| Efficacy and safety of abemaciclib, an inhibitor of CDK4 and CDK6, for patients with breast cancer, non–small cell lung cancer, and other solid tumors A Patnaik, LS Rosen, SM Tolaney, AW Tolcher, JW Goldman, L Gandhi, ... Cancer discovery 6 (7), 740-753, 2016 | 722 | 2016 |
| Brain exposure of two selective dual CDK4 and CDK6 inhibitors and the antitumor activity of CDK4 and CDK6 inhibition in combination with temozolomide in an intracranial … TJ Raub, GN Wishart, P Kulanthaivel, BA Staton, RT Ajamie, GA Sawada, ... Drug Metabolism and Disposition 43 (9), 1360-1371, 2015 | 283 | 2015 |
| Balanol: a novel and potent inhibitor of protein kinase C from the fungus Verticillium balanoides P Kulanthaivel, YF Hallock, C Boros, SM Hamilton, WP Janzen, LM Ballas, ... Journal of the American Chemical Society 115 (14), 6452-6453, 1993 | 276 | 1993 |
| Selective metabolism of vincristine in vitro by CYP3A5 JB Dennison, P Kulanthaivel, RJ Barbuch, JL Renbarger, WJ Ehlhardt, ... Drug metabolism and disposition 34 (8), 1317-1327, 2006 | 214 | 2006 |
| A panel of cytochrome P450 BM3 variants to produce drug metabolites and diversify lead compounds AM Sawayama, MMY Chen, P Kulanthaivel, MS Kuo, H Hemmerle, ... Chemistry–A European Journal 15 (43), 11723-11729, 2009 | 209 | 2009 |
| Metabolism of capsaicin by cytochrome P450 produces novel dehydrogenated metabolites and decreases cytotoxicity to lung and liver cells CA Reilly, WJ Ehlhardt, DA Jackson, P Kulanthaivel, AE Mutlib, RJ Espina, ... Chemical research in toxicology 16 (3), 336-349, 2003 | 151 | 2003 |
| Expression of a cocaine-sensitive norepinephrine transporter in the human placental syncytiotrophoblast S Ramamoorthy, PD Prasad, P Kulanthaivel, FH Leibach, RD Blakely, ... Biochemistry 32 (5), 1346-1353, 1993 | 149 | 1993 |
| Discovery of cercosporamide, a known antifungal natural product, as a selective Pkc1 kinase inhibitor through high-throughput screening A Sussman, K Huss, LC Chio, S Heidler, M Shaw, D Ma, G Zhu, ... Eukaryotic cell 3 (4), 932-943, 2004 | 130 | 2004 |
| Novel lipoglycopeptides as inhibitors of bacterial signal peptidase I P Kulanthaivel, AJ Kreuzman, MA Strege, MD Belvo, TA Smitka, ... Journal of Biological Chemistry 279 (35), 36250-36258, 2004 | 123 | 2004 |
| A first-in-human phase I study of the oral p38 MAPK inhibitor, ralimetinib (LY2228820 dimesylate), in patients with advanced cancer A Patnaik, P Haluska, AW Tolcher, C Erlichman, KP Papadopoulos, ... Clinical Cancer Research 22 (5), 1095-1102, 2016 | 112 | 2016 |
| Transport of taurine and its regulation by protein kinase C in the JAR human placental choriocarcinoma cell line P Kulanthaivel, DR Cool, S Ramamoorthy, VB Mahesh, FH Leibach, ... Biochemical journal 277 (1), 53-58, 1991 | 106 | 1991 |
| Abemaciclib inhibits renal tubular secretion without changing glomerular filtration rate JC Chappell, PK Turner, YA Pak, J Bacon, AY Chiang, J Royalty, SD Hall, ... Clinical Pharmacology & Therapeutics 105 (5), 1187-1195, 2019 | 93 | 2019 |
| A first-in-human phase I study of the CDK4/6 inhibitor, LY2835219, for patients with advanced cancer. G Shapiro, LS Rosen, AW Tolcher, JW Goldman, L Gandhi, ... Journal of Clinical Oncology 31 (15_suppl), 2500-2500, 2013 | 89 | 2013 |
| ent-Kauranes and other constituents of three Helianthus species W Herz, P Kulanthaivel, K Watanabe Phytochemistry 22 (9), 2021-2025, 1983 | 86 | 1983 |
| A natural product ligand of the oxysterol receptor, liver X receptor KS Bramlett, KA Houck, KM Borchert, MS Dowless, P Kulanthaivel, ... The journal of Pharmacology and experimental Therapeutics 307 (1), 291-296, 2003 | 84 | 2003 |
| A population pharmacokinetic and pharmacodynamic analysis of abemaciclib in a phase I clinical trial in cancer patients SC Tate, AK Sykes, P Kulanthaivel, EM Chan, PK Turner, DM Cronier Clinical pharmacokinetics 57, 335-344, 2018 | 80 | 2018 |
| Naturally Occurring Protein Kinase C Inhibitors; II1. Isolation of Oligomeric Stilbenes from Caragana Sinica2 P Kulanthaivel, WP Janzen, LM Ballas, JB Jiang, CQ Hu, JW Darges, ... Planta medica 61 (01), 41-44, 1995 | 77 | 1995 |
| New antiproliferative and antiinflammatory 9, 11-secosterols from the gorgonian Pseudopterogorgia sp H He, P Kulanthaivel, BJ Baker, K Kalter, J Darges, D Cofield, L Wolff, ... Tetrahedron 51 (1), 51-58, 1995 | 77 | 1995 |
| The Na (+)-H+ exchanger of the placental brush-border membrane is pharmacologically distinct from that of the renal brush-border membrane. P Kulanthaivel, FH Leibach, VB Mahesh, EJ Cragoe Jr, V Ganapathy Journal of Biological Chemistry 265 (3), 1249-1252, 1990 | 69 | 1990 |
| Stereochemistry of strictic acid and related furano-diterpenes from Conyza japonica and Grangea maderaspatana UC Pandey, AK Singhal, NC Barua, RP Sharma, JN Baruah, K Watanabe, ... Phytochemistry 23 (2), 391-397, 1984 | 69 | 1984 |
