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Simon Steiger
Simon Steiger
Overená e-mailová adresa na: dkfz.de
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Citované v
Citované v
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The pre-existing T cell landscape determines the response to bispecific T cell engagers in multiple myeloma patients
MJ Friedrich, P Neri, N Kehl, J Michel, S Steiger, M Kilian, N Leblay, ...
Cancer Cell 41 (4), 711-725. e6, 2023
1392023
Subclone-specific microenvironmental impact and drug response in refractory multiple myeloma revealed by single‐cell transcriptomics
SM Tirier, JP Mallm, S Steiger, AM Poos, MHS Awwad, N Giesen, ...
Nature Communications 12 (1), 6960, 2021
1052021
Resolving therapy resistance mechanisms in multiple myeloma by multiomics subclone analysis
AM Poos, N Prokoph, MJ Przybilla, JP Mallm, S Steiger, I Seufert, L John, ...
Blood 142 (19), 1633-1646, 2023
312023
Pheno-seq–linking visual features and gene expression in 3D cell culture systems
SM Tirier, J Park, F Preußer, L Amrhein, Z Gu, S Steiger, JP Mallm, ...
Scientific reports 9 (1), 12367, 2019
242019
Resolving the spatial architecture of myeloma and its microenvironment at the single-cell level
L John, AM Poos, A Brobeil, C Schinke, S Huhn, N Prokoph, R Lutz, ...
Nature Communications 14 (1), 5011, 2023
212023
Local emergence and decline of a SARS-CoV-2 variant with mutations L452R and N501Y in the spike protein
JP Mallm, C Bundschuh, H Kim, N Weidner, S Steiger, I Lander, K Börner, ...
Medrxiv, 2021.04. 27.21254849, 2021
162021
Dissection of gastric homeostasis in vivo facilitates permanent capture of isthmus-like stem cells in vitro
AJ Huebner, RA Gorelov, R Deviatiiarov, S Demharter, T Kull, RM Walsh, ...
Nature Cell Biology 25 (3), 390-403, 2023
102023
IgE type multiple myeloma exhibits hypermutated phenotype and tumor reactive T cells
N Kehl, M Kilian, J Michel, TR Wagner, S Uhrig, A Brobeil, LS Sester, ...
Journal for Immunotherapy of Cancer 10 (10), e005815, 2022
62022
Subclone-specific microenvironmental impact and drug response in refractory multiple myeloma revealed by single-cell transcriptomics. Nat. Commun. 12, 6960
SM Tirier, JP Mallm, S Steiger, AM Poos, MHS Awwad, N Giesen, ...
52021
Bone marrow immune signatures in multiple myeloma are linked to tumor heterogeneity and treatment outcome
S Steiger, R Lutz, N Prokoph, S Palit, SM Tirier, P Reichert, A Baumann, ...
Blood 140 (Supplement 1), 2083-2085, 2022
42022
The spatial heterogeneity in newly diagnosed multiple myeloma patients-from sub-clonal architecture to the immune microenvironment
L John, A Poos, SM Tirier, JP Mallm, N Prokoph, A Brobeil, R Lutz, ...
Blood 138, 729, 2021
32021
pagoda2: A package for analyzing and interactively exploring large single-cell RNA-seq datasets
N Barkas, B Joyce, P Kharchenko, S Steiger, J Fan, K Slowikowski
GitHub https://github. com/hms-dbmi/pagoda2, 2018
32018
Evolution of SARS-CoV-2 in the Rhine-Neckar/Heidelberg Region 01/2021–07/2023
C Bundschuh, N Weidner, J Klein, T Rausch, N Azevedo, A Telzerow, ...
Infection, Genetics and Evolution 119, 105577, 2024
22024
Multiple myeloma long-term survivors exhibit sustained immune alterations decades after first-line therapy
R Lutz, F Grünschläger, M Simon, MHS Awwad, M Bauer, S Yousefian, ...
Nature Communications 15 (1), 10396, 2024
12024
OA-23 Resolving therapy resistance mechanisms in multiple myeloma by multi-omics subclone analysis
A Poos, N Prokoph, M Przybilla, JP Mallm, S Steiger, I Seufert, L John, ...
Clinical Lymphoma Myeloma and Leukemia 23, S14-S15, 2023
12023
OAB-002: The preexisting T cell landscape determines response to T cell-engagers therapy in multiple myeloma
M Friedrich, N Kehl, P Neri, J Michel, N Leblay, R Maity, M Kilian, H Lee, ...
Clinical Lymphoma Myeloma and Leukemia 22, S1-S2, 2022
12022
Bone marrow breakout lesions act as key sites for tumor-immune cell diversification in multiple myeloma
R Lutz, AM Poos, L Solé-Boldo, L John, J Wagner, N Prokoph, ...
Science Immunology 10 (104), eadp6667, 2025
2025
Tumor Reactive T Cells Drive Clinical Responses to Multiple Myeloma
TR Wagner, N Kehl, S Steiger, T Boschert, M Kilian, KA Foster, ...
Blood 144, 1890, 2024
2024
P-151 Dietary Oleic Acid Influences the Myeloma Immune Microenvironment and Improves Clinical Outcomes
L Sester, J de Castilhos, V Borisov, A Gambihler, M Kilian, M Friedrich, ...
Clinical Lymphoma Myeloma and Leukemia 24, S126-S127, 2024
2024
Identification of tumor-reactive T cell receptors through functional single cell interaction analyses for personalized T cell therapy
TR Wagner, N Kehl, S Steiger, M Kilian, B Schönfelder, T Boschert, ...
Cancer Research 84 (6_Supplement), 14-14, 2024
2024
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Články 1–20