Whole-genome and epigenomic landscapes of etiologically distinct subtypes of cholangiocarcinoma A Jusakul, I Cutcutache, CH Yong, JQ Lim, MN Huang, N Padmanabhan, ... Cancer discovery 7 (10), 1116-1135, 2017 | 848 | 2017 |
Aristolochic acids and their derivatives are widely implicated in liver cancers in Taiwan and throughout Asia AWT Ng, SL Poon, MN Huang, JQ Lim, A Boot, W Yu, Y Suzuki, ... Science Translational Medicine 9 (412), 2017 | 377 | 2017 |
Oncogenic activation of the STAT3 pathway drives PD-L1 expression in natural killer/T-cell lymphoma TL Song, ML Nairismägi, Y Laurensia, JQ Lim, J Tan, ZM Li, WL Pang, ... Blood, the Journal of the American Society of Hematology 132 (11), 1146-1158, 2018 | 323 | 2018 |
Loss of tumor suppressor KDM6A amplifies PRC2-regulated transcriptional repression in bladder cancer and can be targeted through inhibition of EZH2 LD Ler, S Ghosh, X Chai, AA Thike, HL Heng, EY Siew, S Dey, LK Koh, ... Science translational medicine 9 (378), eaai8312, 2017 | 220 | 2017 |
Genomic landscapes of breast fibroepithelial tumors J Tan, CK Ong, WK Lim, CCY Ng, AA Thike, LM Ng, V Rajasegaran, ... Nature genetics 47 (11), 1341-1345, 2015 | 218 | 2015 |
In-depth characterization of the cisplatin mutational signature in human cell lines and in esophageal and liver tumors A Boot, MN Huang, AWT Ng, SC Ho, JQ Lim, Y Kawakami, K Chayama, ... Genome research 28 (5), 654-665, 2018 | 161 | 2018 |
JAK-STAT and G-protein-coupled receptor signaling pathways are frequently altered in epitheliotropic intestinal T-cell lymphoma ML Nairismägi, J Tan, JQ Lim, S Nagarajan, CCY Ng, V Rajasegaran, ... Leukemia 30 (6), 1311-1319, 2016 | 157 | 2016 |
Genomic and transcriptomic landscapes of Epstein-Barr virus in extranodal natural killer T-cell lymphoma RJ Peng, BW Han, QQ Cai, XY Zuo, T Xia, JR Chen, LN Feng, JQ Lim, ... Leukemia 33 (6), 1451-1462, 2019 | 119 | 2019 |
Avelumab for the treatment of relapsed or refractory extranodal NK/T-cell lymphoma: an open-label phase 2 study SJ Kim, JQ Lim, Y Laurensia, J Cho, SE Yoon, JY Lee, KJ Ryu, YH Ko, ... Blood, 2020 | 111 | 2020 |
Development of a Comprehensive Sequencing Assay for Inherited Cardiac Condition Genes CJ Pua, J Bhalshankar, K Miao, R Walsh, S John, SQ Lim, K Chow, ... Journal of Cardiovascular Translational Research 9 (1), 3-11, 2016 | 104 | 2016 |
Multiomic analysis and immunoprofiling reveal distinct subtypes of human angiosarcoma JY Chan, JQ Lim, J Yeong, V Ravi, P Guan, A Boot, TKY Tay, ... The Journal of clinical investigation 130 (11), 5833-5846, 2020 | 86 | 2020 |
Whole-genome sequencing identifies responders to Pembrolizumab in relapse/refractory natural-killer/T cell lymphoma JQ Lim, D Huang, T Tang, D Tan, Y Laurensia, RJ Peng, EKY Wong, ... Leukemia 34 (12), 3413-3419, 2020 | 74 | 2020 |
An integrated package for bisulfite DNA methylation data analysis with Indel-sensitive mapping Q Zhou, JQ Lim, WK Sung, G Li BMC bioinformatics 20, 1-11, 2019 | 72 | 2019 |
Beyond fitness tracking: the use of consumer-grade wearable data from normal volunteers in cardiovascular and lipidomics research WK Lim, S Davila, JX Teo, C Yang, CJ Pua, C Blöcker, JQ Lim, J Ching, ... PLoS biology 16 (2), e2004285, 2018 | 72 | 2018 |
Clear cell sarcomas of kidney are characterized by BCOR gene abnormalities including exon 15 internal tandem duplications and BCOR‐CCNB3 gene fusion MK Wong, CCY Ng, CH Kuick, SJ Aw, V Rajasegaran, JQ Lim, ... Histopathology, 2017 | 72 | 2017 |
Genetic risk of extranodal natural killer T-cell lymphoma: a genome-wide association study in multiple populations GW Lin, C Xu, K Chen, HQ Huang, J Chen, B Song, JKC Chan, W Li, ... The Lancet Oncology 21 (2), 306-316, 2020 | 68 | 2020 |
Oncogenic activation of JAK3-STAT signaling confers clinical sensitivity to PRN371, a novel selective and potent JAK3 inhibitor, in natural killer/T-cell lymphoma ML Nairismägi, ME Gerritsen, ZM Li, GC Wijaya, BKH Chia, Y Laurensia, ... Leukemia 32 (5), 1147-1156, 2018 | 68 | 2018 |
BatMeth: improved mapper for bisulfite sequencing reads on DNA methylation JQ Lim, C Tennakoon, G Li, E Wong, Y Ruan, CL Wei, WK Sung Genome Biology 13 (10), R82, 2012 | 68 | 2012 |
Lack of targetable FGFR2 fusions in endemic fluke-associated cholangiocarcinoma S Kongpetch, A Jusakul, JQ Lim, CCY Ng, JY Chan, V Rajasegaran, ... JCO global oncology 6, 628-638, 2020 | 55 | 2020 |
Integrated paired-end enhancer profiling and whole-genome sequencing reveals recurrent CCNE1 and IGF2 enhancer hijacking in primary gastric adenocarcinoma WF Ooi, AM Nargund, KJ Lim, S Zhang, M Xing, A Mandoli, JQ Lim, ... Gut 69 (6), 1039-1052, 2020 | 52 | 2020 |