| Current and future roles of artificial intelligence in medicinal chemistry synthesis TJ Struble, JC Alvarez, SP Brown, M Chytil, J Cisar, RL DesJarlais, ... Journal of medicinal chemistry 63 (16), 8667-8682, 2020 | 211 | 2020 |
| Functional self-assembling bolaamphiphilic polydiacetylenes as colorimetric sensor scaffolds J Song, JS Cisar, CR Bertozzi Journal of the American Chemical Society 126 (27), 8459-8465, 2004 | 138 | 2004 |
| Identification of ABX-1431, a selective inhibitor of monoacylglycerol lipase and clinical candidate for treatment of neurological disorders JS Cisar, OD Weber, JR Clapper, JL Blankman, CL Henry, GM Simon, ... Journal of medicinal chemistry 61 (20), 9062-9084, 2018 | 136 | 2018 |
| Simultaneous structure–activity studies and arming of natural products by C–H amination reveal cellular targets of eupalmerin acetate J Li, JS Cisar, CY Zhou, B Vera, H Williams, AD Rodríguez, BF Cravatt, ... Nature chemistry 5 (6), 510-517, 2013 | 123 | 2013 |
| Fully functionalized small-molecule probes for integrated phenotypic screening and target identification JS Cisar, BF Cravatt Journal of the American chemical society 134 (25), 10385-10388, 2012 | 117 | 2012 |
| Designed semisynthetic protein inhibitors of Ub/Ubl E1 activating enzymes X Lu, SK Olsen, AD Capili, JS Cisar, CD Lima, DS Tan Journal of the American Chemical Society 132 (6), 1748-1749, 2010 | 92 | 2010 |
| Metabolomics annotates ABHD3 as a physiologic regulator of medium-chain phospholipids JZ Long, JS Cisar, D Milliken, S Niessen, C Wang, SA Trauger, G Siuzdak, ... Nature Chemical Biology, 2011 | 75 | 2011 |
| Pharmacokinetic and In Vivo Efficacy Studies of the Mycobactin Biosynthesis Inhibitor Salicyl-AMS in Mice S Lun, H Guo, J Adamson, JS Cisar, TD Davis, SS Chavadi, JD Warren, ... Antimicrobial agents and chemotherapy 57 (10), 5138-5140, 2013 | 65 | 2013 |
| Exploiting ligand conformation in selective inhibition of non-ribosomal peptide synthetase amino acid adenylation with designed macrocyclic small molecules JS Cisar, JA Ferreras, RK Soni, LEN Quadri, DS Tan Journal of the American Chemical Society 129 (25), 7752-7753, 2007 | 56 | 2007 |
| Carbamate compounds and of making and using same JS Cisar, CA Grice, TK Jones, MJ Niphakis, JW Chang, KM Lum, ... US Patent 9,133,148, 2015 | 44 | 2015 |
| Carbamate compounds and of making and using same JS Cisar, CA Grice, TK Jones, MJ Niphakis, JW Chang, KM Lum, ... US Patent 9,487,495, 2016 | 39 | 2016 |
| Monoacylglycerol lipase inhibition in human and rodent systems supports clinical evaluation of endocannabinoid modulators JR Clapper, CL Henry, MJ Niphakis, AM Knize, AR Coppola, GM Simon, ... Journal of Pharmacology and Experimental Therapeutics 367 (3), 494-508, 2018 | 34 | 2018 |
| Small molecule inhibition of microbial natural product biosynthesis—an emerging antibiotic strategy JS Cisar, DS Tan Chemical Society Reviews 37 (7), 1320-1329, 2008 | 29 | 2008 |
| Pyrrolo-pyrrole carbamate and related organic compounds, pharmaceutical compositions, and medical uses thereof TK Jones, JS Cisar, CA Grice, DH Wang, OD Weber US Patent 9,828,379, 2017 | 24 | 2017 |
| Piperazine carbamates and methods of making and using same JS Cisar, CA Grice, TK Jones, OD Weber, DH Wang US Patent 9,771,341, 2017 | 21 | 2017 |
| Activity-based labeling of matrix metalloproteinases in living vertebrate embryos JY Keow, ED Pond, JS Cisar, BF Cravatt, BD Crawford Public Library of Science 7 (8), e43434, 2012 | 19 | 2012 |
| Pyrazole compounds and methods of making and using same CA Grice, TK Jones, KK Duncan, JS Cisar, JE Merit, OD Weber US Patent 10,323,038, 2019 | 17 | 2019 |
| Pyrazole compounds and methods of making and using same CA Grice, TK Jones, KK Duncan, OD Weber, JS Cisar, JE Merit US Patent 10,385,057, 2019 | 16 | 2019 |
| Carbamate compounds and methods of making and using same JS Cisar, CA Grice, TK Jones, MJ Niphakis, JW Chang, KM Lum, ... US Patent 9,957,242, 2018 | 15 | 2018 |
| N-Heterocyclic 3-Pyridyl Carboxamide Inhibitors of DHODH for the Treatment of Acute Myelogenous Leukemia JS Cisar, C Pietsch, LG DeRatt, E Jacoby, F Kazmi, C Keohane, ... Journal of Medicinal Chemistry 65 (16), 11241-11256, 2022 | 11 | 2022 |
