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Constanze Depp
Constanze Depp
Broad Institute of MIT and Harvard; Boston Children's Hospital/Harvard Medical School
Подтвержден адрес электронной почты в домене broadinstitute.org
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Процитировано
Процитировано
Год
Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis
SA Berghoff, L Spieth, T Sun, L Hosang, L Schlaphoff, C Depp, T Düking, ...
Nature neuroscience 24 (1), 47-60, 2021
2202021
Myelin dysfunction drives amyloid-β deposition in models of Alzheimer’s disease
C Depp, T Sun, AO Sasmita, L Spieth, SA Berghoff, T Nazarenko, ...
Nature 618 (7964), 349-357, 2023
2162023
Mitochondrial dysfunction and increased glycolysis in prodromal and early Parkinson's blood cells
AM Smith, C Depp, BJ Ryan, GI Johnston, J Alegre‐Abarrategui, S Evetts, ...
Movement Disorders 33 (10), 1580-1590, 2018
1052018
An emerging role of dysfunctional axon-oligodendrocyte coupling in neurodegenerative diseases
AI Mot, C Depp, KA Nave
Dialogues in Clinical Neuroscience 20 (4), 283-292, 2018
582018
Hippocampal neurons respond to brain activity with functional hypoxia
UJ Butt, AA Steixner-Kumar, C Depp, T Sun, I Hassouna, L Wüstefeld, ...
Molecular psychiatry 26 (6), 1790-1807, 2021
462021
Neuronal cholesterol synthesis is essential for repair of chronically demyelinated lesions in mice
SA Berghoff, L Spieth, T Sun, L Hosang, C Depp, AO Sasmita, ...
Cell Reports 37 (4), 2021
432021
Synaptic activity protects neurons against calcium-mediated oxidation and contraction of mitochondria during excitotoxicity
C Depp, C Bas-Orth, L Schroeder, A Hellwig, H Bading
Antioxidants & redox signaling 29 (12), 1109-1124, 2018
392018
Oligodendrocytes produce amyloid-β and contribute to plaque formation alongside neurons in Alzheimer’s disease model mice
AO Sasmita, C Depp, T Nazarenko, T Sun, SB Siems, EC Ong, YB Nkeh, ...
Nature neuroscience 27 (9), 1668-1674, 2024
192024
Apolipoprotein E aggregation in microglia initiates Alzheimer’s disease pathology by seeding β-amyloidosis
S Kaji, SA Berghoff, L Spieth, L Schlaphoff, AO Sasmita, S Vitale, ...
Immunity 57 (11), 2651-2668. e12, 2024
152024
Downregulated expression of lactate dehydrogenase in adult oligodendrocytes and its implication for the transfer of glycolysis products to axons
E Späte, B Zhou, T Sun, K Kusch, E Asadollahi, SB Siems, C Depp, ...
Glia 72 (8), 1374-1391, 2024
92024
Myelin damage links brain ageing to amyloid-β deposition
H Wood
Nature Reviews Neurology 19 (8), 457-457, 2023
72023
Isolated catatonia-like executive dysfunction in mice with forebrain-specific loss of myelin integrity
S Arinrad, C Depp, SB Siems, AO Sasmita, MA Eichel, A Ronnenberg, ...
Elife 12, e70792, 2023
62023
CaMKIIα expressing neurons to report activity-related endogenous hypoxia upon motor-cognitive challenge
UJ Butt, I Hassouna, L Fernandez Garcia-Agudo, AA Steixner-Kumar, ...
International Journal of Molecular Sciences 22 (6), 3164, 2021
52021
Oligodendrocytes and neurons contribute to amyloid-β deposition in Alzheimer’s disease
AO Sasmita, C Depp, T Nazarenko, T Sun, SB Siems, X Yu, C Boehler, ...
bioRxiv, 2023.12. 11.570514, 2023
42023
Axo-vascular coupling mediated by oligodendrocytes
A Restrepo, A Trevisiol, C Restrepo-Arango, C Depp, AO Sasmita, ...
bioRxiv, 2022.06. 16.495900, 2022
42022
A single, open access journal may prevent the primary publishing problems in the life sciences
P Lewis, C Depp
Accountability in Research 26 (6), 391-396, 2019
22019
Ageing-associated myelin dysfunction as a driver of amyloid deposition in Alzheimer’s disease
CM Depp
Dissertation, Göttingen, Georg-August Universität, 2021, 2022
12022
Parental origin of transgene modulates amyloid-β plaque burden in the 5xFAD mouse model of Alzheimer’s disease
AO Sasmita, EC Ong, T Nazarenko, S Mao, L Komarek, M Thalmann, ...
Neuron, 2025
2025
Apolipoprotein E aggregation in microglia initiates Alzheimer’s disease pathology by seeding β-amyloidosis
S Kaji, SA Berghoff, L Spieth, L Schlaphoff, AO Sasmita, S Vitale, ...
Immunity 58 (1), 263, 2025
2025
Myelin dysfunction drives amyloid deposition in mouse models of Alzheimer's disease
C Depp, KA Nave
GLIA 71, E124-E124, 2023
2023
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