GLUT1 inhibition blocks growth of RB1-positive triple negative breast cancer Q Wu, W Ba-Alawi, G Deblois, J Cruickshank, S Duan, E Lima-Fernandes, ... Nature communications 11 (1), 4205, 2020 | 218 | 2020 |
PRMT inhibition induces a viral mimicry response in triple-negative breast cancer Q Wu*, DY Nie*, W Ba-Alawi, YS Ji, ZW Zhang, J Cruickshank, J Haight, ... Nature chemical biology 18 (8), 821-830, 2022 | 76 | 2022 |
A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization D Dilworth, RP Hanley, R Ferreira de Freitas, A Allali-Hassani, M Zhou, ... Nature chemical biology 18 (1), 56-63, 2022 | 68 | 2022 |
Risk of neurological toxicities following the use of different immune checkpoint inhibitor regimens in solid tumors: a systematic review and meta-analysis M Xu, Y Nie, Y Yang, YT Lu, Q Su The neurologist 24 (3), 75-83, 2019 | 50 | 2019 |
Discovery of a potent and selective targeted NSD2 degrader for the reduction of H3K36me2 RP Hanley*, DY Nie*, JR Tabor, F Li, A Sobh, C Xu, NK Barker, D Dilworth, ... Journal of the American Chemical Society 145 (14), 8176-8188, 2023 | 38 | 2023 |
Validating small molecule chemical probes for biological discovery V Vu, MM Szewczyk, DY Nie, CH Arrowsmith, D Barsyte-Lovejoy Annual review of biochemistry 91 (1), 61-87, 2022 | 22 | 2022 |
Recruitment of FBXO22 for targeted degradation of NSD2 DY Nie*, JR Tabor*, J Li, M Kutera, J St-Germain, RP Hanley, E Wolf, ... Nature Chemical Biology, 1-11, 2024 | 17 | 2024 |
TAOK3, a Regulator of LCK–SHP-1 Crosstalk during TCR Signaling JVS Ormonde, Y Nie, J Madrenas Critical Reviews™ in Immunology 39 (1), 2019 | 6 | 2019 |
Altered RNA splicing initiates the viral mimicry response from inverted SINEs following type I PRMT inhibition in Triple-Negative Breast Cancer C Arrowsmith, Q Wu, D Nie, J Cruickshank, J Haight, YS Ji, F Ciamponi, ... | 3 | 2021 |
The Discovery and Characterization of Chemical Degraders of the Histone Methyltransferase NSD2 DY Nie University of Toronto (Canada), 2024 | | 2024 |