| Therapeutic opportunities within the DNA damage response LH Pearl, AC Schierz, SE Ward, B Al-Lazikani, FMG Pearl Nature Reviews Cancer 15 (3), 166-180, 2015 | 568 | 2015 |
| Conserved regulation of cardiac calcium uptake by peptides encoded in small open reading frames EG Magny, JI Pueyo, FMG Pearl, MA Cespedes, JE Niven, SA Bishop, ... Science 341 (6150), 1116-1120, 2013 | 391 | 2013 |
| The CATH domain structure database: new protocols and classification levels give a more comprehensive resource for exploring evolution LH Greene, TE Lewis, S Addou, A Cuff, T Dallman, M Dibley, O Redfern, ... Nucleic acids research 35 (suppl_1), D291-D297, 2007 | 357 | 2007 |
| The CATH database: an extended protein family resource for structural and functional genomics FMG Pearl, CF Bennett, JE Bray, AP Harrison, N Martin, A Shepherd, ... Nucleic acids research 31 (1), 452-455, 2003 | 355 | 2003 |
| The CATH Domain Structure Database and related resources Gene3D and DHS provide comprehensive domain family information for genome analysis F Pearl, A Todd, I Sillitoe, M Dibley, O Redfern, T Lewis, C Bennett, ... Nucleic acids research 33 (suppl_1), D247-D251, 2005 | 351 | 2005 |
| Assigning genomic sequences to CATH FMG Pearl, D Lee, JE Bray, I Sillitoe, AE Todd, AP Harrison, JM Thornton, ... Nucleic Acids Research 28 (1), 277-282, 2000 | 263 | 2000 |
| The CATH Database provides insights into protein structure/function relationships CA Orengo, FMG Pearl, JE Bray, AE Todd, AC Martin, L Lo Conte, ... Nucleic acids research 27 (1), 275-279, 1999 | 238 | 1999 |
| Protein folds, functions and evolution JM Thornton, CA Orengo, AE Todd, FMG Pearl Journal of molecular biology 293 (2), 333-342, 1999 | 232 | 1999 |
| Quantifying the similarities within fold space A Harrison, F Pearl, R Mott, J Thornton, C Orengo Journal of molecular biology 323 (5), 909-926, 2002 | 182 | 2002 |
| Bioinformatics in translational drug discovery SK Wooller, G Benstead-Hume, X Chen, Y Ali, FMG Pearl Bioscience reports 37 (4), BSR20160180, 2017 | 139 | 2017 |
| Recognizing the fold of a protein structure A Harrison, F Pearl, I Sillitoe, T Slidel, R Mott, J Thornton, C Orengo Bioinformatics 19 (14), 1748-1759, 2003 | 127 | 2003 |
| Repression of transcription at DNA breaks requires cohesin throughout interphase and prevents genome instability C Meisenberg, SI Pinder, SR Hopkins, SK Wooller, G Benstead-Hume, ... Molecular cell 73 (2), 212-223. e7, 2019 | 126 | 2019 |
| CATHEDRAL: a fast and effective algorithm to predict folds and domain boundaries from multidomain protein structures OC Redfern, A Harrison, T Dallman, FMG Pearl, CA Orengo PLoS computational biology 3 (11), e232, 2007 | 126 | 2007 |
| The CATH protein family database: a resource for structural and functional annotation of genomes CA Orengo, JE Bray, DWA Buchan, A Harrison, D Lee, FMG Pearl, ... PROTEOMICS: International Edition 2 (1), 11-21, 2002 | 116 | 2002 |
| VIDA: a virus database system for the organization of animal virus genome open reading frames MM Albà, D Lee, FMG Pearl, AJ Shepherd, N Martin, CA Orengo, ... Nucleic Acids Research 29 (1), 133-136, 2001 | 116 | 2001 |
| Cell-derived extracellular vesicles can be used as a biomarker reservoir for glioblastoma tumor subtyping R Lane, T Simon, M Vintu, B Solkin, B Koch, N Stewart, G Benstead-Hume, ... Communications biology 2 (1), 315, 2019 | 106 | 2019 |
| The CATH domain structure database CA Orengo, FMG Pearl, JM Thornton Structural bioinformatics 44, 249-271, 2003 | 100 | 2003 |
| Gene3D: structural assignment for whole genes and genomes using the CATH domain structure database DWA Buchan, AJ Shepherd, D Lee, FMG Pearl, SCG Rison, JM Thornton, ... Genome research 12 (3), 503-514, 2002 | 85 | 2002 |
| A rapid classification protocol for the CATH Domain Database to support structural genomics FMG Pearl, N Martin, JE Bray, DWA Buchan, AP Harrison, D Lee, ... Nucleic Acids Research 29 (1), 223-227, 2001 | 75 | 2001 |
| The CATH Dictionary of Homologous Superfamilies (DHS): a consensus approach for identifying distant structural homologues JE Bray, AE Todd, FMG Pearl, JM Thornton, CA Orengo Protein Engineering 13 (3), 153-165, 2000 | 74 | 2000 |
Christine OrengoProfessor of Bioinformatics, University College LondonOverená e-mailová adresa na: biochem.ucl.ac.uk