| Highly Efficient Syntheses of Azetidines, Pyrrolidines, and Indolines via Palladium Catalyzed Intramolecular Amination of C(sp3)–H and C(sp2)–H Bonds at γ and … G He, Y Zhao, S Zhang, C Lu, G Chen Journal of the American Chemical Society 134 (1), 3-6, 2012 | 527 | 2012 |
| Syntheses and Transformations of α-Amino Acids via Palladium-Catalyzed Auxiliary-Directed sp3 C–H Functionalization G He, B Wang, WA Nack, G Chen Accounts of Chemical Research 49 (4), 635-645, 2016 | 479 | 2016 |
| A Practical Strategy for the Structural Diversification of Aliphatic Scaffolds through the Palladium‐Catalyzed Picolinamide‐Directed Remote Functionalization of Unactivated C … G He, G Chen Angewandte Chemie International Edition 22 (50), 5192-5196, 2011 | 405 | 2011 |
| Palladium-Catalyzed Picolinamide-Directed Alkylation of Unactivated C(sp3)–H Bonds with Alkyl Iodides SY Zhang, G He, WA Nack, Y Zhao, Q Li, G Chen Journal of the American Chemical Society 135 (6), 2124-2127, 2013 | 382 | 2013 |
| Total Synthesis of Celogentin C by Stereoselective C-H Activation Y Feng, G Chen Angewandte Chemie International Edition 49 (5), 958-961, 2010 | 345 | 2010 |
| Stereoselective Synthesis of β-Alkylated α-Amino Acids via Palladium-Catalyzed Alkylation of Unactivated Methylene C(sp3)–H Bonds with Primary Alkyl Halides SY Zhang, Q Li, G He, WA Nack, G Chen Journal of the American Chemical Society 135 (32), 12135-12141, 2013 | 341 | 2013 |
| Efficient Alkyl Ether Synthesis via Palladium-Catalyzed, Picolinamide-Directed Alkoxylation of Unactivated C(sp3)–H and C(sp2)–H Bonds at Remote Positions SY Zhang, G He, Y Zhao, K Wright, WA Nack, G Chen Journal of the American Chemical Society 134 (17), 7313-7316, 2012 | 335 | 2012 |
| Photoredox-mediated Minisci C–H alkylation of N-heteroarenes using boronic acids and hypervalent iodine GX Li, CA Morales-Rivera, Y Wang, F Gao, G He, P Liu, G Chen Chemical science 7 (10), 6407-6412, 2016 | 325 | 2016 |
| Use of a Readily Removable Auxiliary Group for the Synthesis of Pyrrolidones by the Palladium‐Catalyzed Intramolecular Amination of Unactivated γ C(sp3)-H Bonds G He, SY Zhang, WA Nack, Q Li, G Chen Angewandte Chemie International Edition 52 (42), 11124-11128, 2013 | 284 | 2013 |
| Halogen-bond-promoted photoactivation of perfluoroalkyl iodides: A photochemical protocol for perfluoroalkylation reactions Y Wang, J Wang, GX Li, G He, G Chen Organic letters 19 (6), 1442-1445, 2017 | 283 | 2017 |
| A general strategy for synthesis of cyclophane-braced peptide macrocycles via palladium-catalysed intramolecular sp3 C−H arylation X Zhang, G Lu, M Sun, M Mahankali, Y Ma, M Zhang, W Hua, Y Hu, ... Nature chemistry 10 (5), 540-548, 2018 | 207 | 2018 |
| Copper-Catalyzed Carboxamide-Directed Ortho Amination of Anilines with Alkylamines at Room Temperature Q Li, SY Zhang, G He, Z Ai, WA Nack, G Chen Organic letters 16 (6), 1764-1767, 2014 | 207 | 2014 |
| Palladium-Catalyzed Alkylation of ortho-C(sp2)–H Bonds of Benzylamide Substrates with Alkyl Halides Y Zhao, G Chen Organic letters 13 (18), 4850-4853, 2011 | 204 | 2011 |
| A visible-light-promoted radical reaction system for azidation and halogenation of tertiary aliphatic C–H bonds Y Wang, GX Li, G Yang, G He, G Chen Chemical Science 7 (4), 2679-2683, 2016 | 194 | 2016 |
| Building complex glycopeptides: Development of a cysteine-free native chemical ligation protocol. B Wu, J Chen, JD Warren, G Chen, Z Hua, SJ Danishefsky Angewandte Chemie (International ed. in English) 45 (25), 4116-4125, 2006 | 189 | 2006 |
| Improved Protocol for Indoline Synthesis via Palladium-Catalyzed Intramolecular C(sp2)–H Amination G He, C Lu, Y Zhao, WA Nack, G Chen Organic letters 14 (12), 2944-2947, 2012 | 179 | 2012 |
| Anticancer peptidylarginine deiminase (PAD) inhibitors regulate the autophagy flux and the mammalian target of rapamycin complex 1 activity Y Wang, P Li, S Wang, J Hu, XA Chen, J Wu, M Fisher, K Oshaben, ... Journal of Biological Chemistry 287 (31), 25941-25953, 2012 | 176 | 2012 |
| Iridium-Catalyzed Enantioselective C(sp3)–H Amidation Controlled by Attractive Noncovalent Interactions H Wang, Y Park, Z Bai, S Chang, G He, G Chen Journal of the American Chemical Society 141 (17), 7194-7201, 2019 | 175 | 2019 |
| Reactivity of functional groups on the protein surface: development of epoxide probes for protein labeling G Chen, A Heim, D Riether, D Yee, Y Milgrom, MA Gawinowicz, D Sames Journal of the American Chemical Society 125 (27), 8130-8133, 2003 | 173 | 2003 |
| Facile Benzo-Ring Construction via Palladium-Catalyzed Functionalization of Unactivated sp3 C−H Bonds under Mild Reaction Conditions Y Feng, Y Wang, B Landgraf, S Liu, G Chen Organic Letters 12 (15), 3414-3417, 2010 | 171 | 2010 |