Excluded‐Volume Effects in Living Cells D Gnutt, M Gao, O Brylski, M Heyden, S Ebbinghaus Angewandte Chemie International Edition 54 (8), 2548-2551, 2015 | 202 | 2015 |
Effects of in vivo conditions on amyloid aggregation MC Owen, D Gnutt, M Gao, SKTS Wärmländer, J Jarvet, A Gräslund, ... Chemical Society Reviews 48 (14), 3946-3996, 2019 | 184 | 2019 |
The macromolecular crowding effect–from in vitro into the cell D Gnutt, S Ebbinghaus Biological chemistry 397 (1), 37-44, 2016 | 121 | 2016 |
Optimizing the Cell Painting assay for image-based profiling BA Cimini, SN Chandrasekaran, M Kost-Alimova, L Miller, A Goodale, ... Nature protocols 18 (7), 1981-2013, 2023 | 89 | 2023 |
RNA Hairpin Folding in the Crowded Cell M Gao, D Gnutt, A Orban, B Appel, F Righetti, R Winter, F Narberhaus, ... Angewandte Chemie International Edition 55 (9), 3224-3228, 2016 | 89 | 2016 |
JUMP Cell Painting dataset: morphological impact of 136,000 chemical and genetic perturbations SN Chandrasekaran, J Ackerman, E Alix, DM Ando, J Arevalo, M Bennion, ... bioRxiv, 2023.03. 23.534023, 2023 | 70 | 2023 |
Stability effect of quinary interactions reversed by single point mutations D Gnutt, S Timr, J Ahlers, B König, E Manderfeld, M Heyden, F Sterpone, ... Journal of the American Chemical Society 141 (11), 4660-4669, 2019 | 66 | 2019 |
Inhibition of huntingtin exon-1 aggregation by the molecular tweezer CLR01 T Vöpel, K Bravo-Rodriguez, S Mittal, S Vachharajani, D Gnutt, ... Journal of the American Chemical Society 139 (16), 5640-5643, 2017 | 56 | 2017 |
Conformational dynamics and self-association of intrinsically disordered Huntingtin exon 1 in cells S Büning, A Sharma, S Vachharajani, E Newcombe, A Ormsby, M Gao, ... Physical Chemistry Chemical Physics 19 (17), 10738-10747, 2017 | 30 | 2017 |
Imperfect crowding adaptation of mammalian cells towards osmotic stress and its modulation by osmolytes D Gnutt, O Brylski, E Edengeiser, M Havenith, S Ebbinghaus Molecular BioSystems 13 (11), 2218-2221, 2017 | 28 | 2017 |
Role of Electrostatics in Protein–RNA Binding: The Global vs the Local Energy Landscape Z Ghaemi, I Guzman, D Gnutt, Z Luthey-Schulten, M Gruebele The Journal of Physical Chemistry B 121 (36), 8437-8446, 2017 | 26 | 2017 |
Self-supervision advances morphological profiling by unlocking powerful image representations V Kim, N Adaloglou, M Osterland, FM Morelli, M Halawa, T König, D Gnutt, ... Scientific Reports 15 (1), 4876, 2025 | 23 | 2025 |
The Unfolding Journey of Superoxide Dismutase 1 Barrels Under Crowding: Atomistic Simulations Shed Light on Intermediate States and Their Interactions With Crowders S Timr, D Gnutt, S Ebbinghaus, F Sterpone The journal of physical chemistry letters 11 (10), 4206-4212, 2020 | 21 | 2020 |
Cryo-EM structural studies of the agonist complexed human TRPV4 ion-channel reveals novel structural rearrangements resulting in an open-conformation M Botte, AKC Ulrich, R Adaixo, D Gnutt, A Brockmann, D Bucher, ... BioRxiv, 2020.10. 13.334797, 2020 | 16 | 2020 |
Protein folding modulation in cells subject to differentiation and stress D Gnutt, L Sistemich, S Ebbinghaus Frontiers in molecular biosciences 6, 38, 2019 | 16 | 2019 |
Superoxide Dismutase 1 Folding Stability as a Target for Molecular Tweezers in SOD1‐Related Amyotrophic Lateral Sclerosis N Samanta, YB Ruiz‐Blanco, Z Fetahaj, D Gnutt, C Lantz, JA Loo, ... ChemBioChem 23 (21), e202200396, 2022 | 9 | 2022 |
Cellular ATP levels determine the stability of a nucleotide kinase O Brylski, P Shrestha, P Gnutt, D Gnutt, JW Mueller, S Ebbinghaus Frontiers in Molecular Biosciences 8, 790304, 2021 | 8 | 2021 |
Cryo-EM structural studies of the agonist complexed human TRPV4 ion-channel reveals novel structural rearrangements resulting in an open-conformation. bioRxiv: 2020.2010. 2013 … M Botte, AKC Ulrich, R Adaixo, D Gnutt, A Brockmann, D Bucher, ... | 4 | 2020 |
Cell painting unravels insecticidal modes of action on Spodoptera frugiperda insect cells FA Hecker, B Leggio, T König, V Kim, M Osterland, D Gnutt, K Niehaus, ... Pesticide Biochemistry and Physiology, 105983, 2024 | 3 | 2024 |
Intracellular spatially-targeted chemical chaperones increase native state stability of mutant SOD1 barrel SS Ribeiro, D Gnutt, S Azoulay-Ginsburg, Z Fetahaj, E Spurlock, ... Biological Chemistry 404 (10), 909-930, 2023 | 2 | 2023 |