Isolation and mechanical measurements of myofibrils from human induced pluripotent stem cell-derived cardiomyocytes JM Pioner, AW Racca, JM Klaiman, KC Yang, X Guan, L Pabon, ... Stem cell reports 6 (6), 885-896, 2016 | 107 | 2016 |
Ranolazine prevents phenotype development in a mouse model of hypertrophic cardiomyopathy R Coppini, L Mazzoni, C Ferrantini, F Gentile, JM Pioner, A Laurino, ... Circulation: Heart Failure 10 (3), e003565, 2017 | 95 | 2017 |
Pathogenesis of hypertrophic cardiomyopathy is mutation rather than disease specific: a comparison of the cardiac troponin T E163R and R92Q mouse models C Ferrantini, R Coppini, JM Pioner, F Gentile, B Tosi, L Mazzoni, B Scellini, ... Journal of the American Heart Association 6 (7), e005407, 2017 | 75 | 2017 |
Liquid crystalline networks toward regenerative medicine and tissue repair D Martella, P Paoli, JM Pioner, L Sacconi, R Coppini, L Santini, M Lulli, ... Small 13 (46), 1702677, 2017 | 71 | 2017 |
Development of light-responsive liquid crystalline elastomers to assist cardiac contraction C Ferrantini, JM Pioner, D Martella, R Coppini, N Piroddi, P Paoli, ... Circulation research 124 (8), e44-e54, 2019 | 70 | 2019 |
Electrophysiological and contractile effects of disopyramide in patients with obstructive hypertrophic cardiomyopathy: a translational study R Coppini, C Ferrantini, JM Pioner, L Santini, ZJ Wang, C Palandri, ... JACC: Basic to Translational Science 4 (7), 795-813, 2019 | 68 | 2019 |
Contractile properties of developing human fetal cardiac muscle AW Racca, JM Klaiman, JM Pioner, Y Cheng, AE Beck, ... The Journal of physiology 594 (2), 437-452, 2016 | 64 | 2016 |
Late sodium current inhibitors to treat exercise‐induced obstruction in hypertrophic cardiomyopathy: an in vitro study in human myocardium C Ferrantini, JM Pioner, L Mazzoni, F Gentile, B Tosi, A Rossi, ... British journal of pharmacology 175 (13), 2635-2652, 2018 | 61 | 2018 |
Absence of full-length dystrophin impairs normal maturation and contraction of cardiomyocytes derived from human-induced pluripotent stem cells JM Pioner, X Guan, JM Klaiman, AW Racca, L Pabon, V Muskheli, ... Cardiovascular research 116 (2), 368-382, 2020 | 58 | 2020 |
Novel insights on the relationship between T-tubular defects and contractile dysfunction in a mouse model of hypertrophic cardiomyopathy C Crocini, C Ferrantini, M Scardigli, R Coppini, L Mazzoni, E Lazzeri, ... Journal of Molecular and Cellular Cardiology 91, 42-51, 2016 | 53 | 2016 |
Optical investigation of action potential and calcium handling maturation of hiPSC-cardiomyocytes on biomimetic substrates JM Pioner, L Santini, C Palandri, D Martella, F Lupi, M Langione, ... International journal of molecular sciences 20 (15), 3799, 2019 | 48 | 2019 |
Mavacamten has a differential impact on force generation in myofibrils from rabbit psoas and human cardiac muscle B Scellini, N Piroddi, M Dente, G Vitale, JM Pioner, R Coppini, ... Journal of General Physiology 153 (7), e202012789, 2021 | 40 | 2021 |
A novel method of isolating myofibrils from primary cardiomyocyte culture suitable for myofibril mechanical study KC Woulfe, C Ferrara, JM Pioner, JH Mahaffey, R Coppini, B Scellini, ... Frontiers in Cardiovascular Medicine 6, 12, 2019 | 28 | 2019 |
R4496C RyR2 mutation impairs atrial and ventricular contractility C Ferrantini, R Coppini, B Scellini, C Ferrara, JM Pioner, L Mazzoni, ... Journal of General Physiology 147 (1), 39-52, 2016 | 28 | 2016 |
The relation between sarcomere energetics and the rate of isometric tension relaxation in healthy and diseased cardiac muscle G Vitale, C Ferrantini, N Piroddi, B Scellini, JM Pioner, B Colombini, ... Journal of muscle research and cell motility 42, 47-57, 2021 | 24 | 2021 |
Slower Calcium Handling Balances Faster Cross-Bridge Cycling in Human MYBPC3 HCM JM Pioner, G Vitale, S Steczina, M Langione, F Margara, L Santini, ... Circulation research 132 (5), 628-644, 2023 | 21 | 2023 |
Full-length dystrophin deficiency leads to contractile and calcium transient defects in human engineered heart tissues SB Bremner, CJ Mandrycky, A Leonard, AR Levinson, ES Rehn, ... Biophysical Journal 121 (3), 419a, 2022 | 21 | 2022 |
The harder the climb the better the view: The impact of substrate stiffness on cardiomyocyte fate S Querceto, R Santoro, A Gowran, B Grandinetti, G Pompilio, M Regnier, ... Journal of molecular and cellular cardiology 166, 36-49, 2022 | 20 | 2022 |
Advances in stem cell modeling of dystrophin-associated disease: implications for the wider world of dilated cardiomyopathy JM Pioner, A Fornaro, R Coppini, N Ceschia, L Sacconi, MA Donati, ... Frontiers in physiology 11, 368, 2020 | 20 | 2020 |
Calcium handling maturation and adaptation to increased substrate stiffness in human iPSC-derived cardiomyocytes: The impact of full-length dystrophin deficiency JM Pioner, L Santini, C Palandri, M Langione, B Grandinetti, S Querceto, ... Frontiers in Physiology 13, 1030920, 2022 | 12 | 2022 |