Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13559* | 2021 |
Multiple species of CPP32 and Mch2 are the major active caspases present in apoptotic cells L Faleiro, R Kobayashi, H Fearnhead, Y Lazebnik The EMBO journal, 1997 | 492 | 1997 |
Formation of large molecular weight fragments of DNA is a key committed step of apoptosis in thymocytes. GM Cohen, XM Sun, H Fearnhead, M MacFarlane, DG Brown, ... Journal of immunology (Baltimore, Md.: 1950) 153 (2), 507-516, 1994 | 314 | 1994 |
Increased membrane permeability of apoptotic thymocytes: a flow cytometric study MG Ormerod, XM Sun, RT Snowden, R Davies, H Fearnhead, GM Cohen Cytometry: The Journal of the International Society for Analytical Cytology …, 1993 | 242 | 1993 |
Oncogene-dependent apoptosis is mediated by caspase-9 HO Fearnhead, J Rodriguez, EE Govek, W Guo, R Kobayashi, G Hannon, ... Proceedings of the national academy of sciences 95 (23), 13664-13669, 1998 | 213 | 1998 |
An ICE‐like protease is a common mediator of apoptosis induced by diverse stimuli in human monocytic THP. 1 cells H Zhu, HO Fearnhead, GM Cohen FEBS letters 374 (2), 303-308, 1995 | 208 | 1995 |
A non-apoptotic role for caspase-9 in muscle differentiation TVA Murray, JM McMahon, BA Howley, A Stanley, T Ritter, A Mohr, ... Journal of cell science 121 (22), 3786-3793, 2008 | 198 | 2008 |
The Apaf‐1• procaspase‐9 apoptosome complex functions as a proteolytic‐based molecular timer S Malladi, M Challa‐Malladi, HO Fearnhead, SB Bratton The EMBO journal 28 (13), 1916-1925, 2009 | 180 | 2009 |
Molecular Cloning of ILP-2, a Novel Member of the Inhibitor of Apoptosis Protein Family BWM Richter, SS Mir, LJ Eiben, J Lewis, SB Reffey, A Frattini, L Tian, ... Molecular and cellular biology 21 (13), 4292-4301, 2001 | 158 | 2001 |
How do we fit ferroptosis in the family of regulated cell death? HO Fearnhead, P Vandenabeele, T Vanden Berghe Cell Death & Differentiation 24 (12), 1991-1998, 2017 | 151 | 2017 |
Intracellular nucleotides act as critical prosurvival factors by binding to cytochrome C and inhibiting apoptosome D Chandra, SB Bratton, MD Person, Y Tian, AG Martin, M Ayres, ... Cell 125 (7), 1333-1346, 2006 | 143 | 2006 |
An interleukin-1β-converting enzyme-like protease is a common mediator of apoptosis in thymocytes HO Fearnhead, D Dinsdale, GM Cohen FEBS letters 375 (3), 283-288, 1995 | 141 | 1995 |
New roles for old enzymes: killer caspases as the engine of cell behavior changes PF Connolly, R Jäger, HO Fearnhead Frontiers in physiology 5, 149, 2014 | 119 | 2014 |
Caspases as therapeutic targets B Howley, HO Fearnhead Journal of cellular and molecular medicine 12 (5a), 1502-1516, 2008 | 91 | 2008 |
Small molecule inhibitors of Apaf-1-related caspase-3/-9 activation that control mitochondrial-dependent apoptosis G Malet, AG Martin, M Orzaez, MJ Vicent, I Masip, G Sanclimens, ... Cell Death & Differentiation 13 (9), 1523-1532, 2006 | 87 | 2006 |
Oncogene-dependent apoptosis in extracts from drug-resistant cells. HO Fearnhead, ME McCurrach, J O'Neill, K Zhang, SW Lowe, ... Genes & development 11 (10), 1266-1276, 1997 | 84 | 1997 |
Autophagosomal IκBα degradation plays a role in the long term control of tumor necrosis factor-α-induced nuclear factor-κB (NF-κB) activity A Colleran, A Ryan, A O'Gorman, C Mureau, C Liptrot, P Dockery, ... Journal of Biological Chemistry 286 (26), 22886-22893, 2011 | 78 | 2011 |
Cdc2 activation is not required for thymocyte apoptosis C Norbury, M MacFarlane, H Fearnhead, GM Cohen Biochemical and biophysical research communications 202 (3), 1400-1406, 1994 | 75 | 1994 |
Apocytochrome c blocks caspase-9 activation and Bax-induced apoptosis AG Martin, HO Fearnhead Journal of Biological Chemistry 277 (52), 50834-50841, 2002 | 66 | 2002 |
Assay for ubiquitin ligase activity: high-throughput screen for inhibitors of HDM2 IV Davydov, D Woods, YJ Safiran, P Oberoi, HO Fearnhead, S Fang, ... Journal of biomolecular screening 9 (8), 695-703, 2004 | 64 | 2004 |