A framework for advancing our understanding of cancer-associated fibroblasts E Sahai, I Astsaturov, E Cukierman, DG DeNardo, M Egeblad, RM Evans, ... Nature Reviews Cancer 20 (3), 174-186, 2020 | 3008 | 2020 |
Macrophages as regulators of tumour immunity and immunotherapy DG DeNardo, B Ruffell Nature Reviews Immunology 19 (6), 369-382, 2019 | 1976 | 2019 |
Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy DG DeNardo, DJ Brennan, E Rexhepaj, B Ruffell, SL Shiao, SF Madden, ... Cancer discovery 1 (1), 54-67, 2011 | 1961 | 2011 |
CD4+ T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages DG DeNardo, JB Barreto, P Andreu, L Vasquez, D Tawfik, N Kolhatkar, ... Cancer cell 16 (2), 91-102, 2009 | 1699 | 2009 |
CSF1/CSF1R blockade reprograms tumor-infiltrating macrophages and improves response to T-cell checkpoint immunotherapy in pancreatic cancer models Y Zhu, BL Knolhoff, MA Meyer, TM Nywening, BL West, J Luo, ... Cancer research 74 (18), 5057-5069, 2014 | 1413 | 2014 |
Targeting tumor-infiltrating macrophages decreases tumor-initiating cells, relieves immunosuppression, and improves chemotherapeutic responses JB Mitchem, DJ Brennan, BL Knolhoff, BA Belt, Y Zhu, DE Sanford, ... Cancer research 73 (3), 1128-1141, 2013 | 1055 | 2013 |
Targeting focal adhesion kinase renders pancreatic cancers responsive to checkpoint immunotherapy H Jiang, S Hegde, BL Knolhoff, Y Zhu, JM Herndon, MA Meyer, ... Nature medicine 22 (8), 851-860, 2016 | 979 | 2016 |
Inflammation and breast cancer. Balancing immune response: crosstalk between adaptive and innate immune cells during breast cancer progression DG DeNardo, LM Coussens Breast cancer research 9, 1-10, 2007 | 866 | 2007 |
Tissue-resident macrophages in pancreatic ductal adenocarcinoma originate from embryonic hematopoiesis and promote tumor progression Y Zhu, JM Herndon, DK Sojka, KW Kim, BL Knolhoff, C Zuo, DR Cullinan, ... Immunity 47 (2), 323-338. e6, 2017 | 809 | 2017 |
Interactions between lymphocytes and myeloid cells regulate pro-versus anti-tumor immunity DG DeNardo, P Andreu, LM Coussens Cancer and Metastasis Reviews 29, 309-316, 2010 | 768 | 2010 |
Targeting tumour-associated macrophages with CCR2 inhibition in combination with FOLFIRINOX in patients with borderline resectable and locally advanced pancreatic cancer: a … TM Nywening, A Wang-Gillam, DE Sanford, BA Belt, RZ Panni, ... The lancet oncology 17 (5), 651-662, 2016 | 750 | 2016 |
Macrophage expression of hypoxia-inducible factor-1α suppresses T-cell function and promotes tumor progression AL Doedens, C Stockmann, MP Rubinstein, D Liao, N Zhang, ... Cancer research 70 (19), 7465-7475, 2010 | 736 | 2010 |
Inflammatory monocyte mobilization decreases patient survival in pancreatic cancer: a role for targeting the CCL2/CCR2 axis DE Sanford, BA Belt, RZ Panni, A Mayer, AD Deshpande, D Carpenter, ... Clinical cancer research 19 (13), 3404-3415, 2013 | 661 | 2013 |
FcRγ activation regulates inflammation-associated squamous carcinogenesis P Andreu, M Johansson, NI Affara, F Pucci, T Tan, S Junankar, L Korets, ... Cancer cell 17 (2), 121-134, 2010 | 650 | 2010 |
Targeting both tumour-associated CXCR2+ neutrophils and CCR2+ macrophages disrupts myeloid recruitment and improves chemotherapeutic responses in pancreatic ductal adenocarcinoma TM Nywening, BA Belt, DR Cullinan, RZ Panni, BJ Han, DE Sanford, ... Gut 67 (6), 1112-1123, 2018 | 463 | 2018 |
Immune cells as mediators of solid tumor metastasis DG DeNardo, M Johansson, LM Coussens Cancer and Metastasis Reviews 27, 11-18, 2008 | 462 | 2008 |
The human tumor atlas network: charting tumor transitions across space and time at single-cell resolution O Rozenblatt-Rosen, A Regev, P Oberdoerffer, T Nawy, A Hupalowska, ... Cell 181 (2), 236-249, 2020 | 459 | 2020 |
Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis MK Ruhland, AJ Loza, AH Capietto, X Luo, BL Knolhoff, KC Flanagan, ... Nature communications 7 (1), 11762, 2016 | 437 | 2016 |
Dendritic cell paucity leads to dysfunctional immune surveillance in pancreatic cancer S Hegde, VE Krisnawan, BH Herzog, C Zuo, MA Breden, BL Knolhoff, ... Cancer cell 37 (3), 289-307. e9, 2020 | 396 | 2020 |
MRI of tumor-associated macrophages with clinically applicable iron oxide nanoparticles HE Daldrup-Link, D Golovko, B Ruffell, DG DeNardo, R Castaneda, ... Clinical Cancer Research 17 (17), 5695-5704, 2011 | 349 | 2011 |