| Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale X Li, Z Li, H Zhou, SM Gaynor, Y Liu, H Chen, R Sun, R Dey, DK Arnett, ... Nature genetics 52 (9), 969-983, 2020 | 215 | 2020 |
| Association between smoking history and tumor mutation burden in advanced non–small cell lung cancer X Wang, B Ricciuti, T Nguyen, X Li, MS Rabin, MM Awad, X Lin, ... Cancer research 81 (9), 2566-2573, 2021 | 122 | 2021 |
| Genetic overlap of chronic obstructive pulmonary disease and cardiovascular disease-related traits: a large-scale genome-wide cross-trait analysis Z Zhu, X Wang, X Li, Y Lin, S Shen, CL Liu, BD Hobbs, K Hasegawa, ... Respiratory research 20, 1-14, 2019 | 101 | 2019 |
| FAVOR: functional annotation of variants online resource and annotator for variation across the human genome H Zhou, T Arapoglou, X Li, Z Li, X Zheng, J Moore, A Asok, S Kumar, ... Nucleic Acids Research 51 (D1), D1300-D1311, 2023 | 82 | 2023 |
| A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies Z Li, X Li, H Zhou, SM Gaynor, MS Selvaraj, T Arapoglou, C Quick, Y Liu, ... Nature methods 19 (12), 1599-1611, 2022 | 75 | 2022 |
| Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer J Byun, Y Han, Y Li, J Xia, E Long, J Choi, X Xiao, M Zhu, W Zhou, R Sun, ... Nature genetics 54 (8), 1167-1177, 2022 | 72 | 2022 |
| Shared genetic architecture between metabolic traits and Alzheimer’s disease: a large-scale genome-wide cross-trait analysis Z Zhu, Y Lin, X Li, JA Driver, L Liang Human genetics 138, 271-285, 2019 | 61 | 2019 |
| Dynamic scan procedure for detecting rare-variant association regions in whole-genome sequencing studies Z Li, X Li, Y Liu, J Shen, H Chen, H Zhou, AC Morrison, E Boerwinkle, ... The American Journal of Human Genetics 104 (5), 802-814, 2019 | 59 | 2019 |
| Whole genome sequence analysis of blood lipid levels in> 66,000 individuals MS Selvaraj, X Li, Z Li, A Pampana, DY Zhang, J Park, S Aslibekyan, ... Nature communications 13 (1), 5995, 2022 | 51 | 2022 |
| Principles and methods of in-silico prioritization of non-coding regulatory variants PH Lee, C Lee, X Li, B Wee, T Dwivedi, M Daly Human genetics 137, 15-30, 2018 | 47 | 2018 |
| Powerful, scalable and resource-efficient meta-analysis of rare variant associations in large whole genome sequencing studies X Li, C Quick, H Zhou, SM Gaynor, Y Liu, H Chen, MS Selvaraj, R Sun, ... Nature genetics 55 (1), 154-164, 2023 | 39 | 2023 |
| Spatiotemporal patterns of neuronal subtype genesis suggest hierarchical development of retinal diversity ER West, SW Lapan, CH Lee, KM Kajderowicz, X Li, CL Cepko Cell Reports 38 (1), 2022 | 30 | 2022 |
| A multi-dimensional integrative scoring framework for predicting functional variants in the human genome X Li, G Yung, H Zhou, R Sun, Z Li, K Hou, MJ Zhang, Y Liu, T Arapoglou, ... The American Journal of Human Genetics 109 (3), 446-456, 2022 | 24 | 2022 |
| Whole-genome sequencing analysis of human metabolome in multi-ethnic populations EV Feofanova, MR Brown, T Alkis, AM Manuel, X Li, UA Tahir, Z Li, ... nature communications 14 (1), 3111, 2023 | 23 | 2023 |
| Target population statistical inference with data integration across multiple sources—an approach to mitigate information shortage in rare disease clinical trials X Li, Y Song Statistics in Biopharmaceutical Research 12 (3), 322-333, 2020 | 22 | 2020 |
| Deciphering the impact of genomic variation on function Code of Conduct Committee (alphabetical by last name) Cody Sarah 33 Farrell ... Nature 633 (8028), 47-57, 2024 | 16 | 2024 |
| STAAR workflow: a cloud-based workflow for scalable and reproducible rare variant analysis SM Gaynor, KE Westerman, LL Ackovic, X Li, Z Li, AK Manning, ... Bioinformatics 38 (11), 3116-3117, 2022 | 12 | 2022 |
| A versatile toolkit for molecular QTL mapping and meta-analysis at scale C Quick, L Guan, Z Li, X Li, R Dey, Y Liu, L Scott, X Lin Biorxiv, 2020.12. 18.423490, 2020 | 10 | 2020 |
| Rare variants in long non-coding RNAs are associated with blood lipid levels in the TOPMed whole-genome sequencing study Y Wang, MS Selvaraj, X Li, Z Li, JA Holdcraft, DK Arnett, JC Bis, ... The American Journal of Human Genetics 110 (10), 1704-1717, 2023 | 9 | 2023 |
| The impact of genomic variation on function (IGVF) consortium IGVF Consortium ArXiv, arXiv: 2307.13708 v1, 2023 | 9 | 2023 |
Xihong LinHarvard UniversityOverená e-mailová adresa na: hsph.harvard.edu