| Pharmacogenomics of GPCR drug targets AS Hauser, S Chavali, I Masuho, LJ Jahn, KA Martemyanov, DE Gloriam, ... Cell 172 (1), 41-54. e19, 2018 | 671 | 2018 |
| Mutations in GNAL cause primary torsion dystonia T Fuchs, R Saunders-Pullman, I Masuho, MS Luciano, D Raymond, ... Nature genetics 45 (1), 88-92, 2013 | 343 | 2013 |
| Distinct profiles of functional discrimination among G proteins determine the actions of G protein–coupled receptors I Masuho, O Ostrovskaya, GM Kramer, CD Jones, K Xie, KA Martemyanov Science signaling 8 (405), ra123-ra123, 2015 | 258 | 2015 |
| A global map of G protein signaling regulation by RGS proteins I Masuho, S Balaji, BS Muntean, NK Skamangas, S Chavali, JJG Tesmer, ... Cell 183 (2), 503-521. e19, 2020 | 134 | 2020 |
| GPR158/179 regulate G protein signaling by controlling localization and activity of the RGS7 complexes C Orlandi, E Posokhova, I Masuho, TA Ray, N Hasan, RG Gregg, ... Journal of Cell Biology 197 (6), 711-719, 2012 | 121 | 2012 |
| Dopamine receptor DAMB signals via Gq to mediate forgetting in Drosophila S Himmelreich, I Masuho, JA Berry, C MacMullen, NK Skamangas, ... Cell reports 21 (8), 2074-2081, 2017 | 95 | 2017 |
| Monitoring G protein activation in cells with BRET I Masuho, KA Martemyanov, NA Lambert G Protein-Coupled Receptors in Drug Discovery: Methods and Protocols, 107-113, 2015 | 93 | 2015 |
| Targeting G protein-coupled receptor signaling at the G protein level with a selective nanobody inhibitor S Gulati, H Jin, I Masuho, T Orban, Y Cai, E Pardon, KA Martemyanov, ... Nature communications 9 (1), 1996, 2018 | 92 | 2018 |
| RGS7/Gβ5/R7BP complex regulates synaptic plasticity and memory by modulating hippocampal GABABR-GIRK signaling O Ostrovskaya, K Xie, I Masuho, A Fajardo-Serrano, R Lujan, K Wickman, ... Elife 3, e02053, 2014 | 92 | 2014 |
| Retina-specific GTPase accelerator RGS11/Gβ5S/R9AP is a constitutive heterotrimer selectively targeted to mGluR6 in ON-bipolar neurons Y Cao, I Masuho, H Okawa, K Xie, J Asami, PJ Kammermeier, ... Journal of Neuroscience 29 (29), 9301-9313, 2009 | 91 | 2009 |
| Mutations in GNAL: a novel cause of craniocervical dystonia KR Kumar, K Lohmann, I Masuho, R Miyamoto, A Ferbert, T Lohnau, ... JAMA neurology 71 (4), 490-494, 2014 | 90 | 2014 |
| LGR5 receptor promotes cell–cell adhesion in stem cells and colon cancer cells via the IQGAP1–Rac1 pathway KS Carmon, X Gong, J Yi, L Wu, A Thomas, CM Moore, I Masuho, ... Journal of Biological Chemistry 292 (36), 14989-15001, 2017 | 86 | 2017 |
| Gαo is a major determinant of cAMP signaling in the pathophysiology of movement disorders BS Muntean, I Masuho, M Dao, LP Sutton, S Zucca, H Iwamoto, DN Patil, ... Cell reports 34 (5), 2021 | 82 | 2021 |
| Regulator of G protein signaling 8 (RGS8) requires its NH2 terminus for subcellular localization and acute desensitization of G protein-gated K+ channels O Saitoh, I Masuho, I Terakawa, S Nomoto, T Asano, Y Kubo Journal of Biological Chemistry 276 (7), 5052-5058, 2001 | 82 | 2001 |
| Novel GNB1 mutations disrupt assembly and function of G protein heterotrimers and cause global developmental delay in humans K Lohmann, I Masuho, DN Patil, H Baumann, E Hebert, S Steinrücke, ... Human molecular genetics 26 (6), 1078-1086, 2017 | 73 | 2017 |
| Diversity of the Gβγ complexes defines spatial and temporal bias of GPCR signaling I Masuho, NK Skamangas, BS Muntean, KA Martemyanov Cell systems 12 (4), 324-337. e5, 2021 | 68 | 2021 |
| Macromolecular composition dictates receptor and G protein selectivity of regulator of G protein signaling (RGS) 7 and 9-2 protein complexes in living cells I Masuho, K Xie, KA Martemyanov Journal of Biological Chemistry 288 (35), 25129-25142, 2013 | 62 | 2013 |
| Essential Role of the m2R-RGS6-IKACh Pathway in Controlling Intrinsic Heart Rate Variability E Posokhova, D Ng, A Opel, I Masuho, A Tinker, LG Biesecker, ... PloS one 8 (10), e76973, 2013 | 58 | 2013 |
| Genetic behavioral screen identifies an orphan anti-opioid system D Wang, HM Stoveken, S Zucca, M Dao, C Orlandi, C Song, I Masuho, ... Science 365 (6459), 1267-1273, 2019 | 55 | 2019 |
| Orphan Receptor GPR158 Is an Allosteric Modulator of RGS7 Catalytic Activity with an Essential Role in Dictating Its Expression and Localization in the Brain*♦ C Orlandi, K Xie, I Masuho, A Fajardo-Serrano, R Lujan, KA Martemyanov Journal of Biological Chemistry 290 (22), 13622-13639, 2015 | 53 | 2015 |
Kirill MartemyanovProfessor, The Scripps Research InstituteOverená e-mailová adresa na: scripps.edu