for the synthesis of such compounds B Jenko, G Kosec, H Petkovic, AP Berke, J Pahor, A Cusak, OCM Sibon, ... US Patent App. 15/850,252, 2018 | | 2018 |
Rerouting'coenzyme A'biosynthesis B Srinivasan | | 2015 |
ALZHEIMER’S J Pahor, A Cusak, OCM Sibon, B Srinivasan Recent Patents on CNS Drug Discovery 10, 65-71, 2015 | | 2015 |
Synthesis and characterization of 4-thiobutyl triphenylphosphonium-pantetheine, a pantetheine derivative. R Lambrechts, B Srinivasan, E Geertsema, G Poelarends, O Sibon, ... American Chemical Science Journal 4 (5), 676-686, 2014 | | 2014 |
Summarizing discussion and conclusion B Srinivasan, OCM Sibon Biochemical Society transactions 42, 1075-1079, 2014 | | 2014 |
Genetic disruption of the Drosophila NUCB1 locus: implications for human disease B Shanthi, B Srinivasan, AK Gopala JOURNAL OF NEUROGENETICS 26, 64-65, 2012 | | 2012 |
Cysteine repeat domains and adjacent sequences determine distinct bone morphogenetic protein modulatory activities of the Drosophila Sog protein (vol 166, pg 1323, 2004) K Yu, KH Kang, P Heine, U Pyati, B Srinivasan, B Biehs, D Kimelman, ... GENETICS 167 (2), 1039-1039, 2004 | | 2004 |