| The roles of structural dynamics in the cellular functions of RNAs LR Ganser, ML Kelly, D Herschlag, HM Al-Hashimi Nature reviews Molecular cell biology 20 (8), 474-489, 2019 | 479 | 2019 |
| TDP-43 represses cryptic exon inclusion in the FTD–ALS gene UNC13A XR Ma, M Prudencio, Y Koike, SC Vatsavayai, G Kim, F Harbinski, ... Nature 603 (7899), 124-130, 2022 | 340 | 2022 |
| High-performance virtual screening by targeting a high-resolution RNA dynamic ensemble LR Ganser, J Lee, A Rangadurai, DK Merriman, ML Kelly, AD Kansal, ... Nature structural & molecular biology 25 (5), 425-434, 2018 | 106 | 2018 |
| Glucose starvation inhibits autophagy via vacuolar hydrolysis and induces plasma membrane internalization by down-regulating recycling MJ Lang, JY Martinez-Marquez, DC Prosser, LR Ganser, D Buelto, ... Journal of Biological Chemistry 289 (24), 16736-16747, 2014 | 97 | 2014 |
| Amiloride as a new RNA-binding scaffold with activity against HIV-1 TAR NN Patwardhan, LR Ganser, GJ Kapral, CS Eubanks, J Lee, ... MedChemComm 8 (5), 1022-1036, 2017 | 92 | 2017 |
| Poly (ADP-ribose) drives condensation of FUS via a transient interaction K Rhine, M Dasovich, J Yoniles, M Badiee, S Skanchy, LR Ganser, Y Ge, ... Molecular cell 82 (5), 969-985. e11, 2022 | 65 | 2022 |
| Methods to study phase-separated condensates and the underlying molecular interactions LR Ganser, S Myong Trends in biochemical sciences 45 (11), 1004, 2020 | 53 | 2020 |
| Resolving sugar puckers in RNA excited states exposes slow modes of repuckering dynamics MC Clay, LR Ganser, DK Merriman, HM Al-Hashimi Nucleic acids research 45 (14), e134-e134, 2017 | 51 | 2017 |
| Development and application of aromatic [13C, 1H] SOFAST-HMQC NMR experiment for nucleic acids B Sathyamoorthy, J Lee, I Kimsey, LR Ganser, H Al-Hashimi Journal of biomolecular NMR 60, 77-83, 2014 | 51 | 2014 |
| Probing RNA conformational equilibria within the functional cellular context LR Ganser, CC Chu, HP Bogerd, ML Kelly, BR Cullen, HM Al-Hashimi Cell reports 30 (8), 2472-2480. e4, 2020 | 39 | 2020 |
| RNA conformational propensities determine cellular activity ML Ken, R Roy, A Geng, LR Ganser, A Manghrani, BR Cullen, ... Nature 617 (7962), 835-841, 2023 | 35 | 2023 |
| Demonstration that small molecules can bind and stabilize low-abundance short-lived RNA excited conformational states LR Ganser, ML Kelly, NN Patwardhan, AE Hargrove, HM Al-Hashimi Journal of molecular biology 432 (4), 1297-1304, 2020 | 32 | 2020 |
| Understanding the characteristics of nonspecific binding of drug-like compounds to canonical stem–loop RNAs and their implications for functional cellular assays ML Kelly, CC Chu, H Shi, LR Ganser, HP Bogerd, K Huynh, Y Hou, ... Rna 27 (1), 12-26, 2021 | 23 | 2021 |
| Switch-like compaction of poly (ADP-ribose) upon cation binding M Badiee, AL Kenet, LR Ganser, T Paul, S Myong, AKL Leung Proceedings of the National Academy of Sciences 120 (19), e2215068120, 2023 | 14 | 2023 |
| An RNA excited conformational state at atomic resolution A Geng, L Ganser, R Roy, H Shi, S Pratihar, DA Case, HM Al-Hashimi Nature Communications 14 (1), 8432, 2023 | 11 | 2023 |
| HIV-1 leader RNA dimeric interface revealed by NMR LR Ganser, HM Al-Hashimi Proceedings of the National Academy of Sciences 113 (47), 13263-13265, 2016 | 7 | 2016 |
| Nucleation and dissolution mechanism underlying amyotrophic lateral sclerosis/frontotemporal lobar dementia-linked fused in sarcoma condensates NA Djaja, MT Chang, FR Beinart, VM Morris, LR Ganser, S Myong Iscience 26 (4), 2023 | 6 | 2023 |
| Single-molecule fluorescence methods to study protein-RNA interactions underlying biomolecular condensates LR Ganser, Y Ge, S Myong Phase-Separated Biomolecular Condensates: Methods and Protocols, 149-160, 2022 | 5 | 2022 |
| An RNA tertiary switch by modifying how helices are tethered LR Ganser, AM Mustoe, HM Al-Hashimi Genome biology 15, 1-3, 2014 | 5 | 2014 |
| The roles of FUS-RNA binding domain and low complexity domain in RNA-dependent phase separation LR Ganser, AG Niaki, X Yuan, E Huang, D Deng, NA Djaja, Y Ge, A Craig, ... Structure 32 (2), 177-187. e5, 2024 | 4 | 2024 |
