Ambient ionization mass spectrometry: current understanding of mechanistic theory; analytical performance and application areas DJ Weston Analyst 135 (4), 661-668, 2010 | 452 | 2010 |
Direct analysis of pharmaceutical drug formulations using ion mobility spectrometry/quadrupole-time-of-flight mass spectrometry combined with desorption electrospray ionization DJ Weston, R Bateman, ID Wilson, TR Wood, CS Creaser Analytical chemistry 77 (23), 7572-7580, 2005 | 277 | 2005 |
Discovery of orally efficacious melanin-concentrating hormone receptor-1 antagonists as antiobesity agents. Synthesis, SAR, and biological evaluation of bicyclo [3.1. 0] hexyl … MD McBriar, H Guzik, S Shapiro, J Paruchova, R Xu, A Palani, JW Clader, ... Journal of medicinal chemistry 49 (7), 2294-2310, 2006 | 97 | 2006 |
Analysis of tryptic peptides using desorption electrospray ionisation combined with ion mobility spectrometry/mass spectrometry G Kaur‐Atwal, DJ Weston, PS Green, S Crosland, PLR Bonner, ... Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2007 | 75 | 2007 |
An approach to enhancing coverage of the urinary metabonome using liquid chromatography–ion mobility–mass spectrometry EL Harry, DJ Weston, AWT Bristow, ID Wilson, CS Creaser Journal of chromatography B 871 (2), 357-361, 2008 | 69 | 2008 |
Utility of spatially-resolved atmospheric pressure surface sampling and ionization techniques as alternatives to mass spectrometric imaging (MSI) in drug metabolism EQ Blatherwick, GJ Van Berkel, K Pickup, MK Johansson, ME Beaudoin, ... Xenobiotica 41 (8), 720-734, 2011 | 54 | 2011 |
Diagnostic biomarkers differentiating metastatic melanoma patients from healthy controls identified by an integrated MALDI‐TOF mass spectrometry/bioinformatic approach B Matharoo‐Ball, L Ratcliffe, L Lancashire, S Ugurel, AK Miles, DJ Weston, ... PROTEOMICS–Clinical Applications 1 (6), 605-620, 2007 | 52 | 2007 |
Enhanced analyte detection using in-source fragmentation of field asymmetric waveform ion mobility spectrometry-selected ions in combination with time-of-flight mass spectrometry LJ Brown, RW Smith, DE Toutoungi, JC Reynolds, AWT Bristow, A Ray, ... Analytical chemistry 84 (9), 4095-4103, 2012 | 50 | 2012 |
Analysis of pharmaceutical formulations using atmospheric pressure ion mobility spectrometry combined with liquid chromatography and nano-electrospray ionisation N Budimir, DJ Weston, CS Creaser Analyst 132 (1), 34-40, 2007 | 45 | 2007 |
In-membrane preconcentration/membrane inlet mass spectrometry of volatile and semivolatile organic compounds CS Creaser, DJ Weston, B Smith Analytical chemistry 72 (13), 2730-2736, 2000 | 44 | 2000 |
Bicyclic [4.1. 0] heptanes as phenyl replacements for melanin concentrating hormone receptor antagonists R Xu, S Li, J Paruchova, MD McBriar, H Guzik, A Palani, JW Clader, ... Bioorganic & medicinal chemistry 14 (10), 3285-3299, 2006 | 36 | 2006 |
Direct detection of a sulfonate ester genotoxic impurity by atmospheric-pressure thermal desorption–extractive electrospray–mass spectrometry NA Devenport, LC Sealey, FH Alruways, DJ Weston, JC Reynolds, ... Analytical Chemistry 85 (13), 6224-6227, 2013 | 31 | 2013 |
Direct determination of urinary creatinine by reactive-thermal desorption-extractive electrospray-ion mobility-tandem mass spectrometry. NA Devenport, DJ Blenkhorn, DJ Weston, JC Reynolds, CS Creaser Analytical Chemistry 86 (1), 357-361, 2014 | 29 | 2014 |
Enhanced performance in the determination of ibuprofen 1-β-O-acyl glucuronide in urine by combining high field asymmetric waveform ion mobility spectrometry with liquid … RW Smith, DE Toutoungi, JC Reynolds, AWT Bristow, A Ray, A Sage, ... Journal of chromatography A 1278, 76-81, 2013 | 28 | 2013 |
Quantification of proteins by flow cytometry: Quantification of human hepatic transporter P-gp and OATP1B1 using flow cytometry and mass spectrometry K Hogg, J Thomas, D Ashford, J Cartwright, R Coldwell, DJ Weston, ... Methods 82, 38-46, 2015 | 27 | 2015 |
Determination of free desmosine and isodesmosine as urinary biomarkers of lung disorder using ultra performance liquid chromatography–ion mobility-mass spectrometry NA Devenport, JC Reynolds, V Parkash, J Cook, DJ Weston, CS Creaser Journal of chromatography B 879 (32), 3797-3801, 2011 | 27 | 2011 |
Reactive metabolite trapping screens and potential pitfalls: bioactivation of a homomorpholine and formation of an unstable thiazolidine adduct EM Lenz, S Martin, R Schmidt, PE Morin, R Smith, DJ Weston, ... Chemical Research in Toxicology 27 (6), 968-980, 2014 | 24 | 2014 |
Evaluation of laser diode thermal desorption (LDTD) coupled with tandem mass spectrometry (MS/MS) for support of in vitro drug discovery assays: Increasing scope, robustness … I Beattie, A Smith, DJ Weston, P White, S Szwandt, L Sealey Journal of pharmaceutical and biomedical analysis 59, 18-28, 2012 | 23 | 2012 |
Design and synthesis of orally efficacious benzimidazoles as melanin-concentrating hormone receptor 1 antagonists WL Wu, DA Burnett, MA Caplen, MS Domalski, C Bennett, WJ Greenlee, ... Bioorganic & medicinal chemistry letters 16 (14), 3674-3678, 2006 | 23 | 2006 |
Bicyclo [3.1. 0] hexyl urea melanin concentrating hormone (MCH) receptor-1 antagonists: Impacting hERG liability via aryl modifications MD McBriar, H Guzik, S Shapiro, R Xu, J Paruchova, JW Clader, K O’Neill, ... Bioorganic & medicinal chemistry letters 16 (16), 4262-4265, 2006 | 21 | 2006 |