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Jurian Schuijers
Jurian Schuijers
Assistant Professor at Center for Molecular Medicine, UMC Utrecht
Подтвержден адрес электронной почты в домене umcutrecht.nl - Главная страница
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Процитировано
Год
Coactivator condensation at super-enhancers links phase separation and gene control
BR Sabari, A Dall’Agnese, A Boija, IA Klein, EL Coffey, K Shrinivas, ...
Science 361 (6400), eaar3958, 2018
22002018
Transcription factors activate genes through the phase-separation capacity of their activation domains
A Boija, IA Klein, BR Sabari, A Dall’Agnese, EL Coffey, AV Zamudio, ...
Cell 175 (7), 1842-1855. e16, 2018
15912018
Control of cell identity genes occurs in insulated neighborhoods in mammalian chromosomes
JM Dowen, ZP Fan, D Hnisz, G Ren, BJ Abraham, LN Zhang, ...
Cell 159 (2), 374-387, 2014
9702014
Unlimited in vitro expansion of adult bi‐potent pancreas progenitors through the Lgr5/R‐spondin axis
M Huch, P Bonfanti, SF Boj, T Sato, CJM Loomans, M Van De Wetering, ...
The EMBO journal 32 (20), 2708-2721, 2013
7612013
Convergence of developmental and oncogenic signaling pathways at transcriptional super-enhancers
D Hnisz, J Schuijers, CY Lin, AS Weintraub, BJ Abraham, TI Lee, ...
Molecular cell 58 (2), 362-370, 2015
5112015
Enhancer features that drive formation of transcriptional condensates
K Shrinivas, BR Sabari, EL Coffey, IA Klein, A Boija, AV Zamudio, ...
Molecular cell 75 (3), 549-561. e7, 2019
3882019
Adult mammalian stem cells: the role of Wnt, Lgr5 and R‐spondins
J Schuijers, H Clevers
The EMBO journal 31 (12), 2685-2696, 2012
3192012
Ascl2 acts as an R-spondin/Wnt-responsive switch to control stemness in intestinal crypts
J Schuijers, JP Junker, M Mokry, P Hatzis, BK Koo, V Sasselli, ...
Cell stem cell 16 (2), 158-170, 2015
3062015
Mediator condensates localize signaling factors to key cell identity genes
AV Zamudio, A Dall’Agnese, JE Henninger, JC Manteiga, LK Afeyan, ...
Molecular cell 76 (5), 753-766. e6, 2019
2432019
Wnt‐induced transcriptional activation is exclusively mediated by TCF/LEF
J Schuijers, M Mokry, P Hatzis, E Cuppen, H Clevers
The EMBO journal 33 (2), 146-156, 2014
2162014
Transcriptional dysregulation of MYC reveals common enhancer-docking mechanism
J Schuijers, JC Manteiga, AS Weintraub, DS Day, AV Zamudio, D Hnisz, ...
Cell reports 23 (2), 349-360, 2018
1962018
MeCP2 links heterochromatin condensates and neurodevelopmental disease
CH Li, EL Coffey, A Dall’Agnese, NM Hannett, X Tang, JE Henninger, ...
Nature 586 (7829), 440-444, 2020
1832020
DNA methylation dynamics during intestinal stem cell differentiation reveals enhancers driving gene expression in the villus
LTJ Kaaij, M van de Wetering, F Fang, B Decato, A Molaro, ...
Genome biology 14, 1-15, 2013
1262013
Robust cre-mediated recombination in small intestinal stem cells utilizing the olfm4 locus
J Schuijers, LG van der Flier, J van Es, H Clevers
Stem cell reports 3 (2), 234-241, 2014
1192014
TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions
MP Verzi, P Hatzis, R Sulahian, J Philips, J Schuijers, H Shin, E Freed, ...
Proceedings of the National Academy of Sciences 107 (34), 15157-15162, 2010
952010
Integrated genome-wide analysis of transcription factor occupancy, RNA polymerase II binding and steady-state RNA levels identify differentially regulated functional gene classes
M Mokry, P Hatzis, J Schuijers, N Lansu, FP Ruzius, H Clevers, E Cuppen
Nucleic acids research 40 (1), 148-158, 2012
862012
Efficient double fragmentation ChIP-seq provides nucleotide resolution protein-DNA binding profiles
M Mokry, P Hatzis, E de Bruijn, J Koster, R Versteeg, J Schuijers, ...
PloS one 5 (11), e15092, 2010
612010
Regulation and dysregulation of chromosome structure in cancer
D Hnisz, J Schuijers, CH Li, RA Young
Annual Review of Cancer Biology 2 (1), 21-40, 2018
412018
Coactivator condensation at super-enhancers links phase separation and gene control. Science
BR Sabari, A Dall’Agnese, A Boija, IA Klein, EL Coffey, K Shrinivas, ...
112018
Targeted perturbation of signaling-driven condensates
T Gui, C Fleming, C Manzato, B Bourgeois, N Sirati, J Heuer, ...
Molecular Cell 83 (22), 4141-4157. e11, 2023
92023
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