ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19 JM Leung, CX Yang, A Tam, T Shaipanich, TL Hackett, GK Singhera, ... European Respiratory Journal 55 (5), 2020 | 1003 | 2020 |
Intrinsic phenotypic differences of asthmatic epithelium and its inflammatory responses to respiratory syncytial virus and air pollution TL Hackett, GK Singhera, F Shaheen, P Hayden, GR Jackson, RG Hegele, ... American journal of respiratory cell and molecular biology 45 (5), 1090-1100, 2011 | 259 | 2011 |
Toll-like receptor 4-mediated activation of p38 mitogen-activated protein kinase is a determinant of respiratory virus entry and tropism D Marchant, GK Singhera, S Utokaparch, TL Hackett, JH Boyd, Z Luo, X Si, ... Journal of virology 84 (21), 11359-11373, 2010 | 182 | 2010 |
Secretion of IL-13 by airway epithelial cells enhances epithelial repair via HB-EGF S Allahverdian, N Harada, GK Singhera, DA Knight, DR Dorscheid American journal of respiratory cell and molecular biology 38 (2), 153-160, 2008 | 136 | 2008 |
Insulin-like growth factor-1 protects ischemic murine myocardium from ischemia/reperfusion associated injury EY Davani, Z Brumme, GK Singhera, HCF Côté, PR Harrigan, ... Critical care 7, 1-8, 2003 | 87 | 2003 |
Erythropoietin inhibits respiratory epithelial cell apoptosis in a model of acute lung injury R MacRedmond, GK Singhera, DR Dorscheid European Respiratory Journal 33 (6), 1403-1414, 2009 | 76 | 2009 |
Conjugated linoleic acid improves airway hyper‐reactivity in overweight mild asthmatics R MacRedmond, G Singhera, S Attridge, M Bahzad, C Fava, Y Lai, ... Clinical & Experimental Allergy 40 (7), 1071-1078, 2010 | 70 | 2010 |
IL-13 and TH2 cytokine exposure triggers matrix metalloproteinase 7–mediated Fas ligand cleavage from bronchial epithelial cells SJ Wadsworth, R Atsuta, JO McIntyre, TL Hackett, GK Singhera, ... Journal of Allergy and Clinical Immunology 126 (2), 366-374. e8, 2010 | 61 | 2010 |
Cardiac ICAM-1 mediates leukocyte-dependent decreased ventricular contractility in endotoxemic mice EY Davani, JH Boyd, DR Dorscheid, Y Wang, A Meredith, E Chau, ... Cardiovascular Research 72 (1), 134-142, 2006 | 51 | 2006 |
Fast, cheap and out of control: A zero curation model for ontology development BM Good, EM Tranfield, PC Tan, M Shehata, GK Singhera, J Gosselink, ... Biocomputing 2006, 128-139, 2006 | 51 | 2006 |
Urban particulate matter increases human airway epithelial cell IL-1β secretion following scratch wounding and H1N1 influenza A exposure in vitro JA Hirota, DJ Marchant, GK Singhera, F Moheimani, DR Dorscheid, ... Experimental lung research 41 (6), 353-362, 2015 | 44 | 2015 |
Formation of a stable mimic of ambient particulate matter containing viable infectious respiratory syncytial virus and its dry-deposition directly onto cell cultures TM Cruz-Sanchez, AE Haddrell, TL Hackett, GK Singhera, D Marchant, ... Analytical chemistry 85 (2), 898-906, 2013 | 44 | 2013 |
Increased myofibroblasts in the small airways, and relationship to remodelling and functional changes in smokers and COPD patients: potential role of epithelial–mesenchymal … MS Eapen, W Lu, TL Hackett, GK Singhera, MQ Mahmood, A Hardikar, ... ERJ open research 7 (2), 2021 | 41 | 2021 |
Characterization of COVID-19-associated cardiac injury: evidence for a multifactorial disease in an autopsy cohort PJ Hanson, F Liu-Fei, C Ng, TA Minato, C Lai, AR Hossain, R Chan, ... Laboratory Investigation 102 (8), 814-825, 2022 | 39 | 2022 |
Hedgehog signaling in the airway epithelium of patients with chronic obstructive pulmonary disease A Tam, M Hughes, KM McNagny, M Obeidat, TL Hackett, JM Leung, ... Scientific reports 9 (1), 3353, 2019 | 35 | 2019 |
Interleukin-9 and-13 inhibit spontaneous and corticosteroid induced apoptosis of normal airway epithelial cells GK Singhera, R MacRedmond, DR Dorscheid Experimental lung research 34 (9), 579-598, 2008 | 33 | 2008 |
Dysregulation of endocytic machinery and ACE2 in small airways of smokers and COPD patients can augment their susceptibility to SARS-CoV-2 (COVID-19) infections MS Eapen, W Lu, TL Hackett, GK Singhera, IE Thompson, KD McAlinden, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 320 (1 …, 2021 | 28 | 2021 |
Transcriptomic and proteomic host response to Aspergillus fumigatus conidia in an air-liquid interface model of human bronchial epithelium A Toor, L Culibrk, GK Singhera, KM Moon, A Prudova, LJ Foster, ... PloS one 13 (12), e0209652, 2018 | 28 | 2018 |
Expression of surfactant protein D in airways of asthmatics and interleukin-13 modulation of surfactant protein D in human models of airway epithelium J Xu, GK Singhera, DR Dorscheid Respiratory Research 16, 1-12, 2015 | 28 | 2015 |
Lipid nanoparticle formulations for optimal RNA-based topical delivery to murine airways A Tam, J Kulkarni, K An, L Li, DR Dorscheid, GK Singhera, P Bernatchez, ... European Journal of Pharmaceutical Sciences 176, 106234, 2022 | 25 | 2022 |