| Highly Efficient UV Organic Light‐Emitting Devices Based on Bi (9, 9‐diarylfluorene) s TC Chao, YT Lin, CY Yang, TS Hung, HC Chou, CC Wu, KT Wong Advanced Materials 17 (8), 992-996, 2005 | 294 | 2005 |
| Glucose-responsive insulin activity by covalent modification with aliphatic phenylboronic acid conjugates DHC Chou, MJ Webber, BC Tang, AB Lin, LS Thapa, D Deng, JV Truong, ... Proceedings of the National Academy of Sciences 112 (8), 2401-2406, 2015 | 266 | 2015 |
| A Thiol–Ene Coupling Approach to Native Peptide Stapling and Macrocyclization Y Wang, DHC Chou Angewandte Chemie International Edition 54 (37), 10931-10934, 2015 | 200 | 2015 |
| Selective N-terminal functionalization of native peptides and proteins D Hung-ChieháChou Chemical Science 8 (4), 2717-2722, 2017 | 149 | 2017 |
| Inhibition of Histone Deacetylase 3 Protects Beta Cells from Cytokine-Induced Apoptosis DHC Chou, EB Holson, FF Wagner, AJ Tang, RL Maglathlin, TA Lewis, ... Chemistry & Biology 19 (6), 669-673, 2012 | 110 | 2012 |
| A minimized human insulin-receptor-binding motif revealed in a Conus geographus venom insulin JG Menting, J Gajewiak, CA MacRaild, DHC Chou, MM Disotuar, ... Nature structural & molecular biology 23 (10), 916-920, 2016 | 95 | 2016 |
| Fish-hunting cone snail venoms are a rich source of minimized ligands of the vertebrate insulin receptor P Ahorukomeye, MM Disotuar, J Gajewiak, S Karanth, M Watkins, ... Elife 8, e41574, 2019 | 63 | 2019 |
| Application of Thiol–yne/Thiol–ene Reactions for Peptide and Protein Macrocyclizations Y Wang, BJ Bruno, S Cornillie, JM Nogieira, D Chen, TE Cheatham III, ... Chemistry–A European Journal 23 (29), 7087-7092, 2017 | 59 | 2017 |
| A structurally minimized yet fully active insulin based on cone-snail venom insulin principles X Xiong, JG Menting, MM Disotuar, NA Smith, CA Delaine, G Ghabash, ... Nature structural & molecular biology 27 (7), 615-624, 2020 | 52 | 2020 |
| Small-Molecule Suppressors of Cytokine-Induced β-Cell Apoptosis DHC Chou, NE Bodycombe, HA Carrinski, TA Lewis, PA Clemons, ... ACS chemical biology 5 (8), 729-734, 2010 | 51 | 2010 |
| Synthesis of a novel suppressor of β-cell apoptosis via diversity-oriented synthesis DHC Chou, JR Duvall, B Gerard, H Liu, BA Pandya, BC Suh, EM Forbeck, ... ACS medicinal chemistry letters 2 (9), 698-702, 2011 | 50 | 2011 |
| Kinase-independent small-molecule inhibition of JAK-STAT signaling DHC Chou, A Vetere, A Choudhary, SS Scully, M Schenone, A Tang, ... Journal of the American Chemical Society 137 (24), 7929-7934, 2015 | 40 | 2015 |
| The immunoproteasome is induced by cytokines and regulates apoptosis in human islets M Lundh, M Bugliani, T Dahlby, DHC Chou, B Wagner, SM Ghiasi, ... The Journal of endocrinology 233 (3), 369, 2017 | 39 | 2017 |
| Symmetric and asymmetric receptor conformation continuum induced by a new insulin X Xiong, A Blakely, JH Kim, JG Menting, IB Schäfer, HL Schubert, ... Nature Chemical Biology 18 (5), 511-519, 2022 | 26 | 2022 |
| Novel four-disulfide insulin analog with high aggregation stability and potency X Xiong, A Blakely, P Karra, MA VandenBerg, G Ghabash, F Whitby, ... Chemical Science 11 (1), 195-200, 2020 | 26 | 2020 |
| Compounds and methods for treating autoimmune diseases B Wagner, J Duvall, DHC Chou US Patent 8,741,905, 2014 | 23 | 2014 |
| Synthesis of hydrophobic insulin-based peptides using a helping hand strategy MM Disotuar, ME Petersen, JM Nogueira, MS Kay, DHC Chou Organic & biomolecular chemistry 17 (7), 1703-1708, 2019 | 22 | 2019 |
| Discovery of methylene thioacetal-incorporated α-RgIA analogues as potent and stable antagonists of the human α9α10 nicotinic acetylcholine receptor for the treatment of … N Zheng, SB Christensen, C Dowell, L Purushottam, JJ Skalicky, ... Journal of medicinal chemistry 64 (13), 9513-9524, 2021 | 20 | 2021 |
| Synthesis and characterization of an A6-A11 methylene thioacetal human insulin analogue with enhanced stability N Zheng, P Karra, MA VandenBerg, JH Kim, MJ Webber, WL Holland, ... Journal of Medicinal Chemistry 62 (24), 11437-11443, 2019 | 20 | 2019 |
| Display of Single-Chain Insulin-like Peptides on a Yeast Surface MY Jeong, J Rutter, DHC Chou Biochemistry 58 (3), 182-188, 2018 | 19 | 2018 |
