| Xenobiotic, bile acid, and cholesterol transporters: function and regulation CD Klaassen, LM Aleksunes Pharmacological reviews 62 (1), 1-96, 2010 | 953 | 2010 |
| Oxidative and electrophilic stress induces multidrug resistance–associated protein transporters via the nuclear factor‐E2–related factor‐2 transcriptional pathway JM Maher, MZ Dieter, LM Aleksunes, AL Slitt, G Guo, Y Tanaka, ... Hepatology 46 (5), 1597-1610, 2007 | 383 | 2007 |
| Emerging role of Nrf2 in protecting against hepatic and gastrointestinal disease LM Aleksunes, JE Manautou Toxicologic pathology 35 (4), 459-473, 2007 | 343 | 2007 |
| Introducing the “TCDD-inducible AhR-Nrf2 gene battery” RL Yeager, SA Reisman, LM Aleksunes, CD Klaassen Toxicological sciences 111 (2), 238-246, 2009 | 314 | 2009 |
| Coordinated regulation of hepatic phase I and II drug-metabolizing genes and transporters using AhR-, CAR-, PXR-, PPARα-, and Nrf2-null mice LM Aleksunes, CD Klaassen Drug Metabolism and Disposition 40 (7), 1366-1379, 2012 | 292 | 2012 |
| NF-E2-related factor 2 inhibits lipid accumulation and oxidative stress in mice fed a high-fat diet Y Tanaka, LM Aleksunes, RL Yeager, MA Gyamfi, N Esterly, GL Guo, ... Journal of Pharmacology and Experimental Therapeutics 325 (2), 655-664, 2008 | 292 | 2008 |
| Inherited disorders of bilirubin clearance N Memon, BI Weinberger, T Hegyi, LM Aleksunes Pediatric research 79 (3), 378-386, 2016 | 265 | 2016 |
| Antibacterial spectrum of a novel des-fluoro (6) quinolone, BMS-284756 JC Fung-Tomc, B Minassian, B Kolek, E Huczko, L Aleksunes, T Stickle, ... Antimicrobial Agents and Chemotherapy 44 (12), 3351-3356, 2000 | 242 | 2000 |
| Transcriptional regulation of renal cytoprotective genes by Nrf2 and its potential use as a therapeutic target to mitigate cisplatin-induced nephrotoxicity LM Aleksunes, MJ Goedken, CE Rockwell, J Thomale, JE Manautou, ... Journal of Pharmacology and Experimental Therapeutics 335 (1), 2-12, 2010 | 219 | 2010 |
| Oleanolic acid activates Nrf2 and protects from acetaminophen hepatotoxicity via Nrf2-dependent and Nrf2-independent processes SA Reisman, LM Aleksunes, CD Klaassen Biochemical pharmacology 77 (7), 1273-1282, 2009 | 217 | 2009 |
| Advancing computer-aided drug discovery (CADD) by big data and data-driven machine learning modeling L Zhao, HL Ciallella, LM Aleksunes, H Zhu Drug discovery today 25 (9), 1624-1638, 2020 | 191 | 2020 |
| Human ontogeny of drug transporters: review and recommendations of the pediatric transporter working group KLR Brouwer, LM Aleksunes, B Brandys, GP Giacoia, G Knipp, ... Clinical Pharmacology & Therapeutics 98 (3), 266-287, 2015 | 189 | 2015 |
| Induction of Mrp3 and Mrp4 transporters during acetaminophen hepatotoxicity is dependent on Nrf2 LM Aleksunes, AL Slitt, JM Maher, LM Augustine, MJ Goedken, JY Chan, ... Toxicology and applied pharmacology 226 (1), 74-83, 2008 | 186 | 2008 |
| Placental drug transport‐on‐a‐chip: a microengineered in vitro model of transporter‐mediated drug efflux in the human placental barrier C Blundell, YS Yi, L Ma, ER Tess, MJ Farrell, A Georgescu, LM Aleksunes, ... Advanced healthcare materials 7 (2), 1700786, 2018 | 171 | 2018 |
| Differential expression of mouse hepatic transporter genes in response to acetaminophen and carbon tetrachloride LM Aleksunes, AM Slitt, NJ Cherrington, MS Thibodeau, CD Klaassen, ... Toxicological Sciences 83 (1), 44-52, 2005 | 155 | 2005 |
| Nuclear factor erythroid 2-related factor 2 deletion impairs glucose tolerance and exacerbates hyperglycemia in type 1 diabetic mice LM Aleksunes, SA Reisman, RL Yeager, MJ Goedken, CD Klaassen Journal of Pharmacology and Experimental Therapeutics 333 (1), 140-151, 2010 | 146 | 2010 |
| Drug-metabolizing enzyme and transporter expression in a mouse model of diabetes and obesity Q Cheng, LM Aleksunes, JE Manautou, NJ Cherrington, GL Scheffer, ... Molecular pharmaceutics 5 (1), 77-91, 2008 | 142 | 2008 |
| Xenobiotic transporters and kidney injury B George, D You, MS Joy, LM Aleksunes Advanced drug delivery reviews 116, 73-91, 2017 | 140 | 2017 |
| ANIT-induced intrahepatic cholestasis alters hepatobiliary transporter expression via Nrf2-dependent and independent signaling Y Tanaka, LM Aleksunes, YJ Cui, CD Klaassen Toxicological sciences 108 (2), 247-257, 2009 | 139 | 2009 |
| Nrf2-and PPARα-mediated regulation of hepatic Mrp transporters after exposure to perfluorooctanoic acid and perfluorodecanoic acid JM Maher, LM Aleksunes, MZ Dieter, Y Tanaka, JM Peters, JE Manautou, ... Toxicological sciences 106 (2), 319-328, 2008 | 133 | 2008 |
