| Estrogen prevents bone loss via estrogen receptor α and induction of Fas ligand in osteoclasts T Nakamura, Y Imai, T Matsumoto, S Sato, K Takeuchi, K Igarashi, ... Cell 130 (5), 811-823, 2007 | 1230 | 2007 |
| Targeting androgen receptor in estrogen receptor-negative breast cancer M Ni, Y Chen, E Lim, H Wimberly, ST Bailey, Y Imai, DL Rimm, XS Liu, ... Cancer cell 20 (1), 119-131, 2011 | 442 | 2011 |
| Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis M Asagiri, T Hirai, T Kunigami, S Kamano, HJ Gober, K Okamoto, ... Science 319 (5863), 624-627, 2008 | 376 | 2008 |
| GlcNAcylation of histone H2B facilitates its monoubiquitination R Fujiki, W Hashiba, H Sekine, A Yokoyama, T Chikanishi, S Ito, Y Imai, ... Nature 480 (7378), 557-560, 2011 | 353 | 2011 |
| PKA-dependent regulation of the histone lysine demethylase complex PHF2–ARID5B A Baba, F Ohtake, Y Okuno, K Yokota, M Okada, Y Imai, M Ni, CA Meyer, ... Nature cell biology 13 (6), 668-675, 2011 | 222 | 2011 |
| Vitamin D receptor in osteoblasts is a negative regulator of bone mass control Y Yamamoto, T Yoshizawa, T Fukuda, Y Shirode-Fukuda, T Yu, K Sekine, ... Endocrinology 154 (3), 1008-1020, 2013 | 210 | 2013 |
| Estrogens maintain bone mass by regulating expression of genes controlling function and life span in mature osteoclasts Y Imai, MY Youn, S Kondoh, T Nakamura, A Kouzmenko, T Matsumoto, ... Annals of the New York Academy of Sciences 1173, E31-E39, 2009 | 158 | 2009 |
| Repair of an intercalated long bone defect with a synthetic biodegradable bone-inducing implant M Yoneda, H Terai, Y Imai, T Okada, K Nozaki, H Inoue, S Miyamoto, ... Biomaterials 26 (25), 5145-5152, 2005 | 155 | 2005 |
| Nuclear receptors in bone physiology and diseases Y Imai, MY Youn, K Inoue, I Takada, A Kouzmenko, S Kato Physiological reviews 93 (2), 481-523, 2013 | 126 | 2013 |
| Estrogen receptor α in osteocytes regulates trabecular bone formation in female mice S Kondoh, K Inoue, K Igarashi, H Sugizaki, Y Shirode-Fukuda, E Inoue, ... Bone 60, 68-77, 2014 | 125 | 2014 |
| Minireview: osteoprotective action of estrogens is mediated by osteoclastic estrogen receptor-α Y Imai, S Kondoh, A Kouzmenko, S Kato Molecular Endocrinology 24 (5), 877-885, 2010 | 108 | 2010 |
| ERKs induce expression of the transcriptional repressor Blimp-1 and subsequent plasma cell differentiation T Yasuda, K Kometani, N Takahashi, Y Imai, Y Aiba, T Kurosaki Science signaling 4 (169), ra25-ra25, 2011 | 104 | 2011 |
| Conditional deletion of Bmpr1a in differentiated osteoclasts increases osteoblastic bone formation, increasing volume of remodeling bone in mice M Okamoto, J Murai, Y Imai, D Ikegami, N Kamiya, S Kato, Y Mishina, ... Journal of Bone and Mineral Research 26 (10), 2511-2522, 2011 | 91 | 2011 |
| sFRP4-dependent Wnt signal modulation is critical for bone remodeling during postnatal development and age-related bone loss R Haraguchi, R Kitazawa, K Mori, R Tachibana, H Kiyonari, Y Imai, T Abe, ... Scientific reports 6 (1), 25198, 2016 | 87 | 2016 |
| Local delivery of siRNA using a biodegradable polymer application to enhance BMP-induced bone formation T Manaka, A Suzuki, K Takayama, Y Imai, H Nakamura, K Takaoka Biomaterials 32 (36), 9642-9648, 2011 | 80 | 2011 |
| RNA interference for noggin enhances the biological activity of bone morphogenetic proteins in vivo and in vitro K Takayama, A Suzuki, T Manaka, S Taguchi, Y Hashimoto, Y Imai, ... Journal of bone and mineral metabolism 27, 402-411, 2009 | 80 | 2009 |
| Osteoinductive capacity and heat stability of recombinant human bone morphogenetic protein-2 produced by Escherichia coli and dimerized by biochemical … K Yano, M Hoshino, Y Ohta, T Manaka, Y Naka, Y Imai, W Sebald, ... Journal of bone and mineral metabolism 27, 355-363, 2009 | 80 | 2009 |
| Epigenetic regulation of adipogenesis by PHF2 histone demethylase Y Okuno, F Ohtake, K Igarashi, J Kanno, T Matsumoto, I Takada, S Kato, ... Diabetes 62 (5), 1426-1434, 2013 | 75 | 2013 |
| JMJD5, a Jumonji C (JmjC) domain-containing protein, negatively regulates osteoclastogenesis by facilitating NFATc1 protein degradation MY Youn, A Yokoyama, S Fujiyama-Nakamura, F Ohtake, K Minehata, ... Journal of Biological Chemistry 287 (16), 12994-13004, 2012 | 73 | 2012 |
| The tumor suppressor menin prevents effector CD8 T-cell dysfunction by targeting mTORC1-dependent metabolic activation J Suzuki, T Yamada, K Inoue, S Nabe, M Kuwahara, N Takemori, ... Nature communications 9 (1), 3296, 2018 | 71 | 2018 |