Integrative analysis of 111 reference human epigenomes A Kundaje, W Meuleman, J Ernst, M Bilenky, A Yen, A Heravi-Moussavi, ... Nature 518 (7539), 317-330, 2015 | 6402 | 2015 |
DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats D Brocks, CR Schmidt, M Daskalakis, HS Jang, NM Shah, D Li, J Li, ... Nature genetics 49 (7), 1052-1060, 2017 | 301 | 2017 |
Derivation of trophoblast stem cells from naïve human pluripotent stem cells C Dong, M Beltcheva, P Gontarz, B Zhang, P Popli, LA Fischer, SA Khan, ... elife 9, e52504, 2020 | 273 | 2020 |
DNA hypomethylation within specific transposable element families associates with tissue-specific enhancer landscape M Xie, C Hong, B Zhang, RF Lowdon, X Xing, D Li, X Zhou, HJ Lee, ... Nature genetics 45 (7), 836-841, 2013 | 255 | 2013 |
Transcriptional inhibiton of Hoxd4 expression by miRNA-10a in human breast cancer cells Y Tan, B Zhang, T Wu, G Skogerbø, X Zhu, X Guo, S He, R Chen BMC molecular biology 10, 1-9, 2009 | 239 | 2009 |
Striatal neurons directly converted from Huntington’s disease patient fibroblasts recapitulate age-associated disease phenotypes MB Victor, M Richner, HE Olsen, SW Lee, AM Monteys, C Ma, CJ Huh, ... Nature neuroscience 21 (3), 341-352, 2018 | 229 | 2018 |
Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm B Zhang, Y Zhou, N Lin, RF Lowdon, C Hong, RP Nagarajan, JB Cheng, ... Genome research 23 (9), 1522-1540, 2013 | 221 | 2013 |
Maintenance of age in human neurons generated by microRNA-based neuronal conversion of fibroblasts CJ Huh, B Zhang, MB Victor, S Dahiya, LFZ Batista, S Horvath, AS Yoo elife 5, e18648, 2016 | 214 | 2016 |
Evidence of CNIH3 involvement in opioid dependence EC Nelson, A Agrawal, AC Heath, R Bogdan, R Sherva, B Zhang, ... Molecular psychiatry 21 (5), 608-614, 2016 | 140 | 2016 |
Combining MeDIP-seq and MRE-seq to investigate genome-wide CpG methylation D Li, B Zhang, X Xing, T Wang Methods 72, 29-40, 2015 | 124 | 2015 |
Tissue-specific DNA methylation is conserved across human, mouse, and rat, and driven by primary sequence conservation J Zhou, RL Sears, X Xing, B Zhang, D Li, NB Rockweiler, HS Jang, ... BMC genomics 18, 1-17, 2017 | 115 | 2017 |
Robust principal component analysis for accurate outlier sample detection in RNA-Seq data X Chen, B Zhang, T Wang, A Bonni, G Zhao BMC bioinformatics 21, 1-20, 2020 | 95 | 2020 |
The NIEHS TaRGET II Consortium and environmental epigenomics T Wang, EC Pehrsson, D Purushotham, D Li, X Zhuo, B Zhang, ... Nature biotechnology 36 (3), 225-227, 2018 | 95 | 2018 |
Epigenomic annotation of genetic variants using the Roadmap Epigenome Browser X Zhou, D Li, B Zhang, RF Lowdon, NB Rockweiler, RL Sears, ... Nature biotechnology 33 (4), 345-346, 2015 | 95 | 2015 |
Developmental enhancers revealed by extensive DNA methylome maps of zebrafish early embryos HJ Lee, RF Lowdon, B Maricque, B Zhang, M Stevens, D Li, SL Johnson, ... Nature communications 6 (1), 6315, 2015 | 89 | 2015 |
A single transcription factor is sufficient to induce and maintain secretory cell architecture HYG Lo, RU Jin, G Sibbel, D Liu, A Karki, MS Joens, BB Madison, ... Genes & development 31 (2), 154-171, 2017 | 84 | 2017 |
Integrative analysis of 111 reference human epigenomes C Roadmap Epigenomics, A Kundaje, W Meuleman, J Ernst, M Bilenky, ... Nature 518 (7539), 317-30, 2015 | 76 | 2015 |
Transcriptome comparison of meniscus from patients with and without osteoarthritis RH Brophy, B Zhang, L Cai, RW Wright, LJ Sandell, MF Rai Osteoarthritis and cartilage 26 (3), 422-432, 2018 | 75 | 2018 |
A synthetic mechanogenetic gene circuit for autonomous drug delivery in engineered tissues RJ Nims, L Pferdehirt, NB Ho, A Savadipour, J Lorentz, S Sohi, J Kassab, ... Science Advances 7 (5), eabd9858, 2021 | 73 | 2021 |
Comparative DNA methylome analysis of endometrial carcinoma reveals complex and distinct deregulation of cancer promoters and enhancers B Zhang, XY Xing, J Li, RF Lowdon, Y Zhou, N Lin, B Zhang, V Sundaram, ... BMC genomics 15, 1-21, 2014 | 67 | 2014 |