| On the temperature dependence of enzyme-catalyzed rates VL Arcus, EJ Prentice, JK Hobbs, AJ Mulholland, MW Van der Kamp, ... Biochemistry 55 (12), 1681-1688, 2016 | 314 | 2016 |
| Biocatalysis with thermostable enzymes: structure and properties of a thermophilic ‘ene’‐reductase related to old yellow enzyme BV Adalbjörnsson, HS Toogood, A Fryszkowska, CR Pudney, TA Jowitt, ... ChemBioChem 11 (2), 197-207, 2010 | 145 | 2010 |
| Fast protein motions are coupled to enzyme H-transfer reactions. CR Pudney, A Guerriero, NJ Baxter, LO Johannissen, JP Waltho, S Hay, ... Journal of the American Chemical Society, 2013 | 104 | 2013 |
| Direct Analysis of Donor− Acceptor Distance and Relationship to Isotope Effects and the Force Constant for Barrier Compression in Enzymatic H-Tunneling Reactions CR Pudney, LO Johannissen, MJ Sutcliffe, S Hay, NS Scrutton Journal of the American Chemical Society 132 (32), 11329-11335, 2010 | 95 | 2010 |
| Evidence to support the hypothesis that promoting vibrations enhance the rate of an enzyme catalyzed H-tunneling reaction CR Pudney, S Hay, C Levy, J Pang, MJ Sutcliffe, D Leys, NS Scrutton Journal of the American Chemical Society 131 (47), 17072-17073, 2009 | 93 | 2009 |
| α-Secondary isotope effects as probes of “tunneling-ready” configurations in enzymatic H-tunneling: Insight from environmentally coupled tunneling models CR Pudney, S Hay, MJ Sutcliffe, NS Scrutton Journal of the American Chemical Society 128 (43), 14053-14058, 2006 | 86 | 2006 |
| Enzyme evolution and the temperature dependence of enzyme catalysis VL Arcus, MW Van Der Kamp, CR Pudney, AJ Mulholland Current Opinion in Structural Biology 65, 96-101, 2020 | 75 | 2020 |
| Specificity of bispecific T cell receptors and antibodies targeting peptide-HLA CJ Holland, RM Crean, JM Pentier, B de Wet, A Lloyd, V Srikannathasan, ... The Journal of clinical investigation 130 (5), 2673-2688, 2020 | 72 | 2020 |
| Barrier compression enhances an enzymatic hydrogen‐transfer reaction S Hay, CR Pudney, TA McGrory, J Pang, MJ Sutcliffe, NS Scrutton Angewandte Chemie International Edition 48 (8), 1452-1454, 2009 | 69 | 2009 |
| Coupled motions direct electrons along human microsomal P450 Chains CR Pudney, B Khara, LO Johannissen, NS Scrutton PLoS biology 9 (12), e1001222, 2011 | 66 | 2011 |
| Mutagenesis of morphinone reductase induces multiple reactive configurations and identifies potential ambiguity in kinetic analysis of enzyme tunneling mechanisms CR Pudney, S Hay, J Pang, C Costello, D Leys, MJ Sutcliffe, NS Scrutton Journal of the American Chemical Society 129 (45), 13949-13956, 2007 | 66 | 2007 |
| The red edge excitation shift phenomenon can be used to unmask protein structural ensembles: implications for NEMO–ubiquitin interactions DAM Catici, HE Amos, Y Yang, JMH van den Elsen, CR Pudney The FEBS journal 283 (12), 2272-2284, 2016 | 61 | 2016 |
| A complete thermodynamic analysis of enzyme turnover links the free energy landscape to enzyme catalysis HBL Jones, SA Wells, EJ Prentice, A Kwok, LL Liang, VL Arcus, ... The FEBS journal 284 (17), 2829-2842, 2017 | 50 | 2017 |
| Gating mechanisms for biological electron transfer: Integrating structure with biophysics reveals the nature of redox control in cytochrome P450 reductase and copper-dependent … NGH Leferink, CR Pudney, S Brenner, DJ Heyes, RR Eady, ... FEBS letters, 2012 | 44 | 2012 |
| Structural and mechanistic aspects of flavoproteins: probes of hydrogen tunnelling S Hay, CR Pudney, NS Scrutton The FEBS Journal 276 (15), 3930-3941, 2009 | 41 | 2009 |
| Are environmentally coupled enzymatic hydrogen tunneling reactions influenced by changes in solution viscosity? S Hay, CR Pudney, MJ Sutcliffe, NS Scrutton Angewandte Chemie 120 (3), 547-550, 2008 | 38 | 2008 |
| Sensing enzyme activation heat capacity at the single-molecule level using gold-nanorod-based optical whispering gallery modes S Subramanian, HBL Jones, S Frustaci, S Winter, MW van der Kamp, ... ACS applied nano materials 4 (5), 4576-4583, 2021 | 36 | 2021 |
| Polyubiquitin drives the molecular interactions of the NF-κB essential modulator (NEMO) by allosteric regulation DAM Catici, JE Horne, GE Cooper, CR Pudney Journal of Biological Chemistry 290 (22), 14130-14139, 2015 | 36 | 2015 |
| Change in heat capacity accurately predicts vibrational coupling in enzyme catalyzed reactions VL Arcus, CR Pudney FEBS Letters, 2015 | 32 | 2015 |
| Bipartite recognition and conformational sampling mechanisms for hydride transfer from nicotinamide coenzyme to FMN in pentaerythritol tetranitrate reductase CR Pudney, S Hay, NS Scrutton The FEBS Journal 276 (17), 4780-4789, 2009 | 30 | 2009 |
