Biomaterials for intervertebral disc regeneration and repair RD Bowles, LA Setton Biomaterials 129, 54-67, 2017 | 363 | 2017 |
Tissue-engineered intervertebral discs produce new matrix, maintain disc height, and restore biomechanical function to the rodent spine RD Bowles, HH Gebhard, R Härtl, LJ Bonassar Proceedings of the National Academy of Sciences 108 (32), 13106-13111, 2011 | 229 | 2011 |
Self-assembly of aligned tissue-engineered annulus fibrosus and intervertebral disc composite via collagen gel contraction RD Bowles, RM Williams, WR Zipfel, LJ Bonassar Tissue Engineering Part A 16 (4), 1339-1348, 2010 | 212 | 2010 |
Injectable laminin-functionalized hydrogel for nucleus pulposus regeneration AT Francisco, RJ Mancino, RD Bowles, JM Brunger, DM Tainter, YT Chen, ... Biomaterials 34 (30), 7381-7388, 2013 | 139 | 2013 |
CRISPR-based epigenome editing of cytokine receptors for the promotion of cell survival and tissue deposition in inflammatory environments N Farhang, JM Brunger, JD Stover, PI Thakore, B Lawrence, F Guilak, ... Tissue Engineering Part A 23 (15-16), 738-749, 2017 | 98 | 2017 |
The circular RNA circSKA3 binds integrin β1 to induce invadopodium formation enhancing breast cancer invasion WW Du, W Yang, X Li, L Fang, N Wu, F Li, Y Chen, Q He, E Liu, Z Yang, ... Molecular therapy 28 (5), 1287-1298, 2020 | 89 | 2020 |
In vivo luminescence imaging of NF‐κB activity and serum cytokine levels predict pain sensitivities in a rodent model of osteoarthritis RD Bowles, BA Mata, RD Bell, TK Mwangi, JL Huebner, VB Kraus, ... Arthritis & rheumatology 66 (3), 637-646, 2014 | 74 | 2014 |
Fabrication of dense anisotropic collagen scaffolds using biaxial compression JL Zitnay, SP Reese, G Tran, N Farhang, RD Bowles, JA Weiss Acta biomaterialia 65, 76-87, 2018 | 69 | 2018 |
Synthesis and characterization of silk fibroin microparticles for intra-articular drug delivery TK Mwangi, RD Bowles, DM Tainter, RD Bell, DL Kaplan, LA Setton International journal of pharmaceutics 485 (1-2), 7-14, 2015 | 67 | 2015 |
Lentiviral CRISPR epigenome editing of inflammatory receptors as a gene therapy strategy for disc degeneration N Farhang, M Ginley-Hidinger, KC Berrett, J Gertz, B Lawrence, ... Human Gene Therapy 30 (9), 1161-1175, 2019 | 63 | 2019 |
Image‐based tissue engineering of a total intervertebral disc implant for restoration of function to the rat lumbar spine RD Bowles, HH Gebhard, JP Dyke, DJ Ballon, A Tomasino, ... NMR in Biomedicine 25 (3), 443-451, 2012 | 61 | 2012 |
CRISPR epigenome editing of AKAP150 in DRG neurons abolishes degenerative IVD-induced neuronal activation JD Stover, N Farhang, KC Berrett, J Gertz, B Lawrence, RD Bowles Molecular Therapy 25 (9), 2014-2027, 2017 | 46 | 2017 |
Total disc replacement using a tissue-engineered intervertebral disc in vivo: new animal model and initial results H Gebhard, R Bowles, J Dyke, T Saleh, S Doty, L Bonassar, R Härtl Evidence-based spine-care journal 1 (02), 62-66, 2010 | 37 | 2010 |
The potential of CRISPR/Cas9 genome editing for the study and treatment of intervertebral disc pathologies O Krupkova, E Cambria, L Besse, A Besse, R Bowles, K Wuertz‐Kozak JOR spine 1 (1), e1003, 2018 | 36 | 2018 |
Synergistic CRISPRa-regulated chondrogenic extracellular matrix deposition without exogenous growth factors N Farhang, B Davis, J Weston, M Ginley-Hidinger, J Gertz, RD Bowles Tissue Engineering Part A 26 (21-22), 1169-1179, 2020 | 27 | 2020 |
Tissue-engineered intervertebral discs: MRI results and histology in the rodent spine: Presented at the 2013 Spine Section Meeting P Grunert, HH Gebhard, RD Bowles, AR James, HG Potter, M Macielak, ... Journal of Neurosurgery: Spine 20 (4), 443-451, 2014 | 26 | 2014 |
Multiplex epigenome editing of dorsal root ganglion neuron receptors abolishes redundant interleukin 6, tumor necrosis factor alpha, and interleukin 1β signaling by the … JD Stover, N Farhang, B Lawrence, RD Bowles Human Gene Therapy 30 (9), 1147-1160, 2019 | 20 | 2019 |
Degenerative IVD conditioned media and acidic pH sensitize sensory neurons to cyclic tensile strain JD Stover, B Lawrence, RD Bowles Journal of Orthopaedic Research® 39 (6), 1192-1203, 2021 | 16 | 2021 |
Novel model-based inquiry of ionic bonding in alginate hydrogels used in tissue engineering for high school students RD Bowles, JM Saroka, SD Archer, LJ Bonassar Journal of Chemical Education 89 (10), 1308-1311, 2012 | 15 | 2012 |
Composite tissue-engineered intervertebral disc with self-assembled annular alignment LJ Bonassar, R Hartl, RD Bowles, HH Gebhard US Patent 9,044,335, 2015 | 14 | 2015 |