AKT/PKB signaling: navigating the network BD Manning, A Toker Cell 169 (3), 381-405, 2017 | 3555 | 2017 |
Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3, 4-bisphosphate TF Franke, DR Kaplan, LC Cantley, A Toker Science 275 (5300), 665-668, 1997 | 2001 | 1997 |
Signalling through the lipid products of phosphoinositide-3-OH kinase A Toker, LC Cantley Nature 387 (6634), 673-676, 1997 | 1723 | 1997 |
Sequence analysis of mutations and translocations across breast cancer subtypes S Banerji, K Cibulskis, C Rangel-Escareno, KK Brown, SL Carter, ... Nature 486 (7403), 405-409, 2012 | 1447 | 2012 |
Thrombin receptor ligation and activated Rac uncap actin filament barbed ends through phosphoinositide synthesis in permeabilized human platelets JH Hartwig, GM Bokoch, CL Carpenter, PA Janmey, LA Taylor, A Toker, ... Cell 82 (4), 643-653, 1995 | 853 | 1995 |
Regulation of protein kinase C ζ by PI 3-kinase and PDK-1 MM Chou, W Hou, J Johnson, LK Graham, MH Lee, CS Chen, AC Newton, ... Current Biology 8 (19), 1069-1078, 1998 | 809 | 1998 |
Activation of phosphoinositide 3-OH kinase by the α6β4 integrin promotes carcinoma invasion LM Shaw, I Rabinovitz, HHF Wang, A Toker, AM Mercurio Cell 91 (7), 949-960, 1997 | 766 | 1997 |
Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site A Toker, AC Newton Journal of Biological Chemistry 275 (12), 8271-8274, 2000 | 752 | 2000 |
Activation of protein kinase C family members by the novel polyphosphoinositides PtdIns-3, 4-P2 and PtdIns-3, 4, 5-P3. A Toker, M Meyer, KK Reddy, JR Falck, R Aneja, S Aneja, A Parra, ... Journal of Biological Chemistry 269 (51), 32358-32367, 1994 | 725 | 1994 |
Determination of the specific substrate sequence motifs of protein kinase C isozymes K Nishikawa, A Toker, FJ Johannes, Z Songyang, LC Cantley Journal of Biological Chemistry 272 (2), 952-960, 1997 | 698 | 1997 |
Cellular signaling: pivoting around PDK-1 A Toker, AC Newton Cell 103 (2), 185-188, 2000 | 560 | 2000 |
A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans S Paradis, M Ailion, A Toker, JH Thomas, G Ruvkun Genes & development 13 (11), 1438-1452, 1999 | 549 | 1999 |
Regulation of conventional protein kinase C isozymes by phosphoinositide-dependent kinase 1 (PDK-1) EM Dutil, A Toker, AC Newton Current Biology 8 (25), 1366-1375, 1998 | 544 | 1998 |
The role of NFAT transcription factors in integrin-mediated carcinoma invasion S Jauliac, C López-Rodriguez, LM Shaw, LF Brown, A Rao, A Toker Nature cell biology 4 (7), 540-544, 2002 | 526 | 2002 |
Akt blocks breast cancer cell motility and invasion through the transcription factor NFAT M Yoeli-Lerner, GK Yiu, I Rabinovitz, P Erhardt, S Jauliac, A Toker Molecular cell 20 (4), 539-550, 2005 | 517 | 2005 |
PI3K signaling in cancer: beyond AKT EC Lien, CC Dibble, A Toker Current opinion in cell biology 45, 62-71, 2017 | 475 | 2017 |
PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex P Liu, W Gan, YR Chin, K Ogura, J Guo, J Zhang, B Wang, J Blenis, ... Cancer discovery 5 (11), 1194-1209, 2015 | 452 | 2015 |
Signaling through protein kinase C A Toker Front Biosci 3 (1), 1134-47, 1998 | 445 | 1998 |
NFAT proteins: emerging roles in cancer progression M Mancini, A Toker Nature Reviews Cancer 9 (11), 810-820, 2009 | 444 | 2009 |
A rapid method for determining protein kinase phosphorylation specificity JE Hutti, ET Jarrell, JD Chang, DW Abbott, P Storz, A Toker, LC Cantley, ... Nature methods 1 (1), 27-29, 2004 | 411 | 2004 |