Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian–human immunodeficiency virus infection TW Baba, V Liska, R Hofmann-Lehmann, J Vlasak, W Xu, S Ayehunie, ... Nature medicine 6 (2), 200-206, 2000 | 1120 | 2000 |
Contribution of variable domains to the stability of humanized IgG1 monoclonal antibodies RM Ionescu, J Vlasak, C Price, M Kirchmeier Journal of pharmaceutical sciences 97 (4), 1414-1426, 2008 | 372 | 2008 |
Fragmentation of monoclonal antibodies J Vlasak, R Ionescu MAbs 3 (3), 253-263, 2011 | 358 | 2011 |
Heterogeneity of monoclonal antibodies revealed by charge-sensitive methods J Vlasak, R Ionescu Current pharmaceutical biotechnology 9 (6), 468-481, 2008 | 343 | 2008 |
Impact of methionine oxidation in human IgG1 Fc on serum half-life of monoclonal antibodies W Wang, J Vlasak, Y Li, P Pristatsky, Y Fang, T Pittman, J Roman, Y Wang, ... Molecular immunology 48 (6-7), 860-866, 2011 | 288 | 2011 |
Identification and characterization of asparagine deamidation in the light chain CDR1 of a humanized IgG1 antibody J Vlasak, MC Bussat, S Wang, E Wagner-Rousset, M Schaefer, ... Analytical biochemistry 392 (2), 145-154, 2009 | 287 | 2009 |
Impact of methionine oxidation on the binding of human IgG1 to FcRn and Fcγ receptors A Bertolotti-Ciarlet, W Wang, R Lownes, P Pristatsky, Y Fang, T McKelvey, ... Molecular immunology 46 (8-9), 1878-1882, 2009 | 265 | 2009 |
Postnatal passive immunization of neonatal macaques with a triple combination of human monoclonal antibodies against oral simian-human immunodeficiency virus challenge R Hofmann-Lehmann, J Vlasak, RA Rasmussen, BA Smith, TW Baba, ... Journal of virology 75 (16), 7470-7480, 2001 | 204 | 2001 |
β-Elimination and peptide bond hydrolysis: two distinct mechanisms of human IgG1 hinge fragmentation upon storage SL Cohen, C Price, J Vlasak Journal of the American Chemical Society 129 (22), 6976-6977, 2007 | 175 | 2007 |
Live attenuated, nef-deleted SIV is pathogenic in most adult macaques after prolonged observation R Hofmann-Lehmann, J Vlasak, AL Williams, AL Chenine, HM McClure, ... Aids 17 (2), 157-166, 2003 | 156 | 2003 |
Effect of protein structure on deamidation rate in the Fc fragment of an IgG1 monoclonal antibody S Sinha, L Zhang, S Duan, TD Williams, J Vlasak, R Ionescu, EM Topp Protein Science 18 (8), 1573-1584, 2009 | 91 | 2009 |
Evidence for trisulfide bonds in a recombinant variant of a human IgG2 monoclonal antibody P Pristatsky, SL Cohen, D Krantz, J Acevedo, R Ionescu, J Vlasak Analytical chemistry 81 (15), 6148-6155, 2009 | 88 | 2009 |
Neutralization of diverse human cytomegalovirus strains conferred by antibodies targeting viral gH/gL/pUL128-131 pentameric complex S Ha, F Li, MC Troutman, DC Freed, A Tang, JW Loughney, D Wang, ... Journal of virology 91 (7), 10.1128/jvi. 02033-16, 2017 | 76 | 2017 |
Isolation and characterization of IgG1 with asymmetrical Fc glycosylation S Ha, Y Ou, J Vlasak, Y Li, S Wang, K Vo, Y Du, A Mach, Y Fang, N Zhang Glycobiology 21 (8), 1087-1096, 2011 | 72 | 2011 |
Postnatal pre‐and postexposure passive immunization strategies: protection of neonatal macaques against oral simian–human immunodeficiency virus challenge R Hofmann‐Lehmann, J Vlasak, RA Rasmussen, S Jiang, PL Li, TW Baba, ... Journal of medical primatology 31 (3), 109-119, 2002 | 72 | 2002 |
Protection of neonatal macaques against experimental SHIV infection by human neutralizing monoclonal antibodies RM Ruprecht, R Hofmann-Lehmann, BA Smith-Franklin, RA Rasmussen, ... Transfusion clinique et biologique 8 (4), 350-358, 2001 | 67 | 2001 |
Neutralizing antibodies as a potential secondary protective mechanism during chronic SHIV infection in CD8+ T-cell-depleted macaques RA Rasmussen, R Hofmann-Lehmann, PL Li, J Vlasak, JE Schmitz, ... Aids 16 (6), 829-838, 2002 | 59 | 2002 |
Passive immunization against oral AIDS virus transmission: An approach to prevent mother‐to‐infant HIV‐1 transmission? R Hofmann‐Lehmann, RA Rasmussen, J Vlasak, BA Smith, TW Baba, ... Journal of medical primatology 30 (4), 190-196, 2001 | 46 | 2001 |
DNA prime/protein boost vaccine strategy in neonatal macaques against simian human immunodeficiency virus RA Rasmussen, R Hofmann‐Lehmann, DC Montefiori, PL Li, V Liska, ... Journal of medical primatology 31 (1), 40-60, 2002 | 45 | 2002 |
Use of flow cytometry for characterization of human cytomegalovirus vaccine particles J Vlasak, VM Hoang, S Christanti, R Peluso, F Li, TD Culp Vaccine 34 (20), 2321-2328, 2016 | 40 | 2016 |