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Yong Ma
Yong Ma
Shanghai Hengrui Pharmaceutical Co., Ltd.
Нет подтвержденного адреса электронной почты
Название
Процитировано
Процитировано
Год
Cathepsin B is dispensable for cellular processing of cathepsin B-cleavable antibody–drug conjugates
NG Caculitan, J dela Cruz Chuh, Y Ma, D Zhang, KR Kozak, Y Liu, ...
Cancer research 77 (24), 7027-7037, 2017
1422017
Modulating antibody–drug conjugate payload metabolism by conjugation site and linker modification
D Su, KR Kozak, J Sadowsky, SF Yu, A Fourie-O’Donohue, C Nelson, ...
Bioconjugate chemistry 29 (4), 1155-1167, 2018
802018
Amino acid facilitates absorption of copper in the Caco-2 cell culture model
S Gao, T Yin, B Xu, Y Ma, M Hu
Life sciences 109 (1), 50-56, 2014
652014
Linker immolation determines cell killing activity of disulfide-linked pyrrolobenzodiazepine antibody–drug conjugates
D Zhang, TH Pillow, Y Ma, J Cruz-Chuh, KR Kozak, JD Sadowsky, ...
ACS Medicinal Chemistry Letters 7 (11), 988-993, 2016
592016
Disposition of flavonoids impacts their efficacy and safety
Y Ma, M Zeng, R Sun, M Hu
Current Drug Metabolism 15 (9), 841-864, 2014
512014
Disposition of flavonoids via recycling: Direct biliary excretion of enterically or extrahepatically derived flavonoid glucuronides
M Zeng, R Sun, S Basu, Y Ma, S Ge, T Yin, S Gao, J Zhang, M Hu
Molecular nutrition & food research 60 (5), 1006-1019, 2016
462016
Intratumoral payload concentration correlates with the activity of antibody–drug conjugates
D Zhang, SF Yu, SC Khojasteh, Y Ma, TH Pillow, JD Sadowsky, D Su, ...
Molecular cancer therapeutics 17 (3), 677-685, 2018
402018
Chemical structure and concentration of intratumor catabolites determine efficacy of antibody drug conjugates
D Zhang, SF Yu, Y Ma, K Xu, PS Dragovich, TH Pillow, L Liu, ...
Drug Metabolism and Disposition 44 (9), 1517-1523, 2016
392016
Immolation of p-Aminobenzyl Ether Linker and Payload Potency and Stability Determine the Cell-Killing Activity of Antibody–Drug Conjugates with Phenol …
D Zhang, H Le, J Cruz-Chuh, S Bobba, J Guo, L Staben, C Zhang, Y Ma, ...
Bioconjugate chemistry 29 (2), 267-274, 2018
372018
Glucuronides as potential anionic substrates of human cytochrome P450 2C8 (CYP2C8) miniperspective
Y Ma, Y Fu, SC Khojasteh, D Dalvie, D Zhang
Journal of Medicinal Chemistry 60 (21), 8691-8705, 2017
302017
Antibody drug conjugates differentiate uptake and DNA alkylation of pyrrolobenzodiazepines in tumors from organs of xenograft mice
Y Ma, SC Khojasteh, CECA Hop, HK Erickson, A Polson, TH Pillow, SF Yu, ...
Drug Metabolism and Disposition 44 (12), 1958-1962, 2016
302016
Exposure-efficacy analysis of antibody-drug conjugates delivering an excessive level of payload to tissues
D Zhang, PS Dragovich, SF Yu, Y Ma, TH Pillow, JD Sadowsky, D Su, ...
Drug Metabolism and Disposition 47 (10), 1146-1155, 2019
292019
Developing an activity and absorption-based quality control platform for Chinese traditional medicine: Application to Zeng-Sheng-Ping (Antitumor B)
T Yin, G Yang, Y Ma, B Xu, M Hu, M You, S Gao
Journal of ethnopharmacology 172, 195-201, 2015
272015
Quantitation of celecoxib and four of its metabolites in rat blood by UPLC-MS/MS clarifies their blood distribution patterns and provides more accurate pharmacokinetics profiles
Y Ma, S Gao, M Hu
Journal of Chromatography B 1001, 202-211, 2015
212015
Metabolism of phenolic compounds in LPS-stimulated Raw264. 7 cells can impact their anti-inflammatory efficacy: Indication of hesperetin
Y Ma, Y He, T Yin, H Chen, S Gao, M Hu
Journal of agricultural and food chemistry 66 (24), 6042-6052, 2018
192018
Mutual regioselective inhibition of human UGT1A1-mediated glucuronidation of four flavonoids
G Ma, B Wu, S Gao, Z Yang, Y Ma, M Hu
Molecular pharmaceutics 10 (8), 2891-2903, 2013
162013
Conjugation of Indoles to Antibodies through a Novel Self‐Immolating Linker
PS Dragovich, RA Blake, C Chen, J Chen, J Chuh, W den Besten, F Fan, ...
Chemistry–A European Journal 24 (19), 4830-4834, 2018
122018
Discovery of a Series of Potent, Selective, and Orally Bioavailable Nucleoside Inhibitors of CD73 That Demonstrates In Vivo Antitumor Activity
J Li, L Chen, RJ Billedeau, TF Stanton, JTP Chiang, CC Lee, W Li, ...
Journal of Medicinal Chemistry 66 (1), 345-370, 2022
102022
Intermediates Stabilized by Tris (triazolylmethyl) amines in the CuAAC Reaction
H Chen, C Cai, S Li, Y Ma, S Luozhong, Z Zhu
Chemistry–A European Journal 23 (19), 4730-4735, 2017
102017
dela Cruz-Chuh
DL Zhang, TH Pillow, Y Ma
J., Kozak, KR, Sadowsky, JD, Philips, GDL, Guo, J., Darwish, M., Fan, P …, 2016
82016
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