Общедоступные статьи - Greg M. ThurberПодробнее...
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Pharmacokinetic and immunological considerations for expanding the therapeutic window of next-generation antibody–drug conjugates
E Khera, GM Thurber
BioDrugs 32 (5), 465-480, 2018
Финансирование: US National Science Foundation
60 статей доступны в некоторых источниках
Antibody tumor penetration: transport opposed by systemic and antigen-mediated clearance
GM Thurber, MM Schmidt, KD Wittrup
Advanced drug delivery reviews 60 (12), 1421-1434, 2008
Финансирование: US National Institutes of Health
18F Labeled Nanoparticles for in Vivo PET-CT Imaging
NK Devaraj, EJ Keliher, GM Thurber, M Nahrendorf, R Weissleder
Bioconjugate chemistry 20 (2), 397-401, 2009
Финансирование: US National Institutes of Health
Reactive polymer enables efficient in vivo bioorthogonal chemistry
NK Devaraj, GM Thurber, EJ Keliher, B Marinelli, R Weissleder
Proceedings of the National Academy of Sciences 109 (13), 4762-4767, 2012
Финансирование: US National Institutes of Health
Single-cell and subcellular pharmacokinetic imaging allows insight into drug action in vivo
GM Thurber, KS Yang, T Reiner, RH Kohler, P Sorger, T Mitchison, ...
Nature communications 4 (1), 1504, 2013
Финансирование: US National Institutes of Health
Practical theoretic guidance for the design of tumor-targeting agents
KD Wittrup, GM Thurber, MM Schmidt, JJ Rhoden
Methods in enzymology 503, 255-268, 2012
Финансирование: US National Institutes of Health
Hybrid in vivo FMT-CT imaging of protease activity in atherosclerosis with customized nanosensors
M Nahrendorf, P Waterman, G Thurber, K Groves, M Rajopadhye, ...
Arteriosclerosis, thrombosis, and vascular biology 29 (10), 1444-1451, 2009
Финансирование: US National Institutes of Health
A systems approach for tumor pharmacokinetics
GM Thurber, R Weissleder
PloS one 6 (9), e24696, 2011
Финансирование: US National Institutes of Health
Accurate measurement of pancreatic islet β-cell mass using a second-generation fluorescent exendin-4 analog
T Reiner, G Thurber, J Gaglia, C Vinegoni, CW Liew, R Upadhyay, ...
Proceedings of the National Academy of Sciences 108 (31), 12815-12820, 2011
Финансирование: US National Institutes of Health, Howard Hughes Medical Institute
A mechanistic compartmental model for total antibody uptake in tumors
GM Thurber, KD Wittrup
Journal of theoretical biology 314, 57-68, 2012
Финансирование: US National Institutes of Health
Kinetics of anti-carcinoembryonic antigen antibody internalization: effects of affinity, bivalency, and stability
MM Schmidt, GM Thurber, KD Wittrup
Cancer immunology, immunotherapy 57, 1879-1890, 2008
Финансирование: US National Institutes of Health
Population dynamics of islet-infiltrating cells in autoimmune diabetes
AM Magnuson, GM Thurber, RH Kohler, R Weissleder, D Mathis, ...
Proceedings of the National Academy of Sciences 112 (5), 1511-1516, 2015
Финансирование: US National Institutes of Health, Juvenile Diabetes Research Foundation
Quantitative spatiotemporal analysis of antibody fragment diffusion and endocytic consumption in tumor spheroids
GM Thurber, KD Wittrup
Cancer research 68 (9), 3334-3341, 2008
Финансирование: US National Institutes of Health
Multiscale modeling of antibody-drug conjugates: connecting tissue and cellular distribution to whole animal pharmacokinetics and potential implications for efficacy
C Cilliers, H Guo, J Liao, N Christodolu, GM Thurber
The AAPS journal 18, 1117-1130, 2016
Финансирование: US National Institutes of Health
Tracking antibody distribution with near-infrared fluorescent dyes: impact of dye structure and degree of labeling on plasma clearance
C Cilliers, I Nessler, N Christodolu, GM Thurber
Molecular pharmaceutics 14 (5), 1623-1633, 2017
Финансирование: US National Institutes of Health
Improved tumor penetration and single-cell targeting of antibody–drug conjugates increases anticancer efficacy and host survival
C Cilliers, B Menezes, I Nessler, J Linderman, GM Thurber
Cancer research 78 (3), 758-768, 2018
Финансирование: US National Science Foundation, US National Institutes of Health
Increased Tumor Penetration of Single-Domain Antibody–Drug Conjugates Improves In Vivo Efficacy in Prostate Cancer Models
I Nessler, E Khera, S Vance, A Kopp, Q Qiu, TA Keating, AO Abu-Yousif, ...
Cancer research 80 (6), 1268-1278, 2020
Финансирование: US National Science Foundation, US National Institutes of Health
Co-administered antibody improves penetration of antibody–dye conjugate into human cancers with implications for antibody–drug conjugates
G Lu, N Nishio, NS van den Berg, BA Martin, S Fakurnejad, S van Keulen, ...
Nature Communications 11 (1), 5667, 2020
Финансирование: US National Institutes of Health, Netherlands Organisation for Scientific …
Quantitating Antibody Uptake In Vivo: Conditional Dependence on Antigen Expression Levels
GM Thurber, R Weissleder
Molecular imaging and biology 13, 623-632, 2011
Финансирование: US National Institutes of Health
Computational transport analysis of antibody-drug conjugate bystander effects and payload tumoral distribution: implications for therapy
E Khera, C Cilliers, S Bhatnagar, GM Thurber
Molecular Systems Design & Engineering 3 (1), 73-88, 2018
Финансирование: US National Science Foundation
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