Conditional mutation of Pkd2 causes cystogenesis and upregulates β-catenin I Kim, T Ding, Y Fu, C Li, L Cui, A Li, P Lian, D Liang, DW Wang, C Guo, ... Journal of the American Society of Nephrology 20 (12), 2556-2569, 2009 | 111 | 2009 |
Elevated CXorf67 Expression in PFA Ependymomas Suppresses DNA Repair and Sensitizes to PARP inhibitors LL Jichang Han, Meng Yu, Yiqin Bai, Jianzhong Yu, Fei Jin, Chen Li, Rong ... Cancer Cell 38, 1-13, 2020 | 69* | 2020 |
Rapamycin treatment dose-dependently improves the cystic kidney in a new ADPKD mouse model via the mTORC1 and cell-cycle-associated CDK1/cyclin axis LCZ Li A, Fan S, Xu YC, Meng JL, Shen XF, Mao J, Zhang L, Zhang XS, Moeckel ... J Cell Mol Med 21 (8), 1619-1635, 2017 | 47 | 2017 |
Canonical Wnt inhibitors ameliorate cystogenesis in a mouse ortholog of human ADPKD A Li, Y Xu, S Fan, J Meng, X Shen, Q Xiao, Y Li, L Zhang, X Zhang, G Wu, ... JCI insight 3 (5), e95874, 2018 | 45 | 2018 |
Loss of Bicc1 impairs tubulomorphogenesis of cultured IMCD cells by disrupting E-cadherin-based cell-cell adhesion WG Fu Y, Kim I, Lian P, Li A, Zhou L, Li C, Liang D, Coffy RJ, Ma J, Zhao P ... Eur. J. Cell Biol 89 (6), 428-436, 2010 | 35 | 2010 |
Cystogenesis of ARPKD results from increased apoptosis in collecting duct epithelial cells of Pkhd1 mutant kidneys WG Hu B, He X, Li A, Qiu Q, Li C, Liang D, Zhao P, Coffey RJ, Zhan Q Exp. Cell Research 317 (2), 173-187, 2011 | 30 | 2011 |
NEDD4-family E3 ligase dysfunction due to PKHD1/Pkhd1 defects suggests a mechanistic model for ARPKD pathobiology GGG Kaimori JY, Lin CC, Outeda P, Garcia-Gonzalez MA, Menezes LF, Hartung EA ... Scientific Reports 7 (1), 7733-7749, 2017 | 26 | 2017 |
Human polycystin-2 transgene dose-dependently rescues ADPKD phenotypes in Pkd2 mutant mice A Li, X Tian, X Zhang, S Huang, Y Ma, D Wu, G Moeckel, S Somlo, G Wu The American Journal of Pathology 185 (10), 2843-2860, 2015 | 26 | 2015 |
Loss of polycystin-1 inhibits Bicc1 expression during mouse development WG Lian PW, Li A, Li Y, Liu HC, Liang D, Hu B, Lin D, Jiang D, Moeckel G, Qin DH PloS one 9 (3), e88816, 2014 | 24 | 2014 |
Pazopanib ameliorates acute lung injuries via inhibition of MAP3K2 and MAP3K3 Q Yuan, A Basit, W Liang, R Qu, Y Luan, C Ren, A Li, X Xu, X Liu, C Yang, ... Science translational medicine 13 (591), eabc2499, 2021 | 13 | 2021 |
DKK2 blockage-mediated immunotherapy enhances anti-angiogenic therapy of Kras mutated colorectal cancer J Hu, Z Wang, Z Chen, A Li, J Sun, M Zheng, J Wu, T Shen, J Qiao, L Li, ... Biomedicine & Pharmacotherapy 127, 110229, 2020 | 13 | 2020 |
Clinical Features of 167 Inpatients with Autosomal Dominant Polycystic Kidney Disease at a Single Center in China J Meng, Y Xu, A Li, S Fan, X Shen, D Ma, L Zhang, Z Hao, X Zhang, ... Medical science monitor: international medical journal of experimental and …, 2018 | 10 | 2018 |
The CUL5 E3 ligase complex negatively regulates central signaling pathways in CD8+ T cells X Liao, W Li, H Zhou, BK Rajendran, A Li, J Ren, Y Luan, DA Calderwood, ... Nature Communications 15 (1), 603, 2024 | 8 | 2024 |
Perspectives of Gene Therapies in Autosomal Dominant Polycystic Kidney Disease Y Xu, A Li, G Wu, C Liang Current gene therapy 17 (1), 43-49, 2017 | 7 | 2017 |
Preparation and characterization of a polyclonal antibody against human Fibrocystin-L GQW PW Lian , YL Fu , A Li , BZ Dai , ZW Ding Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 27 (1), 78-81, 2010 | 5* | 2010 |
LDL receptor-related protein 5 selectively transports unesterified polyunsaturated fatty acids to intracellular compartments W Tang, Y Luan, Q Yuan, A Li, S Chen, S Menacherry, L Young, D Wu Nature Communications 15 (1), 3068, 2024 | 2 | 2024 |
The Role of PKHD1 Mutation in Colorectal Cancer A Li Journal of Molecular Sciences 1 (1), 1-4, 2017 | 2 | 2017 |
Diagnosis and Treatment Status and Progress of Autosomal Dominant Polycystic Kidney Disease A Li International Journal of Nephrology & Therapeutics 3 (1), 40-45, 2017 | 2 | 2017 |
Construction of human PKD2 lentivirus to rectify polycystin-2 expression and Wnt/β-catenin signaling pathways in the Pkd2-null cell lines J Meng, Y XU, X Shen, A LI, S Fan, Z Hao, G WU, C Liang Chinese Journal of Urology, 62-68, 2018 | 1 | 2018 |
Research Progress on the Pathogenesis of Autosomal Recessive Polycystic Kidney Disease LCZ Shen XF, Xu YC, Meng JL, Li A, Fan S, Hao ZY, Wu GQ Chin J Pediatr. 56 (2), 157-160, 2018 | 1* | 2018 |