Augmented capacity for peripheral serotonin release in human obesity RL Young, AL Lumsden, AM Martin, G Schober, N Pezos, SS Thazhath, ... International Journal of Obesity 42 (11), 1880-1889, 2018 | 93 | 2018 |
Gut enterochromaffin cells drive visceral pain and anxiety JR Bayrer, J Castro, A Venkataraman, KK Touhara, ND Rossen, ... Nature 616 (7955), 137-142, 2023 | 84 | 2023 |
Activation of pruritogenic TGR5, MrgprA3, and MrgprC11 on colon-innervating afferents induces visceral hypersensitivity J Castro, AM Harrington, TM Lieu, S Garcia-Caraballo, J Maddern, ... JCI insight 4 (20), 2019 | 75 | 2019 |
Histamine induces peripheral and central hypersensitivity to bladder distension via the histamine H1 receptor and TRPV1 L Grundy, A Caldwell, SG Caraballo, A Erickson, G Schober, J Castro, ... American Journal of Physiology-Renal Physiology, 2020 | 65 | 2020 |
Diacylglycerol acyltransferase-1 inhibition enhances intestinal fatty acid oxidation and reduces energy intake in rats [S] G Schober, M Arnold, S Birtles, LK Buckett, G Pacheco-López, ... Journal of lipid research 54 (5), 1369-1384, 2013 | 56 | 2013 |
Intragastric administration of leucine or isoleucine lowers the blood glucose response to a mixed-nutrient drink by different mechanisms in healthy, lean volunteers SS Ullrich, PCE Fitzgerald, G Schober, RE Steinert, M Horowitz, ... The American journal of clinical nutrition 104 (5), 1274-1284, 2016 | 50 | 2016 |
A spider-venom peptide with multitarget activity on sodium and calcium channels alleviates chronic visceral pain in a model of irritable bowel syndrome FC Cardoso, J Castro, L Grundy, G Schober, S Garcia-Caraballo, T Zhao, ... Pain 162 (2), 569-581, 2021 | 37 | 2021 |
Sugar responses of human enterochromaffin cells depend on gut region, sex, and body mass AL Lumsden, AM Martin, EW Sun, G Schober, NJ Isaacs, N Pezos, ... Nutrients 11 (2), 234, 2019 | 27 | 2019 |
Olorinab (APD371), a peripherally acting, highly selective, full agonist of the cannabinoid receptor 2, reduces colitis-induced acute and chronic visceral hypersensitivity in … J Castro, S Garcia-Caraballo, J Maddern, G Schober, A Lumsden, ... Pain 163 (1), e72-e86, 2022 | 26 | 2022 |
Design of a stable cyclic peptide analgesic derived from sunflower seeds that targets the κ-opioid receptor for the treatment of chronic abdominal pain E Muratspahić, N Tomašević, J Koehbach, L Duerrauer, S Hadžić, ... Journal of medicinal chemistry 64 (13), 9042-9055, 2021 | 24 | 2021 |
Pharmacological Inhibition of the Voltage-Gated Sodium Channel NaV1.7 Alleviates Chronic Visceral Pain in a Rodent Model of Irritable Bowel Syndrome Y Jiang, J Castro, LV Blomster, AJ Agwa, J Maddern, G Schober, V Herzig, ... ACS pharmacology & translational science 4 (4), 1362-1378, 2021 | 19 | 2021 |
Contributions of upper gut hormones and motility to the energy intake‐suppressant effects of intraduodenal nutrients in healthy, lean men–a pooled‐data analysis G Schober, K Lange, RE Steinert, AT Hutchison, ND Luscombe‐Marsh, ... Physiological reports 4 (17), e12943, 2016 | 16 | 2016 |
A mouse model of endometriosis that displays vaginal, colon, cutaneous, and bladder sensory comorbidities J Castro, J Maddern, L Grundy, J Manavis, AM Harrington, G Schober, ... The FASEB Journal 35 (4), e21430, 2021 | 15 | 2021 |
Impact of artificial sweeteners on glycaemic control in healthy humans RL Young, NJ Isaacs, G Schober, T Wu, N Cvijanovic, N Pezos, M Bound, ... 53rd Annual Meeting of the European Association for the Study of Diabetes, 2017 | 15 | 2017 |
A gut-intrinsic melanocortin signaling complex augments L-cell secretion in humans EW Sun, EW Iepsen, N Pezos, AL Lumsden, AM Martin, G Schober, ... Gastroenterology 161 (2), 536-547. e2, 2021 | 13 | 2021 |
A syngeneic inoculation mouse model of endometriosis that develops multiple comorbid visceral and cutaneous pain like behaviours J Maddern, L Grundy, A Harrington, G Schober, J Castro, SM Brierley Pain 163 (8), 1622-1635, 2022 | 8 | 2022 |
DGAT-1 inhibition increases plasma glucagon-like peptide-1 (GLP-1) and peptide tyrosine-tyrosine (PYY) levels in response to a high fat (HF) meal in rats G Schober, M Arnold, S Birtles, LK Buckett, AV Turnbull, W Langhans Appetite 57 (S1), S39-S39, 2011 | 5 | 2011 |
Sequence-specific targeting of intrinsically disordered protein regions K Wu, H Jiang, DR Hicks, C Liu, E Muratspahić, TA Ramelot, Y Liu, ... bioRxiv, 2024.07. 15.603480, 2024 | 4 | 2024 |
Sa1078 cannabinoid receptor expression and the effect of Olorinab, a peripherally acting, highly selective, full agonist of the cannabinoid receptor 2 (CB2), in rodents with … J Castro, J Maddern, S Garcia-Caraballo, G Schober, B Lindstrom, ... Gastroenterology 158 (6), S-269, 2020 | 2 | 2020 |
Su1578–chronic intracolonic administration of linaclotide inhibits nociceptive signaling in a mouse model of chronic visceral hypersensitivity J Castro, A Harrington, J Maddern, G Schober, LA Grundy, P Ge, ... Gastroenterology 156 (6), S-570, 2019 | 2 | 2019 |