Cannabinoids control spasticity and tremor in a multiple sclerosis model D Baker, G Pryce, JL Croxford, P Brown, RG Pertwee, JW Huffman, ... Nature 404 (6773), 84-87, 2000 | 814 | 2000 |
Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors ML Casanova, C Blázquez, J Martínez-Palacio, C Villanueva, ... The Journal of clinical investigation 111 (1), 43-50, 2003 | 600 | 2003 |
Inhibition of Glioma Growth in Vivo by Selective Activation of the CB2 Cannabinoid Receptor C Sánchez, ML de Ceballos, TG del Pulgar, D Rueda, C Corbacho, ... Cancer research 61 (15), 5784-5789, 2001 | 587 | 2001 |
Inhibition of tumor angiogenesis by cannabinoids C Blázquez, ML Casanova, A Planas, T Gómez del Pulgar, C Villanueva, ... The FASEB journal 17 (3), 1-16, 2003 | 396 | 2003 |
Design, synthesis and pharmacology of cannabimimetic indoles JW Huffman, D Dai, BR Martin, DR Compton Bioorganic & Medicinal Chemistry Letters 4 (4), 563-566, 1994 | 394 | 1994 |
JWH018, a common constituent of ‘Spice’ herbal blends, is a potent and efficacious cannabinoid CB1 receptor agonist BK Atwood, J Huffman, A Straiker, K Mackie British journal of pharmacology 160 (3), 585-593, 2010 | 363 | 2010 |
Structure–activity relationships for 1-alkyl-3-(1-naphthoyl) indoles at the cannabinoid CB1 and CB2 receptors: steric and electronic effects of naphthoyl substituents. New … JW Huffman, G Zengin, MJ Wu, J Lu, G Hynd, K Bushell, ALS Thompson, ... Bioorganic & medicinal chemistry 13 (1), 89-112, 2005 | 360 | 2005 |
3-(1′, 1′-Dimethylbutyl)-1-deoxy-Δ8-THC and related compounds: synthesis of selective ligands for the CB2 receptor JW Huffman, J Liddle, S Yu, MM Aung, ME Abood, JL Wiley, BR Martin Bioorganic & medicinal chemistry 7 (12), 2905-2914, 1999 | 360 | 1999 |
Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding MM Aung, G Griffin, JW Huffman, MJ Wu, C Keel, B Yang, VM Showalter, ... Drug and alcohol dependence 60 (2), 133-140, 2000 | 352 | 2000 |
Structure-activity relationships of indole-and pyrrole-derived cannabinoids JL Wiley, DR Compton, D Dai, JAH Lainton, M Phillips, JW Huffman, ... Journal of Pharmacology and Experimental Therapeutics 285 (3), 995-1004, 1998 | 332 | 1998 |
CB2-receptor stimulation attenuates TNF-α-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion M Rajesh, P Mukhopadhyay, S Bátkai, G Hasko, L Liaudet, JW Huffman, ... American Journal of Physiology-Heart and Circulatory Physiology 293 (4 …, 2007 | 322 | 2007 |
Cannabinoid-2 receptor mediates protection against hepatic ischemia/reperfusion injury S Bátkai, D Osei-Hyiaman, H Pan, O El-Assal, M Rajesh, ... The FASEB journal: official publication of the Federation of American …, 2007 | 315 | 2007 |
Recent developments in the medicinal chemistry of cannabimimetic indoles, pyrroles and indenes JW Huffman, LW Padgett Frontiers in Medicinal Chemistry: Volume 4, 661-687, 2009 | 312 | 2009 |
Evidence for the presence of CB2-like cannabinoid receptors on peripheral nerve terminals G Griffin, SR Fernando, RA Ross, NG McKay, MLJ Ashford, D Shire, ... European journal of pharmacology 339 (1), 53-61, 1997 | 233 | 1997 |
Moving around the molecule: relationship between chemical structure and in vivo activity of synthetic cannabinoids JL Wiley, JA Marusich, JW Huffman Life sciences 97 (1), 55-63, 2014 | 218 | 2014 |
Synthesis and pharmacology of a very potent cannabinoid lacking a phenolic hydroxyl with high affinity for the CB2 receptor JW Huffman, S Yu, V Showalter, ME Abood, JL Wiley, DR Compton, ... Journal of medicinal chemistry 39 (20), 3875-3877, 1996 | 214 | 1996 |
3-Indolyl-1-naphthylmethanes: new cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB1 cannabinoid receptor JW Huffman, R Mabon, MJ Wu, J Lu, R Hart, DP Hurst, PH Reggio, ... Bioorganic & medicinal chemistry 11 (4), 539-549, 2003 | 208 | 2003 |
1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles JW Huffman, PV Szklennik, A Almond, K Bushell, DE Selley, H He, ... Bioorganic & Medicinal Chemistry Letters 15 (18), 4110-4113, 2005 | 204 | 2005 |
CB2 cannabinoid receptor agonists attenuate TNF‐α‐induced human vascular smooth muscle cell proliferation and migration M Rajesh, P Mukhopadhyay, G Hasko, JW Huffman, K Mackie, P Pacher British journal of pharmacology 153 (2), 347-357, 2008 | 190 | 2008 |
Cannabimimetic indoles, pyrroles and indenes JW Huffman Current medicinal chemistry 6, 705-720, 1999 | 182 | 1999 |