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Paul R Thompson
Paul R Thompson
Подтвержден адрес электронной почты в домене umassmed.edu
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NETs are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritis
R Khandpur, C Carmona-Rivera, A Vivekanandan-Giri, A Gizinski, ...
Science translational medicine 5 (178), 178ra40-178ra40, 2013
14412013
Diverse stimuli engage different neutrophil extracellular trap pathways
EF Kenny, A Herzig, R Krüger, A Muth, S Mondal, PR Thompson, ...
Elife 6, e24437, 2017
7662017
Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation
HD Lewis, J Liddle, JE Coote, SJ Atkinson, MD Barker, BD Bax, KL Bicker, ...
Nature chemical biology 11 (3), 189-191, 2015
7282015
The structural basis of protein acetylation by the p300/CBP transcriptional coactivator
X Liu, L Wang, K Zhao, PR Thompson, Y Hwang, R Marmorstein, PA Cole
Nature 451 (7180), 846-850, 2008
5222008
Regulation of the p300 HAT domain via a novel activation loop
PR Thompson, D Wang, L Wang, M Fulco, N Pediconi, D Zhang, W An, ...
Nature structural & molecular biology 11 (4), 308-315, 2004
5062004
Succination inactivates gasdermin D and blocks pyroptosis
F Humphries, L Shmuel-Galia, N Ketelut-Carneiro, S Li, B Wang, ...
Science 369 (6511), 1633-1637, 2020
4982020
Peptidylarginine deiminase inhibition reduces vascular damage and modulates innate immune responses in murine models of atherosclerosis
JS Knight, W Luo, AA O’Dell, S Yalavarthi, W Zhao, V Subramanian, ...
Circulation research 114 (6), 947-956, 2014
4412014
Peptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus-prone MRL/lpr mice
JS Knight, V Subramanian, AA O'Dell, S Yalavarthi, W Zhao, CK Smith, ...
Annals of the rheumatic diseases 74 (12), 2199-2206, 2015
4382015
Activation of PAD4 in NET formation
AS Rohrbach, DJ Slade, PR Thompson, KA Mowen
Frontiers in immunology 3, 360, 2012
4022012
Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupus
JS Knight, W Zhao, W Luo, V Subramanian, AA O’Dell, S Yalavarthi, ...
The Journal of clinical investigation 123 (7), 2981-2993, 2013
3962013
Inhibitors and Inactivators of Protein Arginine Deiminase 4:  Functional and Structural Characterization,
Y Luo, K Arita, M Bhatia, B Knuckley, YH Lee, MR Stallcup, M Sato, ...
Biochemistry 45 (39), 11727-11736, 2006
3462006
N-α-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine amide, a protein arginine deiminase inhibitor, reduces the severity of murine collagen-induced arthritis
VC Willis, AM Gizinski, NK Banda, CP Causey, B Knuckley, KN Cordova, ...
The Journal of Immunology 186 (7), 4396-4404, 2011
3302011
Chemical biology of protein arginine modifications in epigenetic regulation
J Fuhrmann, KW Clancy, PR Thompson
Chemical reviews 115 (11), 5413-5461, 2015
3182015
Protein arginine deiminases and associated citrullination: physiological functions and diseases associated with dysregulation
E E Witalison, P R Thompson, L J Hofseth
Current drug targets 16 (7), 700-710, 2015
3162015
Structure of an enzyme required for aminoglycoside antibiotic resistance reveals homology to eukaryotic protein kinases
WC Hon, GA McKay, PR Thompson, RM Sweet, DSC Yang, GD Wright, ...
Cell 89 (6), 887-895, 1997
2981997
Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis
C Carmona-Rivera, PM Carlucci, E Moore, N Lingampalli, ...
Science immunology 2 (10), eaag3358, 2017
2852017
Protein arginine deiminase 4 (PAD4): Current understanding and future therapeutic potential
J Jones, C Causey, B Knuckley, JL Slack-Noyes, PR Thompson
Current opinion in drug discovery & development 12 (5), 616, 2009
2832009
Regulation of p53 target gene expression by peptidylarginine deiminase 4
P Li, H Yao, Z Zhang, M Li, Y Luo, PR Thompson, DS Gilmour, Y Wang
Molecular and cellular biology 28 (15), 4745-4758, 2008
2822008
The protein arginine deiminases: Structure, function, inhibition, and disease
KL Bicker, PR Thompson
Biopolymers 99 (2), 155-163, 2013
2762013
Kinetic characterization of protein arginine deiminase 4: a transcriptional corepressor implicated in the onset and progression of rheumatoid arthritis
PL Kearney, M Bhatia, NG Jones, L Yuan, MC Glascock, KL Catchings, ...
Biochemistry 44 (31), 10570-10582, 2005
2502005
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