Late Stage Benzylic C–H Fluorination with [18F]Fluoride for PET Imaging X Huang, W Liu, H Ren, R Neelamegam, JM Hooker, JT Groves Journal of the American Chemical Society 136 (19), 6842-6845, 2014 | 279 | 2014 |
Autoradiography validation of novel tau PET tracer [F-18]-MK-6240 on human postmortem brain tissue C Aguero, M Dhaynaut, MD Normandin, AC Amaral, NJ Guehl, ... Acta neuropathologica communications 7, 1-15, 2019 | 139 | 2019 |
Brain-penetrant LSD1 inhibitors can block memory consolidation R Neelamegam, EL Ricq, M Malvaez, D Patnaik, S Norton, SM Carlin, ... ACS chemical neuroscience 3 (2), 120-128, 2012 | 138 | 2012 |
Synthesis and Imaging Validation of [18F]MDL100907 Enabled by Ni-Mediated Fluorination H Ren, HY Wey, M Strebl, R Neelamegam, T Ritter, JM Hooker ACS Chemical Neuroscience 5 (7), 611-615, 2014 | 70 | 2014 |
Imaging Evaluation of 5HT2C Agonists, [11C]WAY-163909 and [11C]Vabicaserin, Formed by Pictet–Spengler Cyclization R Neelamegam, T Hellenbrand, FA Schroeder, C Wang, JM Hooker Journal of Medicinal Chemistry 57 (4), 1488-1494, 2014 | 63 | 2014 |
A simple iodination protocol via in situ generated ICl using NaI/FeCl3 AK Mohanakrishnan, C Prakash, N Ramesh Tetrahedron 62 (14), 3242-3247, 2006 | 41 | 2006 |
PET imaging demonstrates histone deacetylase target engagement and clarifies brain penetrance of known and novel small molecule inhibitors in rat FA Schroeder, C Wang, GC Van de Bittner, R Neelamegam, ... ACS chemical neuroscience 5 (10), 1055-1062, 2014 | 40 | 2014 |
Design, synthesis, and evaluation of hydroxamic acid-based molecular probes for in vivo imaging of histone deacetylase (HDAC) in brain C Wang, TE Eessalu, VN Barth, CH Mitch, FF Wagner, Y Hong, ... American journal of nuclear medicine and molecular imaging 4 (1), 29, 2013 | 39 | 2013 |
cGMP production of the radiopharmaceutical [18F] MK‐6240 for PET imaging of human neurofibrillary tangles TL Collier, DL Yokell, E Livni, PA Rice, S Celen, K Serdons, ... Journal of Labelled Compounds and Radiopharmaceuticals 60 (5), 263-269, 2017 | 30 | 2017 |
Development of a fluorinated class-I HDAC radiotracer reveals key chemical determinants of brain penetrance MG Strebl, C Wang, FA Schroeder, MS Placzek, HY Wey, ... ACS chemical neuroscience 7 (5), 528-533, 2016 | 30 | 2016 |
Synthesis of di-, tri-, and tetra-substituted carbazole analogs involving annulation methodology N Ramesh, GG Rajeshwaran, AK Mohanakrishnan Tetrahedron 65 (18), 3592-3602, 2009 | 28 | 2009 |
Radiosynthesis and evaluation of [11C] EMPA as a potential PET tracer for orexin 2 receptors C Wang, CK Moseley, SM Carlin, CM Wilson, R Neelamegam, JM Hooker Bioorganic & medicinal chemistry letters 23 (11), 3389-3392, 2013 | 25 | 2013 |
An Efficient and Practical Radiosynthesis of [11C]Temozolomide CK Moseley, SM Carlin, R Neelamegam, JM Hooker Organic letters 14 (23), 5872-5875, 2012 | 24 | 2012 |
Evaluation of the potassium channel tracer [18F]3F4AP in rhesus macaques NJ Guehl, KM Ramos-Torres, C Linnman, SH Moon, M Dhaynaut, ... Journal of Cerebral Blood Flow & Metabolism 41 (7), 1721-1733, 2021 | 23 | 2021 |
Discrepancies in kappa opioid agonist binding revealed through PET imaging MS Placzek, FA Schroeder, T Che, HY Wey, R Neelamegam, C Wang, ... ACS Chemical Neuroscience 10 (1), 384-395, 2018 | 23 | 2018 |
Synthesis and Evaluation of Methylated Arylazepine Compounds for PET Imaging of 5-HT2c Receptors ML Granda, SM Carlin, CK Moseley, R Neelamegam, JB Mandeville, ... ACS Chemical Neuroscience 4 (2), 261-265, 2013 | 23 | 2013 |
Novel radioligands for imaging sigma-1 receptor in brain using positron emission tomography (PET) Y Lan, P Bai, Z Chen, R Neelamegam, MS Placzek, H Wang, SA Fiedler, ... Acta Pharmaceutica Sinica B 9 (6), 1204-1215, 2019 | 21 | 2019 |
Dimerization of phenols and naphthols using an aqueous sodium hypochlorite R Neelamegam, MT Palatnik, J Fraser-Rini, M Slifstein, A Abi-Dargham, ... Tetrahedron Letters 51 (18), 2497-2499, 2010 | 19 | 2010 |
Ethyl 2-bromomethyl-1-phenylsulfonyl-1H-indole-3-carboxylate G Chakkaravarthi, N Ramesh, AK Mohanakrishnan, V Manivannan Acta Crystallographica Section E: Structure Reports Online 63 (8), o3564-o3564, 2007 | 18 | 2007 |
In vivo imaging of mGlu5 receptor expression in humans with Fragile X Syndrome towards development of a potential biomarker M Mody, Y Petibon, P Han, D Kuruppu, C Ma, D Yokell, R Neelamegam, ... Scientific reports 11 (1), 15897, 2021 | 16 | 2021 |