NMDAR inhibition-independent antidepressant actions of ketamine metabolites P Zanos, R Moaddel, PJ Morris, P Georgiou, J Fischell, GI Elmer, ... Nature 533 (7604), 481-486, 2016 | 1598 | 2016 |
A high-fat diet and NAD+ activate Sirt1 to rescue premature aging in cockayne syndrome M Scheibye-Knudsen, SJ Mitchell, EF Fang, T Iyama, T Ward, J Wang, ... Cell metabolism 20 (5), 840-855, 2014 | 379 | 2014 |
(R, S)-Ketamine metabolites (R, S)-norketamine and (2S, 6S)-hydroxynorketamine increase the mammalian target of rapamycin function RK Paul, NS Singh, M Khadeer, R Moaddel, M Sanghvi, CE Green, ... The Journal of the American Society of Anesthesiologists 121 (1), 149-159, 2014 | 132 | 2014 |
Screening approach, optimisation and scale-up for chiral liquid chromatography of cathinones RWH Perera, I Abraham, S Gupta, P Kowalska, D Lightsey, C Marathaki, ... Journal of Chromatography A 1269, 189-197, 2012 | 51 | 2012 |
What is hydroxynorketamine and what can it bring to neurotherapeutics? NS Singh, CA Zarate Jr, R Moaddel, M Bernier, IW Wainer Expert review of neurotherapeutics 14 (11), 1239-1242, 2014 | 49 | 2014 |
Synthesis and characterization of a SIRT6 open tubular column: predicting deacetylation activity using frontal chromatography N Singh, S Ravichandran, DD Norton, SD Fugmann, R Moaddel Analytical biochemistry 436 (2), 78-83, 2013 | 42 | 2013 |
Zanos et al. reply P Zanos, R Moaddel, PJ Morris, P Georgiou, J Fischell, GI Elmer, ... Nature 546 (7659), E4-E5, 2017 | 41 | 2017 |
Activation of β2-adrenergic receptor by (R, R′)-4′-methoxy-1-naphthylfenoterol inhibits proliferation and motility of melanoma cells A Wnorowski, M Sadowska, RK Paul, NS Singh, A Boguszewska-Czubara, ... Cellular signalling 27 (5), 997-1007, 2015 | 37 | 2015 |
The identification of a novel SIRT6 modulator from Trigonella foenum-graecum using ligand fishing with protein coated magnetic beads N Singh, S Ravichandran, K Spelman, SD Fugmann, R Moaddel Journal of Chromatography B 968, 105-111, 2014 | 35 | 2014 |
Pharmacophore model of the quercetin binding site of the SIRT6 protein S Ravichandran, N Singh, D Donnelly, M Migliore, P Johnson, C Fishwick, ... Journal of Molecular Graphics and Modelling 49, 38-46, 2014 | 35 | 2014 |
Capillary electrophoresis–laser-induced fluorescence (CE-LIF) assay for measurement of intracellular d-serine and serine racemase activity NS Singh, RK Paul, M Sichler, R Moaddel, M Bernier, IW Wainer Analytical Biochemistry 421 (2), 460-466, 2012 | 35 | 2012 |
Development and validation of a sensitive LC–MS/MS method for the determination of d-serine in human plasma Y Xie, GM Alexander, RJ Schwartzman, N Singh, MC Torjman, ... Journal of pharmaceutical and biomedical analysis 89, 1-5, 2014 | 34 | 2014 |
Ketamine metabolites enantioselectively decrease intracellular D-serine concentrations in PC-12 cells NS Singh, E Rutkowska, A Plazinska, M Khadeer, R Moaddel, K Jozwiak, ... PLoS One 11 (4), e0149499, 2016 | 31 | 2016 |
Selective GPR55 antagonism reduces chemoresistance in cancer cells NS Singh, M Bernier, IW Wainer Pharmacological research 111, 757-766, 2016 | 30 | 2016 |
Nicotinic acetylcholine receptor antagonists alter the function and expression of serine racemase in PC-12 and 1321N1 cells NS Singh, RK Paul, A Ramamoorthy, MC Torjman, R Moaddel, M Bernier, ... Cellular signalling 25 (12), 2634-2645, 2013 | 29 | 2013 |
A molecular model of the enantioselective liquid chromatographic separation of (R, S)-ifosfamide and its N-dechloroethylated metabolites on a teicoplanin aglycon chiral … S Ravichandran, JR Collins, N Singh, IW Wainer Journal of Chromatography A 1269, 218-225, 2012 | 23 | 2012 |
GPR55 receptor antagonist decreases glycolytic activity in PANC‐1 pancreatic cancer cell line and tumor xenografts M Bernier, J Catazaro, NS Singh, A Wnorowski, A Boguszewska‐Czubara, ... International journal of cancer 141 (10), 2131-2142, 2017 | 21 | 2017 |
The synthesis and characterization of a nuclear membrane affinity chromatography column for the study of human breast cancer resistant protein (BCRP) using nuclear membranes … KL Habicht, C Frazier, N Singh, R Shimmo, IW Wainer, R Moaddel Journal of pharmaceutical and biomedical analysis 72, 159-162, 2013 | 20 | 2013 |
Subchronic administration of (R, S)-ketamine induces ketamine ring hydroxylation in Wistar rats R Moaddel, M Sanghvi, A Ramamoorthy, K Jozwiak, N Singh, C Green, ... Journal of pharmaceutical and biomedical analysis 127, 3-8, 2016 | 19 | 2016 |
Multiple protein stationary phases: a review NS Singh, KL Habicht, KSS Dossou, R Shimmo, IW Wainer, R Moaddel Journal of Chromatography B 968, 64-68, 2014 | 17 | 2014 |