| Allosteric integrase inhibitor potency is determined through the inhibition of HIV-1 particle maturation KA Jurado, H Wang, A Slaughter, L Feng, JJ Kessl, Y Koh, W Wang, ... Proceedings of the National Academy of Sciences 110 (21), 8690-8695, 2013 | 239 | 2013 |
| Multimode, cooperative mechanism of action of allosteric HIV-1 integrase inhibitors JJ Kessl, N Jena, Y Koh, H Taskent-Sezgin, A Slaughter, L Feng, ... Journal of Biological Chemistry 287 (20), 16801-16811, 2012 | 216 | 2012 |
| BET proteins promote efficient murine leukemia virus integration at transcription start sites A Sharma, RC Larue, MR Plumb, N Malani, F Male, A Slaughter, JJ Kessl, ... Proceedings of the National Academy of Sciences 110 (29), 12036-12041, 2013 | 213 | 2013 |
| HIV-1 integrase binds the viral RNA genome and is essential during virion morphogenesis JJ Kessl, SB Kutluay, D Townsend, S Rebensburg, A Slaughter, RC Larue, ... Cell 166 (5), 1257-1268. e12, 2016 | 160 | 2016 |
| A new class of multimerization selective inhibitors of HIV-1 integrase A Sharma, A Slaughter, N Jena, L Feng, JJ Kessl, HJ Fadel, N Malani, ... PLoS pathogens 10 (5), e1004171, 2014 | 143 | 2014 |
| The A128T resistance mutation reveals aberrant protein multimerization as the primary mechanism of action of allosteric HIV-1 integrase inhibitors L Feng, A Sharma, A Slaughter, N Jena, Y Koh, N Shkriabai, RC Larue, ... Journal of Biological Chemistry 288 (22), 15813-15820, 2013 | 111 | 2013 |
| The mechanism of H171T resistance reveals the importance of Nδ-protonated His171 for the binding of allosteric inhibitor BI-D to HIV-1 integrase A Slaughter, KA Jurado, N Deng, L Feng, JJ Kessl, N Shkriabai, RC Larue, ... Retrovirology 11, 1-14, 2014 | 51 | 2014 |
| The competitive interplay between allosteric HIV-1 integrase inhibitor BI/D and LEDGF/p75 during the early stage of HIV-1 replication adversely affects inhibitor potency L Feng, V Dharmarajan, E Serrao, A Hoyte, RC Larue, A Slaughter, ... ACS chemical biology 11 (5), 1313-1321, 2016 | 45 | 2016 |
| HIV-1 integrase multimerization as a therapeutic target L Feng, RC Larue, A Slaughter, JJ Kessl, M Kvaratskhelia The Future of HIV-1 Therapeutics: Resistance Is Futile?, 93-119, 2015 | 44 | 2015 |
| A critical role of the C-terminal segment for allosteric inhibitor-induced aberrant multimerization of HIV-1 integrase N Shkriabai, V Dharmarajan, A Slaughter, JJ Kessl, RC Larue, L Feng, ... Journal of Biological Chemistry 289 (38), 26430-26440, 2014 | 43 | 2014 |
| Mechanism of action of allosteric HIV-1 integrase inhibitors AP Slaughter The Ohio State University, 2015 | | 2015 |
| JBC Papers in Press. Published on April 24, 2013 as Manuscript M112. 443390 L Feng, A Sharma, A Slaughter, N Jena, Y Koh, N Shkriabai, RC Larue, ... | | 2013 |
| Multimerization as the Primary Mechanism of Action of Allosteric HIV-1 Integrase Inhibitors L Feng, A Sharma, A Slaughter, N Jena, Y Koh, N Shkriabai, RC Larue, ... J. Antimicrob. Chemother 54, 6-9, 0 | | |
| 834 Ballandras-Colas A, Patel PA, Fuchs JR, Kvaratskhelia M, Engelman A. 835 2013. Allosteric integrase inhibitor potency is determined through the inhibition of 836 HIV-1 … KA Jurado, H Wang, A Slaughter, L Feng, JJ Kessl, Y Koh, W Wang Proc Natl Acad Sci USA 110, 8690-8695, 0 | | |
