Self-assembling cages from coiled-coil peptide modules JM Fletcher, RL Harniman, FRH Barnes, AL Boyle, A Collins, J Mantell, ... Science 340 (6132), 595-599, 2013 | 559 | 2013 |
A Basis Set of de Novo Coiled-Coil Peptide Oligomers for Rational Protein Design and Synthetic Biology JM Fletcher, AL Boyle, M Bruning, GJ Bartlett, TL Vincent, NR Zaccai, ... ACS synthetic biology 1 (6), 240-250, 2012 | 326 | 2012 |
Engineered synthetic scaffolds for organizing proteins within the bacterial cytoplasm MJ Lee, J Mantell, L Hodgson, D Alibhai, JM Fletcher, IR Brown, S Frank, ... Nature chemical biology 14 (2), 142-147, 2018 | 155 | 2018 |
Bioorthogonal dual functionalization of self-assembling peptide fibers ZN Mahmoud, SB Gunnoo, AR Thomson, JM Fletcher, DN Woolfson Biomaterials 32 (15), 3712-3720, 2011 | 79 | 2011 |
Design of a conformationally defined and proteolytically stable circular mimetic of brain-derived neurotrophic factor JM Fletcher, CJ Morton, RA Zwar, SS Murray, PD O'Leary, RA Hughes Journal of Biological Chemistry 283 (48), 33375-33383, 2008 | 69 | 2008 |
Novel monocyclic and bicyclic loop mimetics of brain‐derived neurotrophic factor JM Fletcher, RA Hughes Journal of peptide science: an official publication of the European Peptide …, 2006 | 69 | 2006 |
Decorating self-assembled peptide cages with proteins JF Ross, A Bridges, JM Fletcher, D Shoemark, D Alibhai, HEV Bray, ... ACS nano 11 (8), 7901-7914, 2017 | 65 | 2017 |
Modified low molecular weight cyclic peptides as mimetics of BDNF with improved potency, proteolytic stability and transmembrane passage in vitro JM Fletcher, RA Hughes Bioorganic & medicinal chemistry 17 (7), 2695-2702, 2009 | 53 | 2009 |
De novo targeting to the cytoplasmic and luminal side of bacterial microcompartments MJ Lee, J Mantell, IR Brown, JM Fletcher, P Verkade, RW Pickersgill, ... Nature communications 9 (1), 3413, 2018 | 50 | 2018 |
De novo coiled-coil peptides as scaffolds for disrupting protein–protein interactions JM Fletcher, KA Horner, GJ Bartlett, GG Rhys, AJ Wilson, DN Woolfson Chemical science 9 (39), 7656-7665, 2018 | 46 | 2018 |
Beyond icosahedral symmetry in packings of proteins in spherical shells M Mosayebi, DK Shoemark, JM Fletcher, RB Sessions, N Linden, ... Proceedings of the National Academy of Sciences 114 (34), 9014-9019, 2017 | 46 | 2017 |
N@a and N@d: Oligomer and Partner Specification by Asparagine in Coiled-Coil Interfaces JM Fletcher, GJ Bartlett, AL Boyle, JJ Danon, LE Rush, AN Lupas, ... ACS Chemical Biology 12 (2), 528-538, 2017 | 45 | 2017 |
Designed coiled coils promote folding of a recombinant bacterial collagen A Yoshizumi, JM Fletcher, Z Yu, AV Persikov, GJ Bartlett, AL Boyle, ... Journal of Biological Chemistry 286 (20), 17512-17520, 2011 | 45 | 2011 |
De novo design of a reversible phosphorylation-dependent switch for membrane targeting L Harrington, JM Fletcher, T Heermann, DN Woolfson, P Schwille Nature Communications 12 (1), 1472, 2021 | 34 | 2021 |
Synthesis of Stapled β3-Peptides through Ring-Closing Metathesis YE Bergman, MP Del Borgo, RD Gopalan, S Jalal, SE Unabia, ... Organic Letters 11 (19), 4438-4440, 2009 | 31 | 2009 |
Interactions of HIV‐1 Antibodies 2F5 and 4E10 with a gp41 Epitope Prebound to Host and Viral Membrane Model Systems AS Veiga, LK Pattenden, JM Fletcher, MARB Castanho, MI Aguilar Chembiochem 10 (6), 1032-1044, 2009 | 30 | 2009 |
A novel approach to the regioselective synthesis of a disulfide-linked heterodimeric bicyclic peptide mimetic of brain-derived neurotrophic factor JM Fletcher, RA Hughes Tetrahedron letters 45 (38), 6999-7001, 2004 | 25 | 2004 |
Differential sensing with arrays of de novo designed peptide assemblies WM Dawson, KL Shelley, JM Fletcher, DA Scott, L Lombardi, GG Rhys, ... Nature Communications 14 (1), 383, 2023 | 20 | 2023 |
Bioinspired silicification reveals structural detail in self-assembled peptide cages JM Galloway, L Senior, JM Fletcher, JL Beesley, LR Hodgson, ... Acs Nano 12 (2), 1420-1432, 2017 | 20 | 2017 |
Self-assembling peptide cages from coiled-coil peptide modules D Woolfson, P Booth, J Fletcher, R Sessions, N Linden US Patent 9,562,074, 2017 | 1 | 2017 |