Lysosomal ion channels as decoders of cellular signals P Li, M Gu, H Xu Trends in biochemical sciences 44 (2), 110-124, 2019 | 154 | 2019 |
Parkinson’s disease-risk protein TMEM175 is a proton-activated proton channel in lysosomes M Hu, P Li, C Wang, X Feng, Q Geng, W Chen, M Marthi, W Zhang, C Gao, ... Cell 185 (13), 2292-2308. e20, 2022 | 139 | 2022 |
A voltage-dependent K+ channel in the lysosome is required for refilling lysosomal Ca2+ stores W Wang, X Zhang, Q Gao, M Lawas, L Yu, X Cheng, M Gu, N Sahoo, X Li, ... Journal of Cell Biology 216 (6), 1715-1730, 2017 | 100 | 2017 |
Natural product vindoline stimulates insulin secretion and efficiently ameliorates glucose homeostasis in diabetic murine models X Yao, F Chen, P Li, L Quan, J Chen, L Yu, H Ding, C Li, L Chen, Z Gao, ... Journal of ethnopharmacology 150 (1), 285-297, 2013 | 64 | 2013 |
The gating charge pathway of an epilepsy-associated potassium channel accommodates chemical ligands P Li, Z Chen, H Xu, H Sun, H Li, H Liu, H Yang, Z Gao, H Jiang, M Li Cell Research 23 (9), 1106-1118, 2013 | 61 | 2013 |
LRRC8 family proteins within lysosomes regulate cellular osmoregulation and enhance cell survival to multiple physiological stresses P Li, M Hu, C Wang, X Feng, ZZ Zhao, Y Yang, N Sahoo, M Gu, Y Yang, ... Proceedings of the National Academy of Sciences 117 (46), 29155-29165, 2020 | 58 | 2020 |
Agonist-specific voltage-dependent gating of lysosomal two-pore Na+ channels X Zhang, W Chen, P Li, R Calvo, N Southall, X Hu, M Bryant-Genevier, ... Elife 8, e51423, 2019 | 52 | 2019 |
Chukrasones A and B: Potential Kv1.2 Potassium Channel Blockers with New Skeletons from Chukrasia tabularis HB Liu, H Zhang, P Li, ZB Gao, JM Yue Organic Letters 14 (17), 4438-4441, 2012 | 40 | 2012 |
Bimodal voltage dependence of TRPA1: mutations of a key pore helix residue reveal strong intrinsic voltage-dependent inactivation X Wan, Y Lu, X Chen, J Xiong, Y Zhou, P Li, B Xia, M Li, MX Zhu, Z Gao Pflügers Archiv-European Journal of Physiology 466, 1273-1287, 2014 | 27 | 2014 |
Kv1. 2 potassium channel inhibitors from Chukrasia tabularis HB Liu, H Zhang, P Li, Y Wu, ZB Gao, JM Yue Organic & Biomolecular Chemistry 10 (7), 1448-1458, 2012 | 23 | 2012 |
The ethylene bis-dithiocarbamate fungicide Mancozeb activates voltage-gated KCNQ2 potassium channel P Li, J Zhu, Q Kong, B Jiang, X Wan, J Yue, M Li, H Jiang, J Li, Z Gao Toxicology letters 219 (3), 211-217, 2013 | 19 | 2013 |
The Human Ether-A-Go-Go–Related Gene Activator NS1643 Enhances Epilepsy-Associated KCNQ Channels P Li, X Chen, Q Zhang, Y Zheng, H Jiang, H Yang, Z Gao The Journal of pharmacology and experimental therapeutics 351 (3), 596-604, 2014 | 9 | 2014 |
Functional characterization and in vitro pharmacological rescue of KCNQ2 pore mutations associated with epileptic encephalopathy G Yang, F Tian, Y Shen, C Yang, H Yuan, P Li, Z Gao Acta Pharmacologica Sinica 44 (8), 1589-1599, 2023 | 6 | 2023 |
Comparison of the effects of DC031050, a class III antiarrhythmic agent, on hERG channel and three neuronal potassium channels P Li, H Sun, P Zhou, C Ma, G Hu, H Jiang, M Li, H Liu, Z Gao Acta Pharmacologica Sinica 33 (6), 728-736, 2012 | 6 | 2012 |
Characterization of the role of TMEM175 in an in vitro lysosomal H+ fluxes model C Yang, F Tian, M Hu, C Kang, M Ping, Y Liu, M Hu, H Xu, Y Yu, Z Gao, ... The FEBS Journal 290 (19), 4641-4659, 2023 | 5 | 2023 |
Lysosomal Ion Channels and Lysosome–Organelle Interactions W Cai, P Li, M Gu, H Xu Endolysosomal Voltage-Dependent Cation Channels, 93-108, 2023 | 5 | 2023 |
A Statistical thermodynamic model for ligands interacting with ion channels: theoretical model and experimental validation of the KCNQ2 channel F Bai, X Pi, P Li, P Zhou, H Yang, X Wang, M Li, Z Gao, H Jiang Frontiers in pharmacology 9, 150, 2018 | 3 | 2018 |
A theoretical model for calculating voltage sensitivity of ion channels and the application on Kv1. 2 potassium channel H Yang, Z Gao, P Li, K Yu, Y Yu, TL Xu, M Li, H Jiang Biophysical journal 102 (8), 1815-1825, 2012 | 3 | 2012 |
Nonreceptor tyrosine kinase ABL1 regulates lysosomal acidification by phosphorylating the ATP6V1B2 subunit of the vacuolar-type H+-ATPase C Song, Q Dong, Y Yao, Y Cui, C Zhang, L Lin, L Zhu, Y Hu, H Liu, Y Jin, ... Autophagy, 2025 | | 2025 |
An LQT2-related mutation in the voltage-sensing domain is involved in switching the gating polarity of hERG Z Liu, F Wang, H Yuan, F Tian, C Yang, F Hu, Y Liu, M Tang, M Ping, ... BMC biology 22 (1), 29, 2024 | | 2024 |