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P J Michael Deans
P J Michael Deans
Overená e-mailová adresa na: yale.edu
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Citované v
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Synergistic effects of common schizophrenia risk variants
N Schrode, SM Ho, K Yamamuro, A Dobbyn, L Huckins, MR Matos, ...
Nature genetics 51 (10), 1475-1485, 2019
2322019
Neuronal impact of patient-specific aberrant NRXN1α splicing
E Flaherty, S Zhu, N Barretto, E Cheng, PJM Deans, MB Fernando, ...
Nature genetics 51 (12), 1679-1690, 2019
1212019
Psychosis risk candidate ZNF804A localizes to synapses and regulates neurite formation and dendritic spine structure
PJM Deans, P Raval, KJ Sellers, NJF Gatford, S Halai, RRR Duarte, ...
Biological psychiatry 82 (1), 49-61, 2017
1022017
Common genetic variation in humans impacts in vitro susceptibility to SARS-CoV-2 infection
K Dobrindt, DA Hoagland, C Seah, B Kassim, CP O'Shea, A Murphy, ...
Stem cell reports 16 (3), 505-518, 2021
622021
Modeling gene× environment interactions in PTSD using human neurons reveals diagnosis-specific glucocorticoid-induced gene expression
C Seah, MS Breen, T Rusielewicz, HN Bader, C Xu, CJ Hunter, ...
Nature neuroscience 25 (11), 1434-1445, 2022
412022
Characterisation of neurons derived from a cortical human neural stem cell line CTX0E16
GW Anderson, PJM Deans, RDT Taylor, P Raval, D Chen, H Lowder, ...
Stem cell research & therapy 6, 1-20, 2015
242015
Applying stem cells and CRISPR engineering to uncover the etiology of schizophrenia
PJM Deans, KJ Brennand
Current opinion in neurobiology 69, 193-201, 2021
232021
Using the dCas9-KRAB system to repress gene expression in hiPSC-derived NGN2 neurons
A Li, S Cartwright, A Yu, SM Ho, N Schrode, PJM Deans, MR Matos, ...
STAR protocols 2 (2), 100580, 2021
112021
Analysis framework and experimental design for evaluating synergy-driving gene expression
N Schrode, C Seah, PJM Deans, G Hoffman, KJ Brennand
Nature protocols 16 (2), 812-840, 2021
112021
Convergent impact of schizophrenia risk genes
KG Townsley, A Li, PM Deans, JF Fullard, A Yu, S Cartwright, W Zhang, ...
92022
Attenuated transcriptional response to pro-inflammatory cytokines in schizophrenia hiPSC-derived neural progenitor cells
A Bhat, H Irizar, ACM Couch, P Raval, RRR Duarte, LD Polit, B Hanger, ...
Brain, Behavior, and Immunity 105, 82-97, 2022
82022
Neuroligin-3 and neuroligin-4X form nanoscopic clusters and regulate growth cone organization and size
NJF Gatford, PJM Deans, RRR Duarte, G Chennell, KJ Sellers, P Raval, ...
Human Molecular Genetics 31 (5), 674-691, 2022
82022
Precise Therapeutic Targeting of Distinct NRXN1+/− Mutations
MB Fernando, Y Fan, Y Zhang, S Kammourh, AN Murphy, S Ghorbani, ...
bioRxiv, 2023.10. 28.564543, 2023
5*2023
Non-additive effects of schizophrenia risk genes reflect convergent downstream function
PJM Deans, C Seah, J Johnson, JG Gonzalez, K Townsley, E Cao, ...
medRxiv, 2023
52023
Dynamic stress-and inflammatory-based regulation of psychiatric risk loci in human neurons
KG Retallick-Townsley, S Lee, S Cartwright, S Cohen, A Sen, M Jia, ...
bioRxiv, 2024
32024
Nanoscopic Clustering of Neuroligin-3 and Neuroligin-4X Regulates Growth Cone Organization and Size
NJF Gatford, PJ Michael Deans, RRR Duarte, G Chennell, P Raval, ...
bioRxiv, 546499, 2019
22019
O10. 7. Investigating the mechanisms underlying the beneficial effects of estrogens in schizophrenia
PJ Michael Deans, C Shum, L Perfect, M Conforti, R Duarte, ...
Schizophrenia Bulletin 44 (suppl_1), S105-S105, 2018
22018
Better together: Non-additive interactions between schizophrenia risk genes
PJM Deans, KJ Brennand
Cell Genomics 3 (9), 2023
12023
Schizophrenia risk mapping and functional engineering of the 3D genome in three neuronal subtypes
SK Powell, W Liao, C O’Shea, S Kammourh, S Ghorbani, R Rigat, R Elahi, ...
bioRxiv, 2023
12023
Author Correction: Modeling gene× environment interactions in PTSD using human neurons reveals diagnosis-specific glucocorticoid-induced gene expression
C Seah, MS Breen, T Rusielewicz, HN Bader, C Xu, CJ Hunter, ...
Nature Neuroscience 28 (1), 214, 2024
2024
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Články 1–20