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Han-Jou Chen
Han-Jou Chen
Lecturer in Neuroscience, University of York
Подтвержден адрес электронной почты в домене alumni.imperial.ac.uk
Название
Процитировано
Процитировано
Год
Hexanucleotide repeats in ALS/FTD form length-dependent RNA foci, sequester RNA binding proteins, and are neurotoxic
YB Lee, HJ Chen, JN Peres, J Gomez-Deza, J Attig, M Štalekar, ...
Cell reports 5 (5), 1178-1186, 2013
5962013
TDP-43 proteinopathy and ALS: insights into disease mechanisms and therapeutic targets
EL Scotter, HJ Chen, CE Shaw
Neurotherapeutics 12 (2), 352-363, 2015
4272015
Differential roles of the ubiquitin proteasome system and autophagy in the clearance of soluble and aggregated TDP-43 species
EL Scotter, C Vance, AL Nishimura, YB Lee, HJ Chen, H Urwin, ...
Journal of cell science 127 (6), 1263-1278, 2014
3462014
Familial amyotrophic lateral sclerosis is associated with a mutation in D-amino acid oxidase
J Mitchell, P Paul, HJ Chen, A Morris, M Payling, M Falchi, J Habgood, ...
Proceedings of the National Academy of Sciences 107 (16), 7556-7561, 2010
3072010
Characterization of the properties of a novel mutation in VAPB in familial amyotrophic lateral sclerosis
HJ Chen, G Anagnostou, A Chai, J Withers, A Morris, J Adhikaree, ...
Journal of Biological Chemistry 285 (51), 40266-40281, 2010
2252010
The heat shock response plays an important role in TDP-43 clearance: evidence for dysfunction in amyotrophic lateral sclerosis
HJ Chen, JC Mitchell, S Novoselov, J Miller, AL Nishimura, EL Scotter, ...
Brain 139 (5), 1417-1432, 2016
1972016
Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis
BN Smith, SD Topp, C Fallini, H Shibata, HJ Chen, C Troakes, A King, ...
Science translational medicine 9 (388), eaad9157, 2017
1722017
Protective effects of heat shock protein 27 in a model of ALS occur in the early stages of disease progression
PS Sharp, MT Akbar, S Bouri, A Senda, K Joshi, HJ Chen, DS Latchman, ...
Neurobiology of disease 30 (1), 42-55, 2008
1352008
C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity
YB Lee, P Baskaran, J Gomez-Deza, HJ Chen, AL Nishimura, BN Smith, ...
Human molecular genetics 26 (24), 4765-4777, 2017
1012017
RRM adjacent TARDBP mutations disrupt RNA binding and enhance TDP-43 proteinopathy
HJ Chen, SD Topp, HS Hui, E Zacco, M Katarya, C McLoughlin, A King, ...
Brain 142 (12), 3753-3770, 2019
952019
ALS-associated missense and nonsense TBK1 mutations can both cause loss of kinase function
M de Majo, SD Topp, BN Smith, AL Nishimura, HJ Chen, AS Gkazi, ...
Neurobiology of aging 71, 266. e1-266. e10, 2018
872018
Allele-specific knockdown of ALS-associated mutant TDP-43 in neural stem cells derived from induced pluripotent stem cells
AL Nishimura, C Shum, EL Scotter, A Abdelgany, V Sardone, J Wright, ...
PloS one 9 (3), e91269, 2014
652014
Hexanucleotide repeats in ALS/FTD form length-dependent RNA foci, sequester RNA binding proteins, and are neurotoxic. Cell Rep 5: 1178–1186
YB Lee, HJ Chen, JN Peres, J Gomez-Deza, J Attig, M Stalekar, ...
doi. org/10.1016/j. celr ep 201 (3), 10.049, 2013
302013
Renin-angiotensin system polymorphisms in Taiwanese primary vesicoureteral reflux
KP Liu, CY Lin, HJ Chen, CF Wei, GJ Lee-Chen
Podiatry Nephron 19, 594-601, 2004
242004
Mechanisms of TDP-43 proteinopathy onset and propagation
HJ Chen, JC Mitchell
International Journal of Molecular Sciences 22 (11), 6004, 2021
212021
Vianney de Jong JM
BN Smith, SD Topp, C Fallini, H Shibata, HJ Chen, C Troakes, A King, ...
Ten Asbroek A, Redondo AG, Esteban-Pérez J, Tiloca C, Verde F, Duga S, Leigh …, 2017
92017
Mutations in the vesicular trafficking protein Annexin A11 are associated with amyotrophic lateral sclerosis Bradley N. Smith
SD Topp, C Fallini, H Shibata, HJ Chen, C Troakes, A King, N Ticozzi, ...
Science Translational Medicine 9 (388), aad9157, 2017
82017
S ̌ talekar, M
YB Lee, HJ Chen, JN Peres, J Gomez-Deza, J Attig
Troakes, C., Nishimura, AL, Scotter, EL, Vance, C. et al, 1178-1186, 2013
72013
Endoplasmic reticulum (ER) stress in amyotrophic lateral sclerosis (ALS)
HJ Chen, J De Belleroche
Endoplasmic reticulum stress in health and disease, 323-337, 2012
62012
A novel putative familial ALS locus on chromosome 12: D-amino acid oxidase
JS De Belleroche, J Mitchell, P Paul, HJ Chen, A Morris, A Hajitou, ...
Neurology 72 (11), A114-A114, 2009
22009
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Статьи 1–20