Подписаться
Rakan El-Mayta
Rakan El-Mayta
Department of Medicine, University of Pennsylvania
Подтвержден адрес электронной почты в домене sas.upenn.edu
Название
Процитировано
Процитировано
Год
Scalable mRNA and siRNA lipid nanoparticle production using a parallelized microfluidic device
SJ Shepherd, CC Warzecha, S Yadavali, R El-Mayta, MG Alameh, ...
Nano Letters 21 (13), 5671-5680, 2021
1982021
Helper lipid structure influences protein adsorption and delivery of lipid nanoparticles to spleen and liver
R Zhang, R El-Mayta, TJ Murdoch, CC Warzecha, MM Billingsley, ...
Biomaterials Science 9 (4), 1449-1463, 2021
1712021
Ionizable lipid nanoparticles encapsulating barcoded mRNA for accelerated in vivo delivery screening
PPG Guimaraes, R Zhang, R Spektor, M Tan, A Chung, MM Billingsley, ...
Journal of Controlled Release 316, 404-417, 2019
1662019
Ligand-tethered lipid nanoparticles for targeted RNA delivery to treat liver fibrosis
X Han, N Gong, L Xue, MM Billingsley, R El-Mayta, SJ Shepherd, ...
Nature Communications 14 (1), 75, 2023
872023
In vivo mRNA CAR T cell engineering via targeted ionizable lipid nanoparticles with extrahepatic tropism
MM Billingsley, N Gong, AJ Mukalel, AS Thatte, R El‐Mayta, SK Patel, ...
Small 20 (11), 2304378, 2024
512024
Throughput-scalable manufacturing of SARS-CoV-2 mRNA lipid nanoparticle vaccines
SJ Shepherd, X Han, AJ Mukalel, R El-Mayta, AS Thatte, J Wu, MS Padilla, ...
Proceedings of the National Academy of Sciences 120 (33), e2303567120, 2023
452023
Doxorubicin-conjugated siRNA lipid nanoparticles for combination cancer therapy
K Butowska, X Han, N Gong, R El-Mayta, RM Haley, L Xue, W Zhong, ...
Acta Pharmaceutica Sinica B 13 (4), 1429-1437, 2023
412023
Delivery technologies to engineer natural killer cells for cancer immunotherapy
R El-Mayta, Z Zhang, AG Hamilton, MJ Mitchell
Cancer Gene Therapy 28 (9), 947-959, 2021
372021
High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models
L Xue, AG Hamilton, G Zhao, Z Xiao, R El-Mayta, X Han, N Gong, X Xiong, ...
Nature Communications 15 (1), 1884, 2024
362024
In situ PEGylation of CAR T cells alleviates cytokine release syndrome and neurotoxicity
N Gong, X Han, L Xue, R El-Mayta, AE Metzloff, MM Billingsley, ...
Nature Materials 22 (12), 1571-1580, 2023
322023
A Nanoparticle Platform for Accelerated In Vivo Oral Delivery Screening of Nucleic Acids
R El‐Mayta, R Zhang, SJ Shepherd, F Wang, MM Billingsley, V Dudkin, ...
Advanced Therapeutics 4 (1), 2000111, 2021
312021
In vivo bone marrow microenvironment siRNA delivery using lipid–polymer nanoparticles for multiple myeloma therapy
PPG Guimarães, CG Figueroa-Espada, RS Riley, N Gong, L Xue, ...
Proceedings of the National Academy of Sciences 120 (25), e2215711120, 2023
302023
Enhancing in situ cancer vaccines using delivery technologies
N Gong, MG Alameh, R El-Mayta, L Xue, D Weissman, MJ Mitchell
Nature Reviews Drug Discovery 23 (8), 607-625, 2024
202024
Bile acid-containing lipid nanoparticles enhance extrahepatic mRNA delivery
SK Patel, MM Billingsley, AJ Mukalel, AS Thatte, AG Hamilton, N Gong, ...
Theranostics 14 (1), 1, 2024
202024
In situ combinatorial synthesis of degradable branched lipidoids for systemic delivery of mRNA therapeutics and gene editors
X Han, J Xu, Y Xu, MG Alameh, L Xue, N Gong, R El-Mayta, R Palanki, ...
Nature Communications 15 (1), 1762, 2024
162024
Endothelial plasticity drives aberrant vascularization and impedes cardiac repair after myocardial infarction
M Huang, F Yang, D Zhang, M Lin, H Duan, R El-Mayta, L Zhang, L Qin, ...
Nature Cardiovascular Research 1 (4), 372-388, 2022
142022
Testing the in vitro and in vivo efficiency of mRNA-lipid nanoparticles formulated by microfluidic mixing
R El-Mayta, MS Padilla, MM Billingsley, X Han, MJ Mitchell
Journal of Visualized Experiments, 2023
122023
Fast and facile synthesis of amidine-incorporated degradable lipids for versatile mRNA delivery in vivo
X Han, MG Alameh, N Gong, L Xue, M Ghattas, G Bojja, J Xu, G Zhao, ...
Nature chemistry 16 (10), 1687-1697, 2024
102024
An immunosuppressive vascular niche drives macrophage polarization and immunotherapy resistance in glioblastoma
F Yang, MN Akhtar, D Zhang, R El-Mayta, J Shin, JF Dorsey, L Zhang, ...
Science Advances 10 (9), eadj4678, 2024
92024
High-Throughput In Vivo Screening Identifies Differential Influences on mRNA Lipid Nanoparticle Immune Cell Delivery by Administration Route
AG Hamilton, KL Swingle, AS Thatte, AJ Mukalel, HC Safford, ...
ACS Nano, 2024
72024
В данный момент система не может выполнить эту операцию. Повторите попытку позднее.
Статьи 1–20