Pooled CRISPR interference screening enables genome-scale functional genomics study in bacteria with superior performance T Wang, C Guan, J Guo, B Liu, Y Wu, Z Xie, C Zhang, XH Xing Nature communications 9 (1), 2475, 2018 | 252 | 2018 |
Improved sgRNA design in bacteria via genome-wide activity profiling J Guo, T Wang, C Guan, B Liu, C Luo, Z Xie, C Zhang, XH Xing Nucleic acids research 46 (14), 7052-7069, 2018 | 92 | 2018 |
Biosensor-assisted transcriptional regulator engineering for Methylobacterium extorquens AM1 to improve mevalonate synthesis by increasing the acetyl-CoA supply WF Liang, LY Cui, JY Cui, KW Yu, S Yang, TM Wang, CG Guan, C Zhang, ... Metabolic Engineering 39, 159-168, 2017 | 72 | 2017 |
Breeding of Methanol‐Tolerant Methylobacterium extorquens AM1 by Atmospheric and Room Temperature Plasma Mutagenesis Combined With Adaptive … LY Cui, SS Wang, CG Guan, WF Liang, ZL Xue, C Zhang, XH Xing Biotechnology Journal 13 (6), 1700679, 2018 | 43 | 2018 |
Functional discovery and production technology for natural bioactive peptides Y Wang, S Li, C Guan, D He, X Liao, H Chen, C Zhang, XH Xing Sheng wu Gong Cheng xue bao= Chinese Journal of Biotechnology 37 (6), 2166-2180, 2021 | 12 | 2021 |
Effects of Enzymatically Depolymerized Low Molecular Weight Heparins on CCl4-Induced Liver Fibrosis Y Yan, C Guan, S Du, W Zhu, Y Ji, N Su, X Mei, D He, Y Lu, C Zhang, ... Frontiers in Pharmacology 8, 514, 2017 | 12 | 2017 |
Strategic preparations of DPP-IV inhibitory peptides from Val-Pro-Xaa and Ile-Pro-Xaa peptide mixtures C Guan, S Iwatani, X Xing, N Yamamoto International Journal of Peptide Research and Therapeutics 27, 735-743, 2021 | 11 | 2021 |
Exploration of DPP-IV inhibitory peptide design rules assisted by the deep learning pipeline that identifies the restriction enzyme cutting site C Guan, J Luo, S Li, ZL Tan, Y Wang, H Chen, N Yamamoto, C Zhang, ... ACS omega 8 (42), 39662-39672, 2023 | 6 | 2023 |
Transcriptomic analysis of Andrias davidianus meat and experimental validation for exploring its bioactive components as functional foods C Guan, Z Tan, S Li, Y Wang, N Yamamoto, C Zhang, S Wang, J Chen, ... Food Science and Human Wellness 13 (1), 166-172, 2024 | 4 | 2024 |
Predicting a DNA-binding protein using random forest with multiple mathematical features C Guan, X Niu, F Shi, K Yang, N Li Bio-medical materials and engineering 26 (s1), S1883-S1889, 2015 | 3 | 2015 |
Assembly and analytical validation of a metagenomic reference catalog of human gut microbiota based on co-barcoding sequencing Y Huang, P Jiang, Z Liang, R Chen, Z Yue, X Xie, C Guan, X Fang Frontiers in Microbiology 14, 1145315, 2023 | 2 | 2023 |
天然活性多肽的发掘策略和生产技术 王彦珺, 李姝承, 关长阁, 何东, 廖锡豪, 王怡, 陈海红, 张翀, 邢新会 生物工程学报 37 (6), 2166-2180, 2021 | 2 | 2021 |
Cross-species binding spectrum of ACE2 to SARS-CoV-2 RBD X Liao, C Guan, C Wang, X Chen, X Lin, L Lu, L Li, T Wang, N Su, B Wu, ... Science China. Life Sciences 66 (3), 639, 2022 | 1 | 2022 |
Leveraging large language models for peptide antibiotic design C Guan, FC Fernandes, OL Franco, C de la Fuente-Nunez Cell Reports Physical Science 6 (1), 2025 | | 2025 |
Improving functional protein generation via foundation model-derived latent space likelihood optimization C Guan, F Wan, MDT Torres, C de la Fuente-Nunez bioRxiv, 2025.01. 07.631724, 2025 | | 2025 |
Screening of Chinese giant salamander meat hydrolysates with DPP-IV inhibitory activity and systematic elucidation of their hypoglycemic functions in mouse model S Li, C Guan, Y Wang, H Chen, W Li, S Wang, C Zhang, XH Xing Food Science and Human Wellness, 2024 | | 2024 |
Venomics AI: a computational exploration of global venoms for antibiotic discovery C Guan, MDT Torres, S Li, C de la Fuente-Nunez bioRxiv, 2024.12. 17.628923, 2024 | | 2024 |