Общедоступные статьи - Paavo HonkakoskiПодробнее...
3 статьи недоступны нигде
Two dietary polyphenols, fisetin and luteolin, reduce inflammation but augment DNA damage-induced toxicity in human RPE cells
M Hytti, D Szabó, N Piippo, E Korhonen, P Honkakoski, K Kaarniranta, ...
The Journal of Nutritional Biochemistry 42, 37-42, 2017
Финансирование: Academy of Finland
Ocular drug-metabolizing enzymes: focus on esterases
A Hammid, P Honkakoski
Drug Metabolism Reviews 56 (3), 175-189, 2024
Финансирование: European Commission
Mechanism‐Based Experimental Models for the Evaluation of BSEP Inhibition and DILI
WA Murphy, C Saran, P Honkakoski, KLR Brouwer
Transporters and Drug‐Metabolizing Enzymes in Drug Toxicity, 261-306, 2021
Финансирование: US National Institutes of Health
33 статьи доступны в некоторых источниках
Towards personalized medicine with a three-dimensional micro-scale perfusion-based two-chamber tissue model system
L Ma, J Barker, C Zhou, W Li, J Zhang, B Lin, G Foltz, J Küblbeck, ...
Biomaterials 33 (17), 4353-4361, 2012
Финансирование: US National Institutes of Health
Fisetin and luteolin protect human retinal pigment epithelial cells from oxidative stress-induced cell death and regulate inflammation
M Hytti, N Piippo, E Korhonen, P Honkakoski, K Kaarniranta, A Kauppinen
Scientific reports 5 (1), 17645, 2015
Финансирование: Academy of Finland
Effluxing ABC transporters in human corneal epithelium
KS Vellonen, E Mannermaa, H Turner, M Häkli, JM Wolosin, T Tervo, ...
Journal of pharmaceutical sciences 99 (2), 1087-1098, 2010
Финансирование: US National Institutes of Health
Quercetin alleviates 4-hydroxynonenal-induced cytotoxicity and inflammation in ARPE-19 cells
M Hytti, N Piippo, A Salminen, P Honkakoski, K Kaarniranta, A Kauppinen
Experimental eye research 132, 208-215, 2015
Финансирование: Academy of Finland
DHCR24 exerts neuroprotection upon inflammation-induced neuronal death
H Martiskainen, KMA Paldanius, T Natunen, M Takalo, M Marttinen, ...
Journal of neuroinflammation 14, 1-16, 2017
Финансирование: Academy of Finland
Deficient neurotransmitter systems and synaptic function in frontotemporal lobar degeneration—Insights into disease mechanisms and current therapeutic approaches
N Huber, S Korhonen, D Hoffmann, S Leskelä, H Rostalski, AM Remes, ...
Molecular psychiatry 27 (3), 1300-1309, 2022
Финансирование: Academy of Finland, European Commission
Metabolism-disrupting chemicals and the constitutive androstane receptor CAR
J Küblbeck, J Niskanen, P Honkakoski
Cells 9 (10), 2306, 2020
Финансирование: European Commission
The EDCMET project: Metabolic effects of endocrine disruptors
J Küblbeck, T Vuorio, J Niskanen, V Fortino, A Braeuning, K Abass, ...
International journal of molecular sciences 21 (8), 3021, 2020
Финансирование: European Commission
Regulation of human pluripotent stem cell-derived hepatic cell phenotype by three-dimensional hydrogel models
S Toivonen, MM Malinen, J Küblbeck, A Petsalo, A Urtti, P Honkakoski, ...
Tissue Engineering Part A 22 (13-14), 971-984, 2016
Финансирование: Finnish Funding Agency for Innovation
Inhibition of BET bromodomains alleviates inflammation in human RPE cells
M Hytti, P Tokarz, E Määttä, N Piippo, E Korhonen, T Suuronen, ...
Biochemical pharmacology 110, 71-79, 2016
Финансирование: Academy of Finland
Ocular metabolism and distribution of drugs in the rabbit eye: Quantitative assessment after intracameral and intravitreal administrations
EM Del Amo, A Hammid, M Tausch, E Toropainen, A Sadeghi, A Valtari, ...
International Journal of Pharmaceutics 613, 121361, 2022
Финансирование: European Commission
Novel bile acid-dependent mechanisms of hepatotoxicity associated with tyrosine kinase inhibitors
C Saran, L Sundqvist, H Ho, J Niskanen, P Honkakoski, KLR Brouwer
The Journal of Pharmacology and Experimental Therapeutics 380 (2), 114-125, 2022
Финансирование: US National Institutes of Health, Academy of Finland
Carboxylesterase activities and protein expression in rabbit and pig ocular tissues
A Hammid, JK Fallon, T Lassila, G Salluce, PC Smith, A Tolonen, A Sauer, ...
Molecular Pharmaceutics 18 (3), 1305-1316, 2021
Финансирование: US National Institutes of Health, European Commission
Protein expression and function of organic anion transporters in short-term and long-term cultures of Huh7 human hepatoma cells
MM Malinen, K Ito, HE Kang, P Honkakoski, KLR Brouwer
European Journal of Pharmaceutical Sciences 130, 186-195, 2019
Финансирование: US National Institutes of Health
Novel in vitro method reveals drugs that inhibit organic solute transporter alpha/beta (OSTα/β)
MM Malinen, A Kauttonen, JJ Beaudoin, N Sjöstedt, P Honkakoski, ...
Molecular pharmaceutics 16 (1), 238-246, 2018
Финансирование: US National Institutes of Health
Functional impact of cytochrome P450 3A (CYP3A) missense variants in cattle
M Giantin, M Rahnasto-Rilla, R Tolosi, L Lucatello, M Pauletto, G Guerra, ...
Scientific Reports 9 (1), 19672, 2019
Финансирование: Government of Italy
Structural features affecting the interactions and transportability of LAT1-targeted phenylalanine drug conjugates
K Bahrami, J Jarvinen, T Laitinen, M Reinisalo, P Honkakoski, A Poso, ...
Molecular Pharmaceutics 20 (1), 206-218, 2022
Финансирование: Academy of Finland
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