High tumor mutation burden fails to predict immune checkpoint blockade response across all cancer types DJ McGrail, PG Pilié, NU Rashid, L Voorwerk, M Slagter, M Kok, ... Annals of Oncology 32 (5), 661-672, 2021 | 832 | 2021 |
Sequential therapy with PARP and WEE1 inhibitors minimizes toxicity while maintaining efficacy Y Fang, DJ McGrail, C Sun, M Labrie, X Chen, D Zhang, Z Ju, CP Vellano, ... Cancer cell 35 (6), 851-867. e7, 2019 | 205 | 2019 |
PBRM1 loss defines a nonimmunogenic tumor phenotype associated with checkpoint inhibitor resistance in renal carcinoma XD Liu, W Kong, CB Peterson, DJ McGrail, A Hoang, X Zhang, T Lam, ... Nature communications 11 (1), 2135, 2020 | 165 | 2020 |
Enacting national social distancing policies corresponds with dramatic reduction in COVID19 infection rates DJ McGrail, J Dai, KM McAndrews, R Kalluri PloS one 15 (7), e0236619, 2020 | 161 | 2020 |
The malignancy of metastatic ovarian cancer cells is increased on soft matrices through a mechanosensitive Rho–ROCK pathway DJ McGrail, QMN Kieu, MR Dawson Journal of cell science 127 (12), 2621-2626, 2014 | 145 | 2014 |
Immune checkpoint blockade in glioblastoma: from tumor heterogeneity to personalized treatment VA Arrieta, C Dmello, DJ McGrail, DJ Brat, C Lee-Chang, AB Heimberger, ... The Journal of Clinical Investigation 133 (2), 2023 | 127 | 2023 |
Mesenchymal stem cells induce directional migration of invasive breast cancer cells through TGF-β KM McAndrews, DJ McGrail, N Ravikumar, MR Dawson Scientific reports 5 (1), 16941, 2015 | 104 | 2015 |
Multi-omics analysis reveals neoantigen-independent immune cell infiltration in copy-number driven cancers DJ McGrail, L Federico, Y Li, H Dai, Y Lu, GB Mills, S Yi, SY Lin, N Sahni Nature communications 9 (1), 1317, 2018 | 100 | 2018 |
Proteogenomic Analysis of Salivary Adenoid Cystic Carcinomas Defines Molecular Subtypes and Identifies Therapeutic Targets R Ferrarotto, Y Mitani, DJ McGrail, K Li, TV Karpinets, D Bell, SJ Frank, ... Clinical Cancer Research, 2020 | 99 | 2020 |
Proteome instability is a therapeutic vulnerability in mismatch repair-deficient cancer DJ McGrail, J Garnett, J Yin, H Dai, DJH Shih, TNA Lam, Y Li, C Sun, Y Li, ... Cancer cell 37 (3), 371-386. e12, 2020 | 97 | 2020 |
Characterization of the immune landscape of EGFR-mutant NSCLC identifies CD73/adenosine pathway as a potential therapeutic target X Le, MV Negrao, A Reuben, L Federico, L Diao, D McGrail, M Nilsson, ... Journal of thoracic oncology 16 (4), 583-600, 2021 | 93 | 2021 |
Distinct tumor-infiltrating lymphocyte landscapes are associated with clinical outcomes in localized non-small-cell lung cancer L Federico, DJ McGrail, SE Bentebibel, C Haymaker, A Ravelli, MA Forget, ... Annals of Oncology 33 (1), 42-56, 2022 | 88 | 2022 |
Protection against SARS-CoV-2 by BCG vaccination is not supported by epidemiological analyses J Hensel, KM McAndrews, DJ McGrail, DP Dowlatshahi, VS LeBleu, ... Scientific reports 10 (1), 1-9, 2020 | 83 | 2020 |
Alterations in ovarian cancer cell adhesion drive taxol resistance by increasing microtubule dynamics in a FAK-dependent manner DJ McGrail, NN Khambhati, MX Qi, KS Patel, N Ravikumar, ... Scientific reports 5 (1), 9529, 2015 | 81 | 2015 |
Neoadjuvant chemotherapy increases cytotoxic T cell, tissue resident memory T cell, and B cell infiltration in resectable NSCLC PO Gaudreau, MV Negrao, KG Mitchell, A Reuben, EM Corsini, J Li, ... Journal of Thoracic Oncology 16 (1), 127-139, 2021 | 75 | 2021 |
SNAIL‐induced epithelial‐to‐mesenchymal transition produces concerted biophysical changes from altered cytoskeletal gene expression DJ McGrail, R Mezencev, QMN Kieu, JF McDonald, MR Dawson The FASEB Journal 29 (4), 1280-1289, 2015 | 72 | 2015 |
Poldip2 controls vascular smooth muscle cell migration by regulating focal adhesion turnover and force polarization SR Datla, DJ McGrail, S Vukelic, LP Huff, AN Lyle, L Pounkova, M Lee, ... American Journal of Physiology-Heart and Circulatory Physiology 307 (7 …, 2014 | 63 | 2014 |
Improved prediction of PARP inhibitor response and identification of synergizing agents through use of a novel gene expression signature generation algorithm DJ McGrail, CCJ Lin, J Garnett, Q Liu, W Mo, H Dai, Y Lu, Q Yu, Z Ju, J Yin, ... NPJ systems biology and applications 3 (1), 8, 2017 | 60 | 2017 |
Differential mechanical response of mesenchymal stem cells and fibroblasts to tumor-secreted soluble factors DJ McGrail, D Ghosh, ND Quach, MR Dawson PLoS One 7 (3), e33248, 2012 | 58 | 2012 |
Revealing the determinants of widespread alternative splicing perturbation in cancer Y Li, N Sahni, R Pancsa, DJ McGrail, J Xu, X Hua, ... Cell reports 21 (3), 798-812, 2017 | 56 | 2017 |