| The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule BCS Cross, PJ Bond, PG Sadowski, BK Jha, J Zak, JM Goodman, ... Proceedings of the National Academy of Sciences, 2012 | 602 | 2012 |
| Chronic Obstructive Pulmonary Disease: Official diagnosis and treatment guidelines of the Czech Pneumological and Phthisiological Society; a novel phenotypic approach to COPD … V Koblizek, J Chlumsky, V Zindr, K Neumannova, J Zatloukal, J Zak, ... Biomedical Papers, 2013 | 194 | 2013 |
| ASPP2 controls epithelial plasticity and inhibits metastasis through β-catenin-dependent regulation of ZEB1 Y Wang, F Bu, C Royer, S Serres, JR Larkin, MS Soto, NR Sibson, ... Nature Cell Biology 16 (11), 1092-1104, 2014 | 165 | 2014 |
| A Code for RanGDP Binding in Ankyrin Repeats Defines a Nuclear Import Pathway M Lu, J Zak, S Chen, L Sanchez-Pulido, DT Severson, J Endicott, ... Cell 157 (5), 1130-1145, 2014 | 83 | 2014 |
| Heterozygous variants in KMT2E cause a spectrum of neurodevelopmental disorders and epilepsy AH O’Donnell-Luria, LS Pais, V Faundes, JC Wood, A Sveden, V Luria, ... The American Journal of Human Genetics 104 (6), 1210-1222, 2019 | 78 | 2019 |
| IL-27 promotes the expansion of self-renewing CD8+ T cells in persistent viral infection Z Huang*, J Zak*, I Pratumchai*, N Shaabani, VF Vartabedian, N Nguyen, ... Journal of Experimental Medicine 216 (8), 1791-1808, 2019 | 66 | 2019 |
| Progression of type 1 diabetes from the prediabetic stage is controlled by interferon-α signaling BS Marro, BC Ware, J Zak, JC de la Torre, H Rosen, MBA Oldstone Proceedings of the National Academy of Sciences, 2017 | 60 | 2017 |
| Discovery of Small Molecules for the Reversal of T Cell Exhaustion BS Marro*, J Zak*, RB Zavareh, JR Teijaro, LL Lairson, MBA Oldstone Cell Reports 29 (10), 3293-3302. e3, 2019 | 50 | 2019 |
| ASPP2 Links the Apical Lateral Polarity Complex to the Regulation of YAP Activity in Epithelial Cells C Royer, S Koch, X Qin, J Zak, L Buti, E Dudziec, S Zhong, I Ratnayaka, ... PloS one 9 (10), e111384, 2014 | 48 | 2014 |
| Establishing a Flow Process to Coumarin‐8‐Carbaldehydes as Important Synthetic Scaffolds J Zak, D Ron, E Riva, HP Harding, B Cross, IR Baxendale Chemistry-A European Journal 18 (32), 9901-9910, 2012 | 46 | 2012 |
| JAK inhibition enhances checkpoint blockade immunotherapy in patients with Hodgkin lymphoma J Zak, I Pratumchai, BS Marro, KL Marquardt, RB Zavareh, LL Lairson, ... Science 384 (6702), eade8520, 2024 | 39 | 2024 |
| Structural and non-coding variants increase the diagnostic yield of clinical whole genome sequencing for rare diseases AT Pagnamenta, C Camps, E Giacopuzzi, JM Taylor, M Hashim, ... Genome Medicine 15 (1), 94, 2023 | 24 | 2023 |
| B cell–derived IL-27 promotes control of persistent LCMV infection I Pratumchai, J Zak, Z Huang, B Min, MBA Oldstone, JR Teijaro Proceedings of the National Academy of Sciences 119 (3), e2116741119, 2022 | 21 | 2022 |
| Ruxolitinib Plus Nivolumab in Patients with R/R Hodgkin Lymphoma after Failure of Check-Point Inhibitors: Preliminary Report on Safety and Efficacy V Bachanova, L Hegerova, Q Cao, M Janakiram, J Maakaron, ... Blood 138 (Supplement 1), 230-230, 2021 | 13 | 2021 |
| IFNAR1 signaling in NK cells promotes persistent virus infection Z Huang*, SG Kang*, Y Li*, J Zak, N Shaabani, K Deng, J Shepherd, ... Science Advances 7 (13), eabb8087, 2021 | 12 | 2021 |
| ASPP2 deficiency causes features of 1q41q42 microdeletion syndrome J Zak, V Vives, D Szumska, A Vernet, JE Schneider, P Miller, EA Slee, ... Cell Death & Differentiation 23 (12), 1973-1984, 2016 | 8 | 2016 |
| Targeted desialylation and cytolysis of tumour cells by fusing a sialidase to a bispecific T-cell engager Z Yang, Y Hou, G Grande, JH Cho, C Wang, Y Shi, J Zak, Y Wan, K Qin, ... Nature Biomedical Engineering, 1-14, 2024 | 7 | 2024 |
| Aspp1: A Guardian of Hematopoietic Stem Cell Integrity J Zak, X Lu Cell Stem Cell 17 (1), 3-5, 2015 | 7 | 2015 |
| Transient EZH2 suppression by Tazemetostat during in vitro expansion maintains T-cell stemness and improves adoptive T-cell therapy Y Hou*, J Zak*, Y Shi, I Pratumchai, B Dinner, W Wang, K Qin, EW Weber, ... Cancer Immunology Research, 2024 | 5 | 2024 |
| Myeloid reprogramming by JAK inhibition enhances checkpoint blockade therapy J Zak, I Pratumchai, BS Marro, KL Marquardt, R Beheshti Zavareh, ... bioRxiv, 2022 | 5 | 2022 |
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