Mechanisms of Sec61/SecY-mediated protein translocation across membranes E Park, TA Rapoport Annual review of biophysics 41 (1), 21-40, 2012 | 440 | 2012 |
Structural and mechanistic insights into protein translocation TA Rapoport, L Li, E Park Annual review of cell and developmental biology 33 (1), 369-390, 2017 | 338 | 2017 |
Crystal structure of a substrate-engaged SecY protein-translocation channel L Li, E Park, JJ Ling, J Ingram, H Ploegh, TA Rapoport Nature 531 (7594), 395-399, 2016 | 208 | 2016 |
Structure of the SecY channel during initiation of protein translocation E Park, JF Ménétret, JC Gumbart, SJ Ludtke, W Li, A Whynot, TA Rapoport, ... Nature 506 (7486), 102-106, 2014 | 183 | 2014 |
Cryo-EM structure of the mitochondrial protein-import channel TOM complex at near-atomic resolution K Tucker, E Park Nature structural & molecular biology 26 (12), 1158-1166, 2019 | 172 | 2019 |
Structure of a CLC chloride ion channel by cryo-electron microscopy E Park, EB Campbell, R MacKinnon Nature 541 (7638), 500-505, 2017 | 162 | 2017 |
Ribosome binding of a single copy of the SecY complex: implications for protein translocation JF Menetret, J Schaletzky, WM Clemons, AR Osborne, SS Skånland, ... Molecular cell 28 (6), 1083-1092, 2007 | 149 | 2007 |
Preserving the membrane barrier for small molecules during bacterial protein translocation E Park, TA Rapoport Nature 473 (7346), 239-242, 2011 | 141 | 2011 |
The endoplasmic reticulum P5A-ATPase is a transmembrane helix dislocase MJ McKenna, SI Sim, A Ordureau, L Wei, JW Harper, S Shao, E Park Science 369 (6511), eabc5809, 2020 | 128 | 2020 |
Single copies of Sec61 and TRAP associate with a nontranslating mammalian ribosome JF Ménétret, RS Hegde, M Aguiar, SP Gygi, E Park, TA Rapoport, ... Structure 16 (7), 1126-1137, 2008 | 127 | 2008 |
Role of the GYVG pore motif of HslU ATPase in protein unfolding and translocation for degradation by HslV peptidase E Park, YM Rho, O Koh, SW Ahn, IS Seong, JJ Song, O Bang, JH Seol, ... Journal of Biological Chemistry 280 (24), 22892-22898, 2005 | 113 | 2005 |
Structure of the CLC-1 chloride channel from Homo sapiens E Park, R MacKinnon Elife 7, e36629, 2018 | 103 | 2018 |
Structure of the posttranslational Sec protein-translocation channel complex from yeast S Itskanov, E Park Science 363 (6422), 84-87, 2019 | 98 | 2019 |
Structure of the substrate-engaged SecA-SecY protein translocation machine C Ma, X Wu, D Sun, E Park, MA Catipovic, TA Rapoport, N Gao, L Li Nature communications 10 (1), 2872, 2019 | 74 | 2019 |
Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency to mTORC1 HR Shin, YR Citron, L Wang, L Tribouillard, CS Goul, R Stipp, ... Science 377 (6612), 1290-1298, 2022 | 71 | 2022 |
Bacterial protein translocation requires only one copy of the SecY complex in vivo E Park, TA Rapoport Journal of Cell Biology 198 (5), 881-893, 2012 | 68 | 2012 |
Stepwise gating of the Sec61 protein-conducting channel by Sec63 and Sec62 S Itskanov, KM Kuo, JC Gumbart, E Park Nature structural & molecular biology 28 (2), 162-172, 2021 | 58 | 2021 |
Structural basis of mitochondrial protein import by the TIM23 complex SI Sim, Y Chen, DL Lynch, JC Gumbart, E Park Nature 621 (7979), 620-626, 2023 | 55 | 2023 |
A common mechanism of Sec61 translocon inhibition by small molecules S Itskanov, L Wang, T Junne, R Sherriff, L Xiao, N Blanchard, WQ Shi, ... Nature chemical biology, 1-9, 2023 | 45 | 2023 |
Structural basis of polyamine transport by human ATP13A2 (PARK9) S Im Sim, S von Bülow, G Hummer, E Park Molecular Cell 81 (22), 4635-4649.e8, 2021 | 35 | 2021 |