Cathepsin B is dispensable for cellular processing of cathepsin B-cleavable antibody–drug conjugates NG Caculitan, J dela Cruz Chuh, Y Ma, D Zhang, KR Kozak, Y Liu, ... Cancer research 77 (24), 7027-7037, 2017 | 142 | 2017 |
Modulating antibody–drug conjugate payload metabolism by conjugation site and linker modification D Su, KR Kozak, J Sadowsky, SF Yu, A Fourie-O’Donohue, C Nelson, ... Bioconjugate chemistry 29 (4), 1155-1167, 2018 | 80 | 2018 |
Amino acid facilitates absorption of copper in the Caco-2 cell culture model S Gao, T Yin, B Xu, Y Ma, M Hu Life sciences 109 (1), 50-56, 2014 | 65 | 2014 |
Linker immolation determines cell killing activity of disulfide-linked pyrrolobenzodiazepine antibody–drug conjugates D Zhang, TH Pillow, Y Ma, J Cruz-Chuh, KR Kozak, JD Sadowsky, ... ACS Medicinal Chemistry Letters 7 (11), 988-993, 2016 | 59 | 2016 |
Disposition of flavonoids impacts their efficacy and safety Y Ma, M Zeng, R Sun, M Hu Current Drug Metabolism 15 (9), 841-864, 2014 | 51 | 2014 |
Disposition of flavonoids via recycling: Direct biliary excretion of enterically or extrahepatically derived flavonoid glucuronides M Zeng, R Sun, S Basu, Y Ma, S Ge, T Yin, S Gao, J Zhang, M Hu Molecular nutrition & food research 60 (5), 1006-1019, 2016 | 46 | 2016 |
Intratumoral payload concentration correlates with the activity of antibody–drug conjugates D Zhang, SF Yu, SC Khojasteh, Y Ma, TH Pillow, JD Sadowsky, D Su, ... Molecular cancer therapeutics 17 (3), 677-685, 2018 | 40 | 2018 |
Chemical structure and concentration of intratumor catabolites determine efficacy of antibody drug conjugates D Zhang, SF Yu, Y Ma, K Xu, PS Dragovich, TH Pillow, L Liu, ... Drug Metabolism and Disposition 44 (9), 1517-1523, 2016 | 39 | 2016 |
Immolation of p-Aminobenzyl Ether Linker and Payload Potency and Stability Determine the Cell-Killing Activity of Antibody–Drug Conjugates with Phenol … D Zhang, H Le, J Cruz-Chuh, S Bobba, J Guo, L Staben, C Zhang, Y Ma, ... Bioconjugate chemistry 29 (2), 267-274, 2018 | 37 | 2018 |
Glucuronides as potential anionic substrates of human cytochrome P450 2C8 (CYP2C8) miniperspective Y Ma, Y Fu, SC Khojasteh, D Dalvie, D Zhang Journal of Medicinal Chemistry 60 (21), 8691-8705, 2017 | 30 | 2017 |
Antibody drug conjugates differentiate uptake and DNA alkylation of pyrrolobenzodiazepines in tumors from organs of xenograft mice Y Ma, SC Khojasteh, CECA Hop, HK Erickson, A Polson, TH Pillow, SF Yu, ... Drug Metabolism and Disposition 44 (12), 1958-1962, 2016 | 30 | 2016 |
Exposure-efficacy analysis of antibody-drug conjugates delivering an excessive level of payload to tissues D Zhang, PS Dragovich, SF Yu, Y Ma, TH Pillow, JD Sadowsky, D Su, ... Drug Metabolism and Disposition 47 (10), 1146-1155, 2019 | 29 | 2019 |
Developing an activity and absorption-based quality control platform for Chinese traditional medicine: Application to Zeng-Sheng-Ping (Antitumor B) T Yin, G Yang, Y Ma, B Xu, M Hu, M You, S Gao Journal of ethnopharmacology 172, 195-201, 2015 | 27 | 2015 |
Quantitation of celecoxib and four of its metabolites in rat blood by UPLC-MS/MS clarifies their blood distribution patterns and provides more accurate pharmacokinetics profiles Y Ma, S Gao, M Hu Journal of Chromatography B 1001, 202-211, 2015 | 21 | 2015 |
Metabolism of phenolic compounds in LPS-stimulated Raw264. 7 cells can impact their anti-inflammatory efficacy: Indication of hesperetin Y Ma, Y He, T Yin, H Chen, S Gao, M Hu Journal of agricultural and food chemistry 66 (24), 6042-6052, 2018 | 19 | 2018 |
Mutual regioselective inhibition of human UGT1A1-mediated glucuronidation of four flavonoids G Ma, B Wu, S Gao, Z Yang, Y Ma, M Hu Molecular pharmaceutics 10 (8), 2891-2903, 2013 | 16 | 2013 |
Conjugation of Indoles to Antibodies through a Novel Self‐Immolating Linker PS Dragovich, RA Blake, C Chen, J Chen, J Chuh, W den Besten, F Fan, ... Chemistry–A European Journal 24 (19), 4830-4834, 2018 | 12 | 2018 |
Discovery of a Series of Potent, Selective, and Orally Bioavailable Nucleoside Inhibitors of CD73 That Demonstrates In Vivo Antitumor Activity J Li, L Chen, RJ Billedeau, TF Stanton, JTP Chiang, CC Lee, W Li, ... Journal of Medicinal Chemistry 66 (1), 345-370, 2022 | 10 | 2022 |
Intermediates Stabilized by Tris (triazolylmethyl) amines in the CuAAC Reaction H Chen, C Cai, S Li, Y Ma, S Luozhong, Z Zhu Chemistry–A European Journal 23 (19), 4730-4735, 2017 | 10 | 2017 |
dela Cruz-Chuh DL Zhang, TH Pillow, Y Ma J., Kozak, KR, Sadowsky, JD, Philips, GDL, Guo, J., Darwish, M., Fan, P …, 2016 | 8 | 2016 |